FOCUS ON GENOMICS, PROTEOMICS AND CLINICAL TRIALS NOVEMBER 15-16, 2001 BETHESDA, MD GENE EXPRESSION IN COMPLEX NEUROPSYCHIATRIC DISORDERS Sabine Bahn, Cambridge University MICROASSARY ANALYSIS OF THE STANLEY BRAIN COLLECTION Pamela Sklar, Whitehead Institute PRELIMIARY SCREENING OF GENE EXPRESSION IN SCHIZOPHRENIA cDNA MICROARRAY Marquis Vawter, University of California, Irvine SCHIZOPHRENIA AS A DISEASE OF THE SYNAPSE Karoly Mirnics, University of Pittsburgh RNA PROFILING IN NEUROPSYCHIATRIC AND NEURODEGENERATIVE DISORDERS Allen Fienberg, Rockefeller University TECHNOLOGIES AND STRATEGIES FOR STUDYING GENE EXPRESSION CHANGES IN PSYCHIATRIC DISEASE C. Anthony Altar, Psychiatric Genomics, Inc., Gaithersburg, MD ASSEMBLY OF A NEUROPSYCHIATRIC cDNA ARRAY Kevin Becker, National Institutes of Health PROFILING THE BRAIN WITH MICROARRAYS: DATA ANALYSIS ISSUES Simon Lin, Duke University GENE EXPRESSION CHANGES FOLLOWING NEONATAL VENTRAL HIPPOCAMPAL LESIONS Graham Wood, Douglas Hospital Research Center, McGill University THE HUMAN BRAIN PROTEOME: INITIAL RESULTS FROM THE HUMAN PROTEIN INDEX PROJECT N. Leigh Anderson, Large Scale Biology PROTEINCHIP PROTEOMICS FOR PROFILING OF NEUROPSYCHIATRIC DISEASE Eric Fung, Ciphergen Biosystems TRANSLATIONAL PERSPECTIVES ON THE RATIONALE AND STRATEGIES FOR NOVEL DRUG DEVELOPMENT Jeffrey Lieberman, University of North Carolina at Chapel Hill POSSIBLE ROLE OF MYELIN RELATED GENES IN SCHIZOPHRENIA Ken Davis, Mount Sinai School of Medicine DEVELOPING MEDICATION STRATEGIES FOR RELAPSE PREVENTION IN SCHIZOPHRENIA John Kane, Hillside Hospital-A division of Long Island Jewish Medical Center LOOKING ELSEWHERE: NEW TARGETS AND TREATMENTS FOR BIPOLAR DISORDER Bruce Cohen, McLean Hospital PROSPECTS FOR NEW AND NOVEL THERAPEUTIC APPROACHES TO MOOD AND ANXIETY DISORDERS Dennis Charney, National Institute of Mental Health TARGETS FOR DEVELOPMENT OF NOVEL ANTIDEPRESSANT AND MOOD STABILIZER; GSK-3 AND NEUROTROPHIC FACTORS SIGNALING CASCADES Husseini Manji, National Institutes of Mental Health IN VIVO BRAIN IMAGING AND DRUG DEVELOPMENT Clinton Kilts, Emory University ANTI-INFAMMATORY AGENTS FOR SCHIZOPHRENIA Norbert Müller, Ludwig Maximilians Universität München, Germany PHARMACO GENOMIC STRATEGIES FOR NEW DRUG DEVELOPMENT Anil Malhotra, Hillside Hospital- A Division of Long Island Jewish Medical Center RELEVANCE OF ANTIBIOTIC STUDIES TO ETIOLOGICAL HYPOTHESES Robert Yolken, Stanley Division of Developmental Neurovirology, Johns Hopkins University STRATEGIES FOR SELECTING TARGETS FOR DRUG DEVELOPMENT IN SCHIZOPHENIA Carol Tamminga, Maryland Psychiatric Research Center, University of Maryland REELING IN PSYCHOSIS John Davis, University of Illinois at Chicago COMPENSATORY PROCESSES MAINTAINING FUNCTION AFTER GENE DELETION OF DA RECEPTOR SUBTYPE INDICATE NOVEL DRUG TARGETS John Waddington, Royal College of Surgeons in Ireland Medical School POSTERS PRELIMINARY EXAMINATION OF REGIONAL DISTRIBUTION OF HUMAN CORONOVIRUS RNA IN POST MORTEM HUMAN BRAIN Arlene Collins, State University of New York at Buffalo PRELIMINARY EVALUATION OF VIRUSES AND INTRACELLULAR BACTERIA STATUS IN URBAN CATS AND THEIR RELATIONSHIP WITH DEVELOPMENT OF SCHIZOPHRENIA IN HUMANS Reza Firouzi, Laboraiare des Deficits Immunitaires, France CLONALLY EXPANDED T CELLS ARE PRESENT IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION Emilia Oleszak, Temple University School of Medicine MICROARRAY STUDIES – AN INTEGRATIVE PLATFORM FOR CASECONTROL STUDIES AND ANIMAL MODELS OF SCHIZOPHRENIA Francois Feron, Queensland Center for Schizophrenia, Australia ALTERED LEVELS OF REELIN AND ITS ISOFORMS IN SCHIZOPHRENIA AND MOOD DISORDERS S. H. Fatemi, University of Minnesota TGF-BETAL EXPRESSION IN SUBJECTS WITH MOOD DISORDERS AND LITHIUM-TREATED RATS L. Trevor Young, McMasters University, Ontario ON THE ROLE OF INFECTION IN SCHIZOPHRENIA AND OTHER MENTAL ILLNESSES-HISTORICAL PERSPECTIVES AND THERAPEUTIC IMPLICATIONS S. H. Shakman, Institute of Science, California DEVELOPMENT OF BROADLY AMPLIFYING REAL TIME PCRS FOR DETECTION AND QUANTIFICAITON OF RETROVIRAL NUCLEIC ACID Jonas Blomberg, Uppsala University, Sweden GENOMIC DNA STABILITY AND SCHIZOPHRENIA IN TWINS Cassandra L. Smith, Boston University RETROVIRUS REACTIVITY OF PERINATAL SERA FROM MOTHERS WHOSE CHILDREN DEVELOPED SCHIZOPHRENIA Erik P. Lillehoj, University of Maryland ARE HIGH TITERS OF ANTIBODIES AGAINST CYTOMEGALOVIRUS IN SCHIZOPHRENIA ASSOCIATED WITH BETTER OUTCOME TO ANTIINFLAMMATORY THERAPY? Norbert Müller, Ludwig Maximilians Universität München, Germany TNF-ALPHA POLYMORPHISM G308A MAY PROJECT FROM CYTOMEGALOVIRUS INFECTION IN SCHIZOPHRENIA Norbert Müller, Ludwig Maximilians Universität München, Germany DEFICIENT CALCIUM-DEPENDENT NITRIC OXIDE SYNTHASE ACTIVITY IN THE PREFRONTAL CORTEX OF SCHIZOPHRENIA AND DEPRESSION Guoqiang Xing, Psychology Department, USUHS, Bethesda, MD