European Journal
of Clinical Pharmacology
Volume 64 • Number 11 - November 2008
PHARMACODYNAMICS
Impaired heart rate variability and altered cardiac
sympathovagal balance after antidepressant overdose
W.S. Waring ■ J.Y. Rhee ■ D.N. Bateman ■ G.E Leggett ■ H.
Jamie 1037
Lack of a pharmacokinetic interaction between a new
smoking cessation therapy, varenictine, and digoxin in adutt
smokers
H.M. Faesset ■ A.H. Burstein ■ M.D.Troutman ■ S.A. Willavize ■
K.D. fiohrbacher ■ DJ. Clark 1101
PHARMACOEPIDEM1OLQGY AND PRESCRIPTION
Dose-response effect of serum butyrylcholinesterase
activity after clinical doses of pancuronium
C. Motamed ■ P. Fanen ■ P. Feiss ■ K. Kirov • P. Ouvaldestin 1043
PHARMACOGENETICS
Pharmacogenetic effect of the UGT polymorphisms on
mycophenolate is modified by calcineurin inhibitors
L.A. Johnson ■ W.S. Oetting ■ S. Basu ■ S. Prausa ■ A. Matas ■
PAJacobson 1047
Genetic determinants of methotrexate toxicity in rheumatoid
arthritis patients: a study of polymorphisms affecting
methotrexate transport and folate metabolism
P. Bohanec Grabar ■ D. Logar ■ B. Lestan ■ V. Dolzan 1057
Association of MDR1, CYP3A4*18B, and CYP3A5*3
polymorphisms with cyclosporine pharmacokinetics in
Chinese renal transplant recipients
X.-y. Qiu ■ Z. Jiao ■ M. Zhang ■ L.-j. Zhong ■ H.-q. Liang ■ C.-l. Ma ■ L
Zhang ■ M.-k. Zhong 1069
Off-label and unlicensed drug utilization in hospitalized
children in Fortaleza, Brazil
D.B. Santos - A. Clavenna ■ M. Bonatt ■ H.LL Coelho 1111
The association between use of cardiovascular drugs and
antidepressants: a nationwide register-based study
K.Johneil-J. Fastbom 1119
Prescription drug use during pregnancy: a populationbased study in Regione Emilia-Romagna, Italy
J.J. Gagne ■ V. Maio ■ V. Berghella ■ D.2. Louis ■ J.S. Gonnella 1125
LETTERS TO THE EDITORS
Quantitative assessment of hepatic blood flow using
intravenous indocyanine green
J.D. Ma ■ A.N. Nafziger ■ W. Mylott ■ D.B. Haughey ■ Ml. Rocci Jr. •
J.S. Bertino Jr. 1133
Dual drug interactions via P-glycoprotein (P-gp)/ cytochrome
P450 (CYP3A4) interplay: recent case study of oral
atorvastatin and verapamil
N.R.Srinivas 1135
PHARMACOKINETiCS AND DISPOSITION
Oral absorption of propiverine solution and of the
immediate and extended release dosage forms: influence of
regioselective intestinal elimination
K. May ■ T. Giessmann ■ D. Wegner ■ R. Oertel ■ C. Modess ■
S.Oswald- M. Braeter-W. Siegmund 1085
Further articles can be found at www.springerlink.com Indexed
in/abstracted by Current Contents and IndexMedicus.
Pharmacokinetics and penetration of linezolid into inflamed
soft tissue in diabetic foot infections
J. Majcher-Peszynska ■ G. Haase ■ M. SaR ■ R. Mundkowski ■ A.
Pietsch ■ S. Klammt ■ W. Schareck ■ B. Drewelow 1093
Instructions for Authors for EurJClin Pharmacol are available at
www.springer.com/00228.