IRISH NEUROLOGICAL ASSOCIATION 44th Annual Meeting 8th and 9th May 2008 Jury’s Hotel, Cork. Thursday, May 8th 13.45 Opening of Meeting and Welcome Dr. Niamh Bermingham, President, Irish Neurological Association. Session 1. O1 13.50 Baló’s Concentric Sclerosis with a benign clinical course. Hawkins SA, Rusk L, Gray OM, McKinstry S. O2 14.00 Multiple Sclerosis presenting with Parkinson’s Disease; Coincidence or Cause? Saidha S, Mok T, Butler M, Fanning N, Harrington H. O3 14.10 IVIg – enough punch for the pound? Intravenous immunoglubulin (IVIg) prescription in the Northern Ireland Neurology Department. Doherty K, Devenney E, Fitzpatrick AS, Watt M. O4 14.20 Use Of Complimentary And Alternative Therapies In A Cohort Of Patients With Multiple Sclerosis. Neligan A, Mitten E, O’Mahony E, Merwick A, Ryan AM, Galvin RJ, Sweeney BJ. O5 14.30 OAS in Multiple Sclerosis: not just a haplotype association. Lonergan R, O’Brien M, Costelloe L, Fletcher J, Sweeney C, O’Farrelly C, Hutchinson M, Tubridy N O6 14.40 Replication and Reactivation of BK virus during Natalizumab therapy in Relapsing Remitting Multiple Sclerosis (RRMS) Lonergan R, Costelloe L, Fletcher J, De Gascun CF, Carr M, Coughlan S, Duggan M, Doyle K, Jordan S, Hall WW, Hutchinson M, Tubridy N. O7 14.50 Email Triage of Neurological Referrals Helps Reduce Climate Change. Brown G, Patterson V. O8 15.00 An Audit of Neurology Consults in Haematology-Oncology Services at St. James’s Hospital. Elamin M, Redmond J. O9 15.10 Amnesic syndromes in an acute medical admissions unit: differential diagnosis and outcome. Black N, Forbes F. 15.20 - 15.40 Poster Presentation Viewing 15.40 – 16.00 Tea, Coffee, Posters and Exhibits Session 2. O10 16.00 Hyperactivation of the putamen during a discrimination task in unaffected relatives of patients with familial primary torsion dystonia. Whelan R, Bradley D, Walsh R, Reilly R, Hutchinson M. O11 16.10 Late – onset Ataxia Telangiectasia in a pair of Siblings; A Rare Mutation. Mok TH, Saidha S, Butler M, Harrington H. O12 16.20 A systematic screening of GabaA receptor subunits to identify novel mutations in families with Idiopathic Generalized Epilepsy. Kinirons P, Lachance-Touchette P, Meloche C, Lapointe L, Lortie A, Carmant L, Cossette P O13 16.30 Utilisation and Yield of EMG in the Elderly Population. Dineen J, McNamara B. O14 16.40 EMG in Children’s University Hospital, Temple St, Dublin. Costigan D, Kiely S, Nestor T. O15 16.50 EEG during sleep in healthy neonates within 12 hours of birth Korotchikova I, Boylan GB, Murray DM, Greene BR, Connolly SC, Ryan CA O16 17.00 A Case of Venous Sinus Thrombosis occurring after Lumbar Puncture Spillane J, Saidha S, Galvin R, Fanning N. O17 17.10 An Audit Of The Inadequacy Of Heparinisation Following Coiling Of Cerebral Aneurysms Fenton E, Kelleher MO, McEvoy L, Thornton J, Brennan P, Bolger C O18 17.20 A Year Practice in Interventional Neuroradiology in Beaumont Hospital. O’ Hare A, Go GAG, McErlean A, Breenan P, Thornton J. 17.30 INA Business Meeting (Members Only) 19.30 INA Reception and Dinner, Vertigo restaurant, County Council Office Building. Friday, May 9th Session 3 O19 09.00 Failing to Notice and Failing to Recall: Independent and Co-Morbid Factors in Prospective Memory Failure Clune M, Blanco-Campal A, Carton S, Pender N, O’Brien D, Phillips J, Delargy M, Burke T O20 09.10 Efficacy of Intravenous Tissue Plasminogen Activator for Acute Ischaemic Stroke in Clinical Practice: a Bayesian analysis. O’Rourke K, Walsh C, Kelly P. O21 09.20 Can TIA Clinic Referrals be Triaged Safely from Referral Letter or Telephone? Sweeney R, Hunter A, Watt M, Patterson V O22 09.30 Stroke mimics presenting at a teleneurology clinic. Kyle K, Patterson V. O23 09.40 Identification of stroke mimics in the emergency department. Tobin O, Hentz J, Demaerschalk, BM O24 09.50 Low prevalence of IgG auto-antibodies to ADAMTS-13 (von Willebrand factor cleaving protease) in ischaemic cerebrovascular disease patients with reduced ADAMTS-13 activity. McCabe DJH, Starke R, Harrison P, Sidhu PS, Brown MM, Machin SJ, Mackie IJ. O25 10.05 Treatment of acute ischaemic stroke with intravenous tPA: the experience in a North Dublin University Hospital. Marnane M, Merwick A, Sheehan O, O’Rourke K, Lynch T, Kelly P. 10.20 – 10.40 Poster Presentation Viewing 10.40 – 11.10 Tea Coffee, Posters and Exhibits Session 4 O26 11.10 Headaches that kill. Lynch K, Mahon C, Brett F. O27 11.20 Retropleural Transthoracic Approach For Complex Thoracic Spinal Pathology. Lee SY, Kelleher MO, McEvoy L, Bolger C. O28 11.30 The Use Of An Expandable Interbody Device (B-TWIN) For Back Dominant Lumbar Disc Disease Collis RA, Kelleher MO, McEvoy L, Fenton E, Bolger C O29 11.40 Intersegmental Decompression Versus Laminectomy In Surgical Management Of Lumbar Spinal Stenosis. Osman T, Kelleher MO, Sattar MT, L. McEvoy, C. Bolger O30 11.55 Outcomes and failures of minimally invasive decompression for focal lumbar spinal stenosis in patients with and without deformity. Kelleher MO, Timlin M, Rampersaud YR. O31 12.10 An Audit of Solitary CNS masses in Patients with known Systemic Malignancy Qassim A, Lim C, Bermingham N, O’Sullivan MGJ, Keohane C. O32 12.25 A Retrospective Review on the Experience and Management of Dysembryoplastic Neuro- epithelial Tumours ( DNET) Aziz M, Johnson D, Farrell MF and O’ Brien D O33 12.40 Cost of disorders of Brain in Ireland Murphy RP, McHugh J, Sobocki PA. 13.00 – 14.00 Lunch Session 5 O34 14.00 Proteomics of Friedreich’s Ataxia. Lakhani A, O’Kane SL, O’Brien J, Iqbal M, Murphy R, Cahill DJ. O35 14.15 Temporal Discrimination Threshold (TDT) and Spatial Discrimination Threshold (SDT) – comparing endophenotypes in Adult-onset Primary Torsion Dystonia (AOPTD). Bradley D, Whelan R, Walsh R, Reilly R, Hutchinson M. O36 14.30 Walsh RJ, Won Kong S, Yao Y, Jallal B, Kiener PA, Pinkus JL, Beggs AH, Amato AA, Greenberg SA. O37 14.45 Aquaporin-4 autoimmunity: A distinctive pediatric inflammatory CNS disorder. McKeon A, Lennon VA, Lotze T, Tenenbaum S, Ness JM, Rensel M, Kuntz NL, Fryer JP, Homburger H, Hunter, J, Weinshenker BG, Krecke K, Lucchinetti CF, Pittock SJ O38 15.00 Genome-wide study of sporadic ALS in a homogenous Irish population Cronin S, Berger S, Ding J, Schymick JC, Washecka N, Hernandez DG, Greenway MJ, Traynor BJ, Bradley DG, Hardiman O. O39 15.15 Eye movement profile in Motor Neurone Disease Donaghy C, Pinnock R, Abrahams S, Cardwell C, Hardiman O, Patterson V, McGivern RC, Gibson JM. 15.30 – 16.00 Tea, Coffee, Posters and Exhibits Session 6 16.00 – 17.00 O’Callaghan Guest Lecture Professor Catriona McLean Director of the Department of Anatomical Pathology, The Alfred Hospital, Victoria, Australia. 'Brainbanking- forming a network'. 17.00 Announcement of Awards Poster Presentations 1. EEG vs CT brain in the confused patient Albertyn C, Doherty CP, Connolly S. 2. Simultaneous Transverse Myelitis and Acute Motor Axonal Neuropathy in an adult. Saidha S, Renganathan, Spillane J, McNamara B, Fanning N, Ryan A 3. Myopathy as the presenting feature of Klinefelter’s Syndrome Kelly SB, Merwick A, Keohane C, McNamara B, Ryan AM 4. Anti-VGCC positive Lambert-Eaton Myasthenic syndrome in association with breast carcinoma Dineen J, Renganathan R, Relihan N, Sweeney B, McNamara B. 5. The Role of Nerve Conduction Studies in Ulnar Nerve Palsy Colliver RJ, Logan A, Shewring, DJ. 6. Correlation Of EEG Findings in Two Confirmed Sporadic CJD Cases In an Inner City Hospital with Published Literature Gaston D, Reid V. 7. An exploration of quality of life issues for people with epilepsy living in the western region of Ireland McGovern T. 8. Levetiracetam Therapy In Human Pregnancy. Updated Experience From The Uk Epilepsy And Pregnancy Register Hunt SJ, Irwin B, Waddell R, Russell A, Smithson WH, Parsons L, Robertson I Morrison PJ, Morrow JI, Craig JJ. 9. Quality of Life in Patients with Epilepsy attending a specialist clinic in Ireland. Bhargava S, Croker MF, Fitzgerald M, Doherty CP 10. Should we be looking more closely at the blood films of epilepsy patients ? Elamin M, Connolly SC, Meaney J, Redmond J. 11. Abnormal gyrification of the cerebral cortex in mesial temporal lobe epilepsy Scanlon C, Ronan L, Doherty C, Delanty N, Fitzsimons M 12. Effects of the anticonvulsant Topiramate on language abilities in epileptic patients: a cross sectional study Buckley A, Fitzgerald M, Hoerold D, Davey G, Doherty CP 13. What do people with epilepsy know about their condition? Evaluation of a subspecialty clinic population Coker, MF, Bargava, S, Fitzgerald M, Doherty CP. 14. A Case of Mistaken Mesial Temporal Identity Neligan A, Holdright DR, Rugg-Gunn FJ, SanderJW 15. The Seizure Service at St. James’ Hospital: an 8 month audit Dardis C, Farid S, Albertyn C, Elamin M, Redmond J, Doherty C. 16. Ictal Bradycardia; Is it a risk for SUDEP? Chaila E, Bhangu J, Delanty N 17. The Spectrum of Associations of Purkinje Cell Antibody Type 1 (PCA-1). McKeon A, Tracy JA, Lennon VA, Parisi JE, Pittock SJ. 18. Central Demyelination in a Patient on Treatment for Psoriasis Spillane J, Moriarty B, Saidha S, Galvin R, Bourke J. 19. Diffusion Tensor Imaging of the Medial Longitudinal Fasciculus (MLF) in Multiple Sclerosis (MS) patients with Internuclear Ophthalmoplegia (INO). Mc Nulty J, Lonergan R, Costelloe L, O’Laoide R, Brennan P, Hutchinson M, Tubridy N. 20. The Predictive Value of B12 Assays in the Neurology Population McKnight K, Duly E, McDonnell M, McConville J. 21. Therapeutic Dilemmas in Aggressive Guillain Barré Syndrome (GBS): A Tale of Two Cases Mawhinney E, Doherty K, McDonnell GV, McConville J. 22. Transient Cardiomyopathy as the Presenting Feature of Acute Disseminated Encephalomyelitis (ADEM). Mawhinney E , McKenna C, Watt M, McDonnell GV 23. Carotid stenosis and stroke; innocent until proven guilty. Iqbal M, Counihan T. 24. Audit of venous thromboembolism prophylaxis in inpatients in the Northern Ireland Regional Neurology Unit Hughes SE, McKenna C. 25. The British Neurological Surveillance Unit study of neurological complications in Behçet’s syndrome. Kidd D. 26. ‘Pulmonary Venous Thrombo-Embolic’ Posterior Circulation Ischaemia And Infarction Kinsella JA, McCarthy AJ, Moore DP, Kiernan T, Mulcahy D, McCabe DJH. 27. Symptomatic ‘SUNA’ associated with severe symptomatic carotid stenosis Kinsella JA, Tobin WO, Costelloe L, Dillane M, McCabe DJH. 28. Cutaneous polyarteritis nodosa and cerebral vasculitis: an unusual association Dineen J, Renganathan R, O’Leary, Sweeney B. 29. Wegener's Granulomatosis with meningeal and cerebral involvement: good outcome following cyclophophasamide treatment Forbes RB, McKillen J, Briggs G, McGoldrick V. 30. Cerebral Venous Thrombosis presenting with headaches and convulsions Soong MM, Carroll A 31. Dialysis Disequilibrium Syndrome – an important consideration in hydrocephalus patients: a case report Shoakazemi A, Flannery T, Woodman A, Mc Laughlin B, Cooke RS 32. An Unexpected Cause of Recurrent Hiccoughs C Kennedy K, Ni Bhuachalla C, Fanning N, O’Sullivan MGJ, Bermingham N, Keohane C, Crosbie O. 33. Comparing MRI findings with clinical outcome in cases of spontaneous intracranial hypotension presenting to the Northern Ireland Neurology Service. Hughes SE, Gray OM, McKinstry S, Flynn P, Forbes RB 34. Gliadel® Therapy In Malignant Gliomas: A Single Centre Study Of The Potential Use Of Gliadel Wafers. Hanif S, Abodunde O, Ali Z, Young S, O’Brien D, Rawluk D. 35. Lhermitte-Duclos Disease: A case report Abdulrahim M, Marks C, Keohane C, Bermingham N 36. Supratentorial Juvenile Pilocytic Astrocytoma in a Young Adult with SilverRussell Syndrome Fenton E, Refai D, See W, Rawluk DJ. 37. Impact of changing teaching methods on undergraduate neurosurgical teaching. Quinn A, Kelleher MO, Bolger C, Hill ADK. 38. Neurosurgery meets W.B. Yeats Lynch K, Brett F, Bolger C, LanganY. 39. The Temporal Discrimination Threshold (TDT) in patients with adult onset primary torsion dystonia (AOPTD) and their relatives – a better endophenotype? Bradley D, Whelan R, Walsh R, Reilly R , Hutchinson M. 40. A Clinical Audit of a Specialist Botulinum Toxin Clinic for Dystonia Ryan M, Sheehan E, Browne G, Molloy F 41. Periodic Paralysis: an under recognised disorder with significant morbidity. Braima O, Ryan A, O’Mahony O. 42. Case Reports Of ASD Closure Causing Migraine In Children Armstrong KR, Farah L, Webb D, O’Mahony O