Reading Guide for Essay DNA Structure and Replication p. 513 - 518 Name Date Period Directions: Read the essay and answer each question in the space provided beneath it. In the box on the right column, draw a diagram (do not copy from the textbook) to show your understanding of your answer. Question and Answer Space Diagram to show your understanding 1. DNA is required for what three things mentioned in the first sentence of this essay? 2. In all eukaryotic cells, the genetic material consists of ________ _________. These molecules are packaged tightly in what visible structures (to the microscoped eye!)? _______________________ Show the relationship between these two answers. 3. List how many chromosomes you would find in a sperm cell (which has only half the number of chromosomes as any other body cell), a red blood cell, and a stomach lining cell. Draw the 3 types of cells and draw the chromosomes in their nuclei (yes, all of them!) Sperm (a type of gamete) Cell ________________ chromosomes Red Blood Cell __________________ chromosomes Stomach Lining _________________ chromosomes 4. Each chromosome consists of ____________ DNA molecule(s) and ________________ 5. Observe Figure E12.2 on p. 514 and read the caption below. What purpose do nucleosomes serve? 6. Observe Figure E12.4a. Why is DNA appropriately called a “double helix”? What is “double” about it? What is “helical” about it? 7. If DNA is a polymer, what are the monomers that make it up? 8. Separation of the double helix into two single strands is crucial to replication. How is it possible to separate the two strands? 9. Read the explanation of DNA replication (copying of a DNA molecule to form new strands) on p.517 and summarize in 1-2 sentence s how replication works. Use all of the following terms and underline each when used: nucleotide, unzip, enzyme(s), strand(s) Extra Credit: Conduct web research to understand how semi-conservative replication occurs. Explain how it works and draw an image to help others understand how it works and why it’s named appropriately. Use the back if you need more room. 1 2