AP Psychology 120 – 2011/2012 Unit #3 – Biological Bases of Behavior Section 1 - Communication in the Nervous System Your nervous system is a complex communication network in which signals are constantly being transmitted, received and integrated. Your nervous tissue is composed of 2 types of cells: 1. Glia – provides structural support, nourishment and insulation for neurons 2. Neurons - receive, integrate and transmit information. They are the basic links that permit communication within the nervous system. - Soma is the body of the neuron. - Dendrites are the parts of the neuron that receive information - The axon transmits signals away from the soma to other neurons, or muscles or glands. - The myelin sheath is the insulating material surrounding the axons. - Terminal buttons are the ends of the axons that secrete chemicals called neurotransmitters. These neurotransmitters serve as messengers that may activate neighboring neurons. - A synapse is the junction where information is communicated between neurons. The points at which neurons interconnect. - Essentially, information is received at the dendrite, is passed through the soma and along the axon, and is transmitted to the dendrites of other cells at meeting points called synapses. The Neuron impulse (when a neuron is stimulated, using energy to send information) - - - - Inactive neurons have a resting potential. This is a negative charge. The neuron at rest is a tiny battery, a store of potential energy. When a neuron activates, it creates an action potential. The neuron’s electrical charge changes and becomes less negative or even positive. This shift travels down the axon. After firing, the neuron must rest. This is the neuron’s absolute refractory period. After the refractory period, the neurons regain a negative charge. Certain drugs, like anesthetics, prevent the neurons from firing. The neurons aren’t able to rest after the refractory period because the positive ions are blocked. Neurons fire their entire potential. This is the All or None Law. Neurons communicate the strength of a stimulus by how fast they fire. A strong stimulus causes neurons to fire more quickly than a weaker stimulus. The Synapse - - - - Remember, the neural impulse functions as a signal. For that signal to have any meaning for the system as a whole, it must be transmitted from the neuron to other cells. This transmission takes place at special junctions called synapses, which depend on neurotransmitters (chemical messengers). Neurons don’t touch one another. The synaptic cleft is the space between a neuron and the terminal buttons of another neuron. Signals have to cross this gap to permit neurons to communicate. When a neuron’s action potential reaches the terminal buttons, they release neurotransmitters. Neurotransmitters transmit information from one neuron to another. Neurotransmitters go to receptor sites on the postsynaptic cell membranes of the receiving cell. The postsynaptic potential (PSP) is created when neurotransmitters combine with receptors. It is a voltage change on the postsynaptic cell membrane. Postsynaptic potentials do not follow the All or none Law. They are graded. An excitatory PSP is a positive voltage shift. This increases the probability that the postsynaptic neuron will fire. An inhibitory PSP is a negative voltage shift. This decreases the probability that the postsynaptic neuron will fire. The neurotransmitters then either become inactive or are returned to the presynaptic neuron through reuptake. Neurotransmitters and behavior - There are many different types of neurotransmitters. Specific neurotransmitters work at specific kinds of synapses. Transmitters cannot bind to just any site on the post synaptic membrane. The binding process acts like lock and key. Specific transmitters can deliver signals only at certain locations on cell membranes. - Agonists are chemicals that mimic the effect of neurotransmitters. Antagonists are chemicals that oppose the effect of neurotransmitters. - Acetylocholine (Ach) is the neurotransmitter found in the motor neurons. Monoamines are neurotransmitters that include dopamine, norepinephrine, and serotonin. Serotonin, for example, helps to regulate sleep. Dopamine is involved in voluntary movement. Abnormalities in levels of monoamines can cause psychological disorders. For example, low levels of norepinephrine and serotonin can cause depression and abnormal levels of dopamine can cause schizophrenia. Drugs like cocaine affect people because they affect the levels of dopamine and norepinephrine. Endorphins are neurotransmitters that reduce pain and produce feelings of exhilaration. They are similar to opiates. Section 2 – Organization of the Nervous System The human nervous system consists of the central nervous system and the peripheral nervous system. The central nervous system - The CNS consists of the brain and the spinal cord. - The spinal cord connects the brain to the peripheral nervous system. - The CNS is protected by cerebrospinal fluid or CSF (to cushion the brain) and the blood-brain barrier (to screen chemicals from the brain). The peripheral nervous system - The peripheral nervous system is made up of all the nerves that lie outside the brain and spinal cord. - The peripheral nervous system is divided into the somatic nervous system and the autonomic nervous system. The somatic nervous system is made up of nerves connected to voluntary muscles and sensory receptors. These nerves are the cables that carry information from receptors in the skin, muscles and joints to the central nervous system and carry commands from the CNS to the muscles. These functions require 2 kinds of nerve fibers. In the somatic nervous system, afferent nerve fibers carry information to the CNS (inward to the CNS from the periphery of the body). Efferent nerve fibers carry information from the CNS (outward from the CNS to the periphery of the body). The autonomic nervous system is made up of nerves connected to the heart, blood vessels and glands. It controls our automatic, involuntary functions that people don’t normally think about, such as heart rate, digestion and perspiration. The autonomic nervous system is divided into the sympathetic division and parasympathetic division. The sympathetic division controls the body’s resources for emergencies, i.e. – releasing adrenaline or withdrawing blood from limbs to the vital organs. It creates the fight or flight response. The parasympathetic division conserves the body’s resources i.e. – slowing heart rate. - - - - - Section 3 – Researching the brain Neuroscientists try to map out the structure and function of the brain. The structure of the brain can be mapped out quite easily by examining and dissecting brains removed from animals or deceased humans. Mapping brain function however, requires a working brain. Therefore special research methods are needed to discover relations between brain activity and behavior. - The electroencephalograph (EEG) measures electrical activity in the brain. Different brain wave patterns are associated with different mental activities. - Lesioning - When people suffer brain damage, they develop lesions on their brains. Neuroscientists can study the effects of these lesions. - Electrical stimulation of the brain (ESB) involves sending electrical signals into parts of the brain to stimulate or activate it. Most ESB research is done on animals, but it is also a routine part of brain surgery. Brain imaging - A computerized tomography (CT) scan involves the use of computer enhanced x-rays of the brain. The brain is x-rayed from many angles to produce an image of the brain. It is used to look for abnormalities in brain structure among people suffering from specific types of mental illness. - A position emission tomography (PET) scan images brain function, not structure like a CT scan. It maps the actual activity in the brain over time. Brain activity is imaged by using radioactive chemicals. - A magnetic resonance imaging (MRI) scan uses magnetic fields to map brain structure and activity at the same time. Section 4 – The Brain The brain can be divided into 3 major regions – hindbrain, midbrain and forebrain. The hindbrain - The hindbrain includes the cerebellum, the medulla, and the pons. The medulla and the pons are part of the brainstem. - The medulla, attached to the spinal cord, controls unconscious functions like circulation, breathing, coughing and sneezing. - The pons (bridge) connects the brainstem with the cerebellum. - The cerebellum (little brain) coordinates movement signals from the forebrain and the senses from the body. It is critical to the coordination of movement and to the sense of equilibrium or physical balance. The midbrain - The midbrain is the top of the brainstem. It is between the hindbrain and the forebrain. - The midbrain deals with senses and movement. It is an important centre for dopamine production. - The reticular formation deals with reflexes, breathing, pain perception and sleep. It is also part of the hindbrain. The forebrain - The forebrain is the most complex part of the brain. It includes the thalamus, hypothalamus, limbic system, and cerebrum. - The thalamus is where all sensory information passes to the cerebral cortex. - - - - - The hypothalamus controls the autonomic nervous system, connects the brain to the endocrine system, and regulates fighting, fleeing, feeding and mating. The limbic system is involved in emotion, memory, and motivation. The limbic system is not well understood. The cerebrum is the largest and most complex part of the human brain. It includes the brain areas that are responsible for the most complex mental activities including learning, remembering, thinking and consciousness itself. The cerebrum is divided into 2 halves called hemispheres – right and left halves of the cerebrum. Each cerebral hemisphere is divided into 4 parts called lobes. To some extent each of these lobes is dedicated to specific purposes. The 4 lobes are: Occipital lobe – at the back of the head includes the cortical area, where most visual signals are sent and visual processing is begun (also called the primary visual cortex) Parietal lobe is forward of the occipital lobe. It includes the area that registers the sense of touch, called the primary somatosensory cortex. The temporal lobe includes primary auditory cortex for auditory processing. The frontal lobe includes the primary motor cortex for movement and the prefrontal cortex for planning, attention, and organizing. Brian Plasticity – refers to the brains ability to change structure and function. Neural wiring of the brain is flexible and constantly evolving. The brains plasticity declined with age. Section 5 – Cerebral laterality Right and left hemispheres of the brain - - - The left hemisphere is better at verbal processing, such as language, speech, reading and writing. The right hemisphere is better at nonverbal processing, such as spatial and musical tasks and visual recognition. Although the left hemisphere is better at verbal processing, the right is also involved. Although the right is better at non-verbal processing, the left is also involved. Each hemisphere’s primary connections are to the opposite side of the body. Thus the left hemisphere controls and communicates with the right hand, right arm, right leg, right eyebrow etc. In contrast, the right hemisphere controls and communicates with the left side of the body. Much has been learned through split-brain research, i.e. research on people who have had brain surgery to cut the corpus callosum. Section 6 – The Endocrine System (our body’s second communication system) - The endocrine system consists of glands that release hormones into the bloodstream to control bodily function, i.e. the pancreas releases insulin to process sugar. - Much of the endocrine system is controlled by the hypothalamus. The pituitary gland, connected to the hypothalamus, releases hormones to stimulate other glands. It is sometimes called the “master gland.” The endocrine system works with the nervous system. Hormones (chemical substances released by the endocrine glands) are also important in physical development. Hormones are similar to neurotransmitters in many ways. Section 7 – Heredity and Behaviour Genetics - Chromosomes are strands of deoxyribonucleic acid (DNA) molecules that carry genetic information. They are in every cell of your body. Genes are DNA segments on chromosomes that are transmitted from parent to child at conception. Each parent contributes 23 chromosomes. Like chromosomes, genes work in pairs. Some genes are dominant, others are recessive. Genotype is a person’s genetic makeup. Phenotype refers to the way a person’s genotype is demonstrated in physical appearance. Polygenic traits require more than two genes, i.e. skin color. Research methods and heredity - In family studies, researchers examine heredity by studying the traits of people who are related to one another. In twin studies, researchers examine heredity by studying the traits of identical twins and fraternal twins. In adoption studies, researchers examine heredity by studying traits of children, their biological parents, and their adoptive parents. Genetic mapping is the current research effort to determine the location and function of all human genes. Nature (heredity) and nurture (environments) are important to development. Evolutionary psychology is based on the theory of evolution and knowledge of genetics and heredity.