Simon David Henry HOLT MA MB BChir FRCS Date of Birth Place of birth Nationality GMC registration 16 July 1951 Blantyre, Malawi British Citizen Full No 2308085 I am established Consultant General Surgeon running a Breast Unit which diagnosed and treated 260 new breast cancers each year. I have extensive experience in breast ultrasound, guided biopsy and breast reconstruction in addition to all the usual skills expected of a breast surgeon. As Postgraduate Organiser for the Prince Philip Hospital for 10 years from 1991, surgical education supervisor and an undergraduate tutor I have extensive teaching experience. As the current Chairman of the South West Wales Breast Cancer Network, past chairman of the Dyfed-Powys Surgical network and Trust Lead for Cancer Services, I have a wide experience in NHS administration. I have a particular interest in emerging technologies, such as computing, imaging and genetics. I regularly attend local, national and international meetings. All my clinical activity figures are available for audit using the BASO/Canisc databases. Education: School Jan 65 to Dec 69 University Oct 70 to Jun 73 Ardingly College, Haywards Heath, Sussex 12 O levels 4 A levels Mathematics B Physics A Chemistry A with distinction Biology C Kings College, Cambridge Senior Scholar in Medicine First class in parts 1A and 1B Medical Sciences BA in Pathology Jun 73 Medical School Sep 73 to Jun 76 University College Hospital, London Prize in Obstetrics and Gynaecology Medical degree Jun76 Cambridge University Distinction in Surgery Fellowship Primary FRCS (London) Jun 79 Final Fellowship (Edinburgh) Oct 81 Accreditation Royal College of Surgeons, London Oct 87 Postgraduate Appointments: House Physician: Sep 76 to Feb 77 University College Hospital To Dr Stokes and Dr Sarner General Medicine and Gastroenterology House Surgeon: Mar 77 to Aug 77 Northwick Park Hospital, Harrow To Mr A G Cox General Surgery and Surgical Gastroenterology Accident and Emergency: Whipps Cross Hospital Aug 77 to Mar 78 To Dr V Dallos General Accident and Emergency Medicine General Practice: May 78 to Nov 79 RAF Benson, Oxfordshire Responsibility for 1100 forces personnel and their families with special duties to The Queen's Flight Surgical SHO: Nov 79 to Apr 80 Jan 81 to Dee 81 RAF Hospital, Nocton Hall, Lincoln To Gp Capt Williams and Wg Cdr Clarke General and Emergency Surgery Apr 80 to Nov 80 To Wg Cdr Murphy General and Emergency Orthopaedics Nov 80 to Jan 81 Musgrave Park Hospital, Belfast, Northern Ireland To Lt Col K Stevens General and Emergency Surgery Surgical Registrar: Jan 82 to Sep 83 RAF Hospital, Wegberg, Germany To Wg Cdr 1 B Tiwari General and Emergency Surgery Senior Registrar: Sep 83 to Sep 84 Peterborough District Hospital, Cambridgeshire To Mr Young, Mr Hall, Mr Kent, Mr Turner and Mr Holmes. Subspecialty and Emergency General Surgery Oct 84 to Sep 85 The Cade Unit, RAF Hospital, Halton, Buckinghamshire To Air Cdr R Jones and Wg Cdr M Ayres Specialist Oncology and General and Emergency Surgery Oct 85 to Sep 86 St Thomas' Hospital, London To Mr B Jackson and Mr J Nichols Specialist Gastroenterology and General Emergency Surgery Oct 86 to Sep 87 RAF Hospital, Wroughton, Swindon, Wiltshire To Gp Capt M Mahony and Wg Cdr B Morgans Specialist Gastroenterology, Urology and Emergency General Surgery Consultant Surgeon: Consultant Surgical Oncologist Sep 87 to Aug 90 The Cade Unit, RAF Hospital, Halton and Honorary Consultant Surgeon at The Westminster Hospital, London. Aug 90 to present Consultant Surgical Oncologist The Prince Philip Hospital, Llanelli Consultant Surgeon to Breast Test Swansea Offices held: 1. President of Kings College Rowing Club, Cambridge 1972-73 2. Deputy President of The Officers Mess, RAF Nocton Hall 1978-79 3. Deputy Clinical Tutor, RAF Hospital Wegberg 1980-81 4. Membership Secretary to The Military Surgical Society 1986-90 5. Forces Representative to The Association of Surgeons in Training 1987-89 6. Committee Member of The United Services Section of The Royal Society of Medicine 1988-90. 7. Clinical Tutor, RAF Hospital Halton 1988 - 1990 8. Chairman of the Audit Committee, RAF Hospital Halton 1989-1990 9. Postgraduate Organiser, Prince Philip Hospital, Llanelli 1991 - 2000 10. Chairman of the Audit Committee, Prince Philip Hospital, Llanelli 1991 to 1995 and member of the committee since 11. Member of the Clinical Effectiveness Group, Prince Philip Hospital, Llanelli, 1996 – 1999. 12. Chairman of the Dyfed-Powys Surgical Network 2001- 2003 13. Team leader in Surgery, Prince Philip Hospital, Llanelli, 2001 to 2004 14. Surgical Educational Supervisor, Prince Philip Hospital, Llanelli 1999 to present 15. Teacher on the ALERT course 2000 – present. 16. Chairman of The South West Wales Breast Cancer Network 2008 – present 17. Cancer Services Lead for Hywel Dda Trust Board – Nov 2010 - present Publications 1. Holt S D H, Howell G P, Tiwari I B. Phenolisation as an adjunct to Zadik's procedure for ingrowing toenail and onychogryphosis. Journal of The Royal College of Surgeons of Edinburgh 1987; 32: 228-229 2. Holt S D H. Terrorism, hostage-taking and the Stockholm syndrome. Proceedings of The Director General Medical Services Symposium 1985; 83-95. (Classified restricted. General publication denied. 3. Holt S D H, Howell G P, Tiwari I B. Biliary peritonitis following the removal of a Ttube. Journal of The Royal Army Medical Corps 1987; 133: 155. 4. Howell G P, Holt S D H, Tiwari I B. Candida septicaemia and abscess formation following multiple injuries and of the stomach. Journal of The Royal Army Medical Corps 1988; 134: 74-75. 5. Holt S D H. Phenolisation as an adjunct to Zadik's procedure for ingrowing toenail and onychogryphosis. Letter to Journal of the Royal College of Surgeons of Edinburgh 1988; 33: 48. 6. Jones D J, Langstaff R J, Holt S D H, Morgans B T. The value of cystourethroscopy in the investigation of haematuria in the adult male under 40. British Journal of Urology 1988; 62: 541-545. 7. Nichols R J, Holt S D H, Lubowski D Z. Restorative proctocolectomy with ileal reservoir. Comparison of two-stage versus three-stage procedures and an analysis of risk factors that might affect outcome. Diseases of the Rectum and Colon 1989; 32, 342-347. 8. Holt S D H. Surgical aspect of sepsis in acute renal failure. Chapter in "Acute Renal Failure Update 1989," edited Rainford D J, Sweny P. Farrand Press, London 1990. 9. Jones D J, Holt S D H, Surtees P, Coptcoat M J, Davidson D J. A comparison of danazol and placebo in the treatment of adult idiopathic gynaecomastia: the results of a double blind randomised study of 55 patients. Annals of the Royal College of Surgeons of England 1990; 72 (5):296-8. 10. A Deshpande, T Garud, SD Holt, GM Le, CDO'Malley et al. Core biopsy as a tool in planning the management of invasive breast cancer.
World J Surg Oncol, 2005 11. Breast Cancer Management in the over 70s. Kannan RY, Khawaja S, Sumrein H, Huws A, Shariaha YM, Holt SDH. BIT Life Sciences’ 3rd Annual World Cancer Congress, Shanghai, April 2010. 12. Oncotype Dx™ in Early Breast Cancer: First UK Prospective Trial. G Bertelli, D Pudney, M Rolles, M Moe, E Brinkworth, S Whelan, S Khawaja, S Holt. National Cancer Research Institute Cancer Conference, Liverpool, November 2010. 13. Gene expression analysis to detect sentinel lymph node involvement. A review of our first 100 cases. Sumrein H, Kawaja S, Shariaha Y, Holt SDH. 13th Milan Breast Cancer Conference, Jun 2010 14. Oncotype Dx versus Notting prognostic index in assessing patients for chemotherapy for breast Cancer. G Bertelli, D Pudney, M Rolles, M Moe, E Brinkworth, S Whelan, S Khawaja, S Holt. St Gallen European Breast Cancer Conference, Mar 2011. 15. The Role of Pre-Operative CT Staging in Determining the Sentinel Lymph Node Status. Saira Khawaja, Ramesh Kannan, Haythem Sumrien, Anita Huws, Yousef Sharaiha, Simon Holt. St Gallen European Breast Cancer Conference, Mar 2011. 16. Digital Breast Tomosynthesis. Y Shariaha, S Khawaja, A Huws, K Nadi, D Premawhadana, S Holt. Association Of Breast Surgeons Meeting, Manchester 2011. Major Papers Presented 1. Hostage-taking and the Stockholm syndrome. Military Surgical Society, Berlin, 1983. 2. Limb trauma and renal failure. Travelling Surgeons Club, RAF Halton, 1985. 3. Interrogation and torture. Getting at the truth? First International Meeting of The Military Surgical Society. Paris 1986. 4. The surgical indications for enteral and parenteral nutrition. Conference on enteral and parenteral feeding, Swindon, 1987. 5. The surgical aspects of the treatment of acute renal failure. International Symposium on acute renal failure, Royal Free Hospital, London, 1989. 6. Restorative proctocolectomy: techniques and complications. Tri-service Surgical Meeting, Institute of Naval, Gosport, 1989. 7. Vasectomy. A guide to patients considering sterilisation. Director General Medical Services (RAF) RAF Halton, Aylesbury, 1989. 8. A complete audit of 5 year survival after surgical treatment for breast cancer for the years 1993 – 1995 stratified by Nottingham prognostic index. Conversazione, Singleton Hospital, Swansea, 1994. 9. Argon diathermy and blood loss at mastectomy. Conversazione, Singleton Hospital, Swanseaa, 1994. 10. Medicine Meets Virtual Reality. A Guide for Non-Nerds. Invited Lecture at The Association of Clinical Tutors, various other venues in the UK. 11. What risk? An evaluation of risk associated with environmental pollution. Invited lecture Prince Philip Hospital. 12. The Human Genome in Five Easy Chapters. Invited lecture University of Malaya, Kuala Lumpur 2000. 13. Technical Developments and the Future Diagnosis and Treatment of Breast Cancer. Various venues including The University of Malaya. Kuala Lumpur. 2001 14. RTPCR intraoperative Sentinel nodes analysis. A clinical and economic analysis of the first 70 cases. All Wales Breast Cancer Meeting, Cardiff 2009. 15. Treating breast cancer in the over 70’s. A review of 150 cases. . All Wales Breast Cancer Meeting, Cardiff 2009, also to be presented as a poster at BIT World Breast Cancer Conference, Shanghai, May 2010. 16. Metasin: A Novel Rapid RT-PCR Assay for the Analysis of Sentinel Lymph Nodes from Patients with Breast Cancer, in the Intra-Operative Setting: Analysis of the First 1000 Cases. Al-Ramadhani S, Balaraman P, George D, Holt S, SUNDARESAN, V , et al. Ghent Pathology Conference 2011. I am the Principle Investigator of a £300,000 trial looking at the treatment and economic impact of routine Oncotype Dx (gene expression analysis of breast cancers). Medical Courses, Conferences, and Workshops attended: 1. Introductory Medical Officers Aviation Medicine Course, RAF Farnborough 1977. 2. Final Fellowship Course, Whipps Cross Hospital 1981. 3. Orthopaedic Workshop, RAF Halton 1981 (Demonstrated 1985). 4. Anastomosis Workshop, RAF Halton 1982. 5. War Surgery Course, Royal Army Medical College 1982 6. RAF Winter Survival School, Bad Kohlgrub, Germany 1982 7. Advanced Aviation Medical Course, RAF Farnborough 1985 8. The Military Surgical Society, founder member and attended all meetings 1981 – 1990. Membership Secretary 1984 – 1990. 9. Association of Surgeons Annual Meetings 1985 and 1986. 10. Association of Surgeons in Training, all Annual Meetings between 1985 and 1989. Forces Representative. 11. Royal College of Surgeons of Edinburgh Annual Meetings 1986, 1987, 1988, 1989. 12. Section of Coloproctology. Regular attendances at meetings 1986-1990. 13. Section of Surgery. Regular attendances at meetings 1986-1990. 14. Royal Society of Medicine, United Services Section. Regular attendances at meetings 1986-1990. Committee Member. 15. Tri-Services Surgical Meetings 1985 and 1989. 16. Director General Medical Services (RAF) Meetings 1985 and 1989. 17. Video in Medicine Conferences 1984, 1985, 1986. 18. Disaster Impact. Annual Meeting of The Society for Psychosomatic Medicine and Research, Royal College of Physicians London 1987 19. Annual Meeting of The National Association Of Clinical Tutors 1989, 1991, 1992, 1993, 1997. 20. Clinical Audit Meeting, The Royal College of Physicians, London, 1989 21. St Marks Teaching Day for The Armed Services 1990. 22. Audit Association meetings 1991,1992, 1993 and 1994. 23. Welsh Postgraduate Organisers Meetings annually 1991 - 2000. 24. Association of Audit Committee Chairmen National Meeting, Birmingham 1994. 25. Welsh Society Meetings 1990, 1991, 1992, 1993 (Co-organiser) 1999 and 2010 26. British Association of Surgical Oncologists Meetings. Most annual audit meetings 1992 – 2009. 27. Welsh Chapter Meetings of The Association of Coloproctologists 1991- 1996 28. Society of Minimally Invasive Therapy International Meeting, Dublin 1993. 29. Laparoscopic Cholecystectomy Training Course, Dundee 1991. 30. Laparoscopic Cholecystectomy Hands-on Training Course, Cardiff 1991. 31. Medicine Meets Virtual Reality, San Diego and Los Angeles, USA 1994, 1996, 1997, 1999, 2002 and 2003. 32. The Malaysian College of Surgeons and The Royal College of Surgeons of Edinburgh, Kuala Lumpur, Malaysia 1993. 33. International Breast Meetings, Nottingham, 1993, 1995, 1997, 2000, 2001. 34. Clinical Effectiveness Workshop, Cardiff 1997. 35. British Association Of Surgical Oncologists study days, Birmingham 1995 - 2010 36. International Congress on Adjuvant Therapy for Early Breast Cancer, St Gallen, Switzerland 1998, 2011 37. The International Workshop on Digital Mammography, Nijmegan, Netherlands 1988 38. Breast Test Wales Induction and Audit days 1992 – 2011 39. San Antonio Breast conferences 2003 and 2006, 2008, 2009 40. Radiological Society of North America, Chicago, 2007, 2008, 2009 . Computer Skills: I am familiar with Word, PowerPoint, Excel and some aspects of Access. I very regularly use the internet for searches and communication. I can use web authoring programs such as Frontpage and Netscape. Fund Raising: Over the last 10 years I have raised £950,000 in funds for the Breast Care Unit. I oversaw the building of the £180,000 first phase of the new breast care facility which was opened in Oct 2001. I have overseen the 8 million pound second phase which is now complete and acknowledged as one of the most advanced in the world. Past Medical History: I have never had more than a few days off work through illness in my career. Legal matters: I have no cases outstanding with the GMC, Coroner or Criminal courts. I have no previous convictions, civil or criminal. Interests: Travel to out of the way places, skiing, squash, modern music and computers. Family: I am married with 2 young children. By my late wife I have two grown up children. We have our own house at In Llanelli Contact: Phone: 01554 783386 Fax 01554 783736 E-mail simon@holtsd.demon.co.uk