1 st Symposium on the Neurovirology and Neuroimmunology of Schizophrenia and
Bipolar Disorder
November, 1995
VIRUSES AND PSYCHIATRIC DISEAES—DOES THE CONNECTION MAKE
SENSE?
Robert H. Yolken, Stanley Neurovirology Laboratory, Johns Hopkins University
VIRAL TRANSCRIPTION FACTOR RNAs ARE DIFFERENTIALLY
EXPRESSED IN THE BRAINS OF INDIVIDUALS WITH SCHIZOPHRENIA
Frances Yee, Stanley Fellow, Johns Hopkins University
METABOLITES OF CLOZAPINE INHIBIT THE REPLICATION OF
NEUTOTROPIC VIRUSES
Lorraine V. Brando, Stanley Neurovirology Laboratory, Johns Hopkins University
A COMPARISON OF CYTOKINE TRANSCRIPTS FROM SELECTED BRAIN
AREAS BETWEEN INDIVIDUALS WITH SCHIZOPHRENIA AND CONTROLS
Linda Bobo, Stanley Neurovirology Laboratory, Johns Hopkins University
BRAIN LIBRARIES INDICATE DIFFERENTIAL RNA EXPRESSION IN
SCHIZOPHRENIA AND BIPOLAR DISEASE
Nancy Johnston, Stanley Fellow, Johns Hopkins University
ASSESSMENT OF GENOMIC DIFFERENCE BETWEEN LIVER AND BRAIN
OF A SCHIZOPHRENIC PATIENT
Naderah Jafari, Stanley Fellow, Johns Hopkins University
INFECTION OF NEURAL CELLS WITH BRAINS FROM INDIVIDUALS WITH
SCHIZOPHRENIA
Indre Dé, Stanley Fellow, Johns Hopkins University
ANALYSIS OF GENOMIC DNA FROM PATIENTS WITH SCHIZOPHRENIA
Yeping Sun, Stanley Fellow, Johns Hopkins University
EFFECTS OF VIRUSES ON LIMBIC SYSTEM NEURONS AND
NEUROTRANSMITTERS: IMPLICATIONS FOR SCHIZOPHRENIA AND
BIPOLAR DISORDER
Krister Kristensson, Department of Neurosciences, Karolinska Institute, Stockholm,
Sweden
RETROVIRAL ANTIBODIES IN SCHIZOPHRENICS: POSSIBLE
IMMUNOMODULATION BY PSYCHOTROPIC DRUGS
Darrenn J. Hart, Tulane University School of Medicine

MATERNAL INFLUENZA, OBSTETRIC COMPLICATIONS AND
SCHIZOPHRENIA
Padraig Wright, Pfizer Central Research, UK
MAPPING OF A HERPES SIMPLEX VIRUS GENETIC ELEMENT INVOLVED
IN NEUROVIRULENCE AND NEUROINVASIVENESS
Jeng-Yang Ling, Baylor College of Medicine
IgM ANTIBODIES TO EIGHT COMMON NEUROTROPIC VIRUES IN THE
SERUM SAMPLES OF SCHIZOPHRENIC PATIENTS AND CONTROLS FROM
SOUTH INDIA
V. Ravi, NIMHNS, India
HSV-1 IN BRAIN: AN ENVIRONMENTAL RISK FACTOR IN ALZHEIMER’S
DISEASE
Ruth F. Itzhaki, University Manchester, UK
RETINOIC ACID RESPONSE ELEMENT DNA MOTIFS IN VIRUSES MAY
AFFECT RETINOID CASCADE IN SCHIZOPHRENIA
Ann B. Goodman, Nathan S. Kline Institute
RELATIONSHIP OF ANTI-STREPTOCOCCAL AND ANTI-NEURONAL
ANTIBODIES IN PATIENTS WITH TOURETTE’S SYNDROME AND
OBSESSIVE COMPULSIVE DISORDER
Daniel M. Tucker, Yale University School of Medicine
STATE DEPENDENT IMMUNE DISTRUBANCES IN SCHIZOPHRENIA
Daniel P. van Kammen, Department of Veterans Affairs Medical Center, Pittsburgh, PA
PREDICTION OF RELAPSE FROM CHANGES IN CYTOKINE AND ANTIBOY
PRODUCTION IN SCHIZOPHRENIA
Rohan Ganguli, Western Psychiatric Institute and Clinic
EVALUATION OF 6 MEASURES OF CENTRAL NERVOUS SYSTEM IMMUNE
ACTIVATION IN CSF OF PATIENTS WITH SCHIZOPHRENIA
George R. Heninger, Yale University School
ACUTE PHASE PROTEINS IN AFFECTIVE ILLNESS
Mady Hornig-Rohan, Depression Research Unit, University of Pennsylvania
ENUMERATION OF CD34 + HEMATOPOIETIC STEM CELLS IN
SCHIZOPHRENIC INDIVIDUALS RECEIVING CLOZAPINE
Henrietta Kulaga, National Institute of Mental Health
THE IMMUNE SYSTEM ALTERATIONS IN PSYCHIATRIC DISORDERS: THE
CAUSES OF APPEARANCE AND THE MECHANISMS OF DEVELOPMENT

Galina Kolyaskina, National Mental Health Research Center, Russia
OVERVIEW OF THE BIOLOGY OF BORNA VIRUS AS APPLIED TO
PSYCHIATRIC DISEASES
Kathryn Carbone, The Johns Hopkins University School of Medicine, Division of
Infectious Diseases, Baltimore, MD
EXPERIMENTAL BORNA DISEASE AS A MODEL FOR IMMUNE-MEDIATED
ABNORMALITIES IN THE BRAIN
Lothar Stitz, Institut für Virologie, Germany
SEVERE NEUROLOGICAL SYMPTOMS IN MICE INFECTED WITH BORNA
DISEASE VIRUS
Peter Staeheli, University of Freiburg, Germany
QUANTITATIVE CORRELATION OF VIRAL INDUCED DAMAGE TO THE
HIPPOCAMPUS AND SPATIAL LEARNING AND MEMORY DEFICITS
Kathryn Carbone, The Johns Hopkins University School of Medicine, Division of
Infectious Diseases, Baltimore, MD
PREFRONTAL CORTEX DYSFUNCTION IN RATS INFECTED WITH BORNA
DISEASE VIRUS
W. Ian Lipkin, University of California, Irvine
DETECTION, ISOLATION AND MOLECULAR CHARACTERIZATION OF
HUMAN BVD
Daniel Gonzalez-Dunia, The Scripps Research Institute
SCHIZOPHRENIA AND BORNA DISEASE-CLINICAL RELATIONSHIPS IN A
MONOZYGOTIC TWIN STUDY COHORT
Royce W. Waltrip II, Maryland Psychiatric Research Center
VIRUS INFECTION OF NEURONS, DISORDERED CNS FUNCTION AND
RESULTANT NEUROPSYCHIATRIC DISEASE
Michael B. A. Oldstone, The Scripps Research Institute
THE IMMUNOPATHOGENESIS OF VIRUS-INDUCED MYOCARDITIS
Noel R. Rose, The Johns Hopkins University
VIRAL MODELS FOR PERSISTENT NEUROLOGICAL INFECTION
Diane Griffin, The Johns Hopkins University
GEOGRAPHIC CORRELATION OF SCHIZOPHRENIA AND IXODES TICK-
BORNE VIRUSES
James S. Brown, M.D., U.S Military Academy

SIMULTANEOUS ANALYSIS OF MULTIPLE DNA SUSPECTS FROM TWINS
DISCORDANT FOR SCHIZOPHRENIA
Cassandra L. Smith, Boston University
CALCIUM DYSREGULATION IN MAJOR MOOD DISORDERS
Martha M. Coetzee, Uniformed Services University of the Health Sciences
VIRAL RESEARCH IN SCHIZOPHRENIA: PHENOMENOLOGICAL
CONSIDERATIONS
William T. Carpenter, University of Maryland School of Medicine
A NEW FOAMY RETROVIRUS FROM AN ORANG-UTAN WITH
ENCEPHALOPATHY
Myra O. McClure, St. Mary’s Hospital Medical School, UK
VIRUS-INDUCED PATHOLOGY IN THE DEVELOPING HIPPOCAMPUS MAY
INVOLVE DISRUPTION OF INHIBITORY CIRCUITS
Brad D. Pearce, Emory University School of Medicine
ALTERED BRAIN FYN KINASE IN A MURINE AIDS
Yoshitatsu Sei, NIDDK, NIH
SURROGATE MARKERS’ FOR ENCEPHALOPATHY IN THE SIV-INVECTED
RHESUS MONKEY
Lee E. Eiden, National Institute of Mental Health
ATTEMPTS TO PASSAGE A TRANSMISSABLE GROWTH AGENT FROM
CSF OF SCHIZOPHRENIC PATIENTS TO NEONATAL MICE
Janice R. Stevens, Oregon Health Sciences University
LOCALIZATION OF VIRAL MESSAGE IN BRAINS OF CATS EXPOSED
POSTNATALLY TO BOVINE VIRAL DIARRHEA VIRUS
Susan E. Bachus, National Institute of Mental Health
DECREASED LEVELS OF A LIPID IN THE BRAIN FRONTAL LOBE IN
PATIENTS WITH SCHIZOPHRENIA
Subrato Chatterjee, The Johns Hopkins University School of Medicine
POSTERS
POSSIBLE SUPPRESSION OF HERPES SIMPLEX VIRUS INFECTIONS WITH
LITHIUM CARBONATE
Jay D. Amsterdam, Greg Maislin, University of Pennsylvania Medical Center

VIRAL ETIOLOGY AND SEASONALITY OF SCHIZOPHRENIC BIRTHS IN
BARBADOS
Ram Rao Malesu, K. McKenzie, R. Murray, Institute of Psychiatric, Genetics Section,
London
A 7-YEAR PROSPECTIVE STUDY OF LONG-TERM LITHIUM EFFECT ON
AFFECTIVE AND LABIAL HERPES RECURRENCES IN BIPOLAR PATIENTS
Janusz K. Rybakowski and Jay D. Amsterdam – Department of Adult Psychiatry,
University of Medical Sciences, Poland and University of Pennsylvania Medical Center
SEROEPIDEMIOLOGICAL STUDIES OF PRENATAL VIRAL INFECTION
AND ADULT SCHIZOPHRENIA
Alan S. Brown, New York State Psychiatric Institute