Lovejoy High School Biology Unit Guide: Genetics (6A-E, 5C: Molecular Genetics) Learning Goals: Describe the contributions of several scientists that worked in the field of DNA Describe the overall structure of DNA Summarize the relationship between DNA and genes Relate the structure of DNA to the function Compare and contrast the structure of DNA and RNA Name the three types of RNA and define their functions Explain the process of transcription, noting its importance and its location Summarize the process of translation and its role in protein synthesis Explain the relationship between genes and proteins. Contrast different types of gene mutations and evaluate their significance Key Terms: DNA, Nucleotide, base pairing, chromatin, histone, replication, dna polymerase, gene, messenger RNA, ribosomal RNA, transfer RNA, transcription, translation, helicase, codon, anticodon, amino acid, mutation, point mutation, frameshift mutation, deletion, insertion, substitution Reading for Understanding: Chapter 12: pages 287-308 Activities: DNA Paper Model, Protein Synthesis Simulation activity, Mutations_practice, Interactive simulations (Holt Book) (6F, 6H: Mendelian Genetics) Learning Goals: Describe how Mendel studied inheritance in peas. Summarize Mendel’s conclusion about inheritance. Describe the principles of probability Predict probability of characteristis using punnett squares for one trait and two traits at a time Contrast mendelian inheritance to non-mendelian inheritance, such as codominance, multiple alleles, and incomplete inheritance. Examine the use of DNA fingerprinting in identification methods Describe and predict genetic disorders identified by chromosomal analysis using karyotypes Predict physical traits in inheritance by using family history in a pedigree. Key Terms: Genetics, trait, hybrid, pure breed, allele, gene, segregation, probability, punnett square, homozygous, heterozygous, phenotype, genotype, incomplete dominance, independent assortment, codominance, multiple alleles, genetic engineering, gel electrophoresis, restriction enzymes, karyotype, sex chromosome, autosome, pedigree Reading for Understanding: Chapter 11: Pages 263-274, Chapter 13: Pages 322-325, Chapter 14: Pages 341-353 Activities: Pedigree_Pratice, Karyotype_Practice, Monohybrid and Dihybrid Problems, Genetic Terminology