EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Volume 62 Number 3 March 2006 Clinical Trials Pharmacogenetics Pharmacoepidemiology and Prescription Macedo A, Farre M, Bafios J-E: A metaanalysis of the placebo response in acute migraine and how this response may be influenced by some of the characteristics of clinical trials 161 Vormfelde SV, Sehrt D, Bolte D, Pahl S, Tzvetkov M, Brockmoller J: Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers 195 Silvani MC, Motola D, Poluzzi E, Bottoni A, De Ponti F, Vaccheri A, Montanaro N: Gastrointestinal problems and concomitant medication in N5AID users: additional findings from a questionnaire-based survey in Italy 235 Harenberg J, Joerg I, Weiss C; Incidence of recurrent venous thromboembolism of patients after termination of treatment with ximelagatran 173 Pharmacokinetics and Disposition Yang T-L, Chen M-F, Xia X, Luo B-L, Li Y-J: Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia 179 Polasek TM, Miners JO; Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate 203 Guitton E, Montastruc J-L, Lapeyre-Mestre M, The French Network of Pharmacovigilance Centres: Influence of HCV or HBV coinfection on adverse drug reactions to antiretroviral drugs in HIV patients 243 Pharmacodynamics Swart EL, Zuideveld KP, de Jongh J, Danhof M, Thijs LG, Strackvan Schijndel RMJ: Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients 185 Sugimoto K-i, Araki N. Ohmori M, Harada K-i, Cui Y, Tsuruoka S, Kawaguchi A, Fujimura A; Interaction between grapefruit juice and hypnotic drugs: comparison of triazolam and quazepam 209 Kajosaari LI, JaakkolaT, Neuvonen PJ, Backrnan JT: Pioglitazone, an in vitro inhibitor of CYP2C8 and CYP3A4, does not increase the plasma concentrations of the CYP2C8 and CYP3A4 substrate repaglinide 217 Madabushi R, Frank B, Drewelow B, Derendorf H, Butterweck V: Hyperforin in St. John's wort drug interactions 225 Forthcoming articles in print published online and citable with the DOI {Digital Object Identifier) can be found at springerlink.com Indexed in/abstracted by Current Contents and Index Medicus