2nd Annual Young Investigator Symposium on Genomics and Bioinformatics Friday, September 5, 2008 Tilghman Auditorium, Turner Concourse Johns Hopkins School of Medicine Sponsored by the Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health 08:30AM-9:00AM Breakfast (provided) + Welcome 09:00AM-10:00AM Introductory Speaker: Jonathan Pevsner “Genomics, Bioinformatics and the Revolution in Biology” 10:00AM-10:45PM Kathleen Burns: “Comprehensive transposon mapping in the human genome” 10:45AM-11:30PM Rob Scharpf: “Genome-scale estimation of copy number and inference” 11:30AM-12:15PM Bo Wen: “Heterochromatin blocks distinguish differentiated from embryonic stem cells” 12:15PM-02:00PM Lunch (provided) + Poster Session (see next page). 02:00PM-02:45PM Parminder Mankoo: “Somatic Mutations in PIK3CA” 02:45PM-03:30PM Donald William Parsons: “Large-scale mutational analyses of human cancers: Lessons learned from sequencing cancer genomes” 03:30PM-04:30PM Keynote Speaker: Steven Salzberg “Assembling Genomes from Next-Generation Sequencers” 5PM-onward Drinks and Dinner provided at the Waterfront Hotel in Fell's Point (1710 Thames Street). 2nd Annual Young Investigator Symposium on Genomics and Bioinformatics Poster Session Hector Corrada Bravo, Johns Hopkins Dept. of Biostatistics: “Estimating Tree-Structured Covariance Matrices via Mixed- Integer Programming with an Application to Phylogenetic Analysis of Gene Expression” Donavan Cheng, Johns Hopkins University: “An Alignment Independent Algorithm for Motif Discovery using Sequence Conservation” Supriyo De, Gene Expression and Genomics Unit, National Institute on Aging, National Institutes of Health: “Systems Analysis of Common Multigenetic Human Diseases” Julia C. Engelmann, Johns Hopkins University: “Genotyping, copy number analysis and allele-specific methylation with SNP6.0 Affymetrix arrays” Adam Lee, University of Maryland: “A framework for discovering associations from the annotated biological web” Jimmy Lin, Johns Hopkins University: “Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses” Yan Qi, Johns Hopkins University: “Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions" Matthew Ritchie, Department of Oncology, University of Cambridge: “Measuring allele-specific expression using Illumina's GoldenGate platform” Balaji Veeramani, Department of Biomedical Engineering, Johns Hopkins University: “Metabolic flux correlations, genetic interactions and disease”