Advances in Bio-Separations
Biologics characterisation from cradle to grave
12th – 13th May 2015 MedImmune Cambridge
Complete characterisation of proteins and peptides is essential across a wide range of
industries and applications.
The emergence of protein based bio-pharmaceuticals has resulted in increased reliance on
the chromatographic and spectrometric techniques used to determine the key quantitative
and qualitative attributes of such complex therapeutic entities.
This meeting aims to highlight key advances in the separation and detection techniques
used to analyse peptides and proteins, and we are engaging with speakers whose expertise
lies in the following broad themes

Analytical requirements for characterisation and regulatory filing of proteins / mAbs
/ ADC’s

Chromatographic and mass spectrometric information available at the protein,
peptide and amino acid level

Advances in Ion Exchange chromatography for the detailed characterisation of
charged variants (use of pH v’s buffer gradients etc.)

High performance size exclusion chromatography for analysis of fragments and
aggregates

Coupling Size Exclusion chromatography with MS – the future?

Techniques for biosimilar chacterisation

Reversed phase chromatographic techniques for protein characterisation

Advances in the analysis and characterisation of glycans / glycopeptides

Characterisation and analysis of antibody drug conjugates - advances

Advances in the analysis of important post translational modifications

Affinity chromatography for process monitoring – is speed king?

Preparative bio-chromatography – recent advances, biggest challenges

Modern solutions for the analysis of oligonucleotides

Modern MS techniques in protein characterisation – CID / ETD / ECD and H/D
exchange techniques

HILIC and HIC chromatography in protein analysis – tomorrow or yesterday

High resolution, High Mass accuracy techniques in protein characterisation
Lecturers, Titles, Abstracts & Exhibiting Companies
SPEAKERS (with tentative titles)
Dr Alexander Makarov (ThermoFisher Scientific, Germany)
Bio-Chromatography with Orbitrap detection: past, present and future
Prof Gary Walsh (University of Limerick, Ireland)
Bio-similar characterisation for regulatory approval
Dr Koen Sandra (Research Institute for Chromatography, Belgium)
Strategies for the characterization of biopharmaceuticals: protein, peptide, glycan and
amino acid analyses
Dr Davy Guillarme (University of Geneva, University of Lausanne, Switzerland)
Reversed phase, Size exclusion and Ion Exchange chromatography for biomolecules
characterization
Dr Alistair Kippen ( Medimmune, Cambridge)
Introduction to Biopharm Development & Characterisation of Biologics
Dr Vivian Lindo ( Medimmune, Cambridge)
Mass Spectrometry and the Characterisation of Biologics
Stuart Phillips (Shimadzu, Milton Keynes)
Supporting biologic molecules development using the latest separation and mass spec
techniques
Dr Milena Quaglia (LGC group)
An experimental design protocol for hydrogen deuterium exchange mass
spectrometry experiments and the role of chromatography
Dr. Nadim Akhtar (Astra Zeneca)
Analytical strategies for synthetic oligonucleotides
Dr. Rok Sekirnik (BIA Separations GmbH)
Recent advances in purification and analytics of biomolecules using monolith
chromatography
Dr. Chris Message (Phenomenex)
Monoclonal Antibody Drug Conjugates: Determination of aggregation using GFC
Lucy Fernandes (Waters)
A fast and powerful new solution for released N-glycan monitoring
Dr. John Stenson (Malvern)
Advanced SEC of biopharmaceuticals - More than just Molecular Weight
Dr. Rob Wheller (GSK)
Platform for the bioanalysis of therapeutic proteins utilising automated immunocapture followed by
trapping LC-MS/MS
Alpana Prasad (Protein Simple)
Mastering Charge Heterogeneity Analysis of Biotherapeutics
Scott Fletcher (Crawford Scientific)
The importance of glycosylation profiles in biosimilar and biobetter development –
novel analysis for better control.
SCIEX Presentation Title to be announced
Jaytee biosciences presentation Title to be announced
Dr. Aled Jones (ProZyme & Europa Bioproducts)
N-Glycan Analysis: From High-Throughput Screening to In-Depth Characterization
Dr. Donna Potts (Biopharma Market Specialist EMEA, Agilent Technologies)
Automating Sample Preparation for Improved Biologics Characterisation and Quantitation
Ken Cook (Thermofisher) New Bio-Therapeutics, New Analytical Challenges, New Solutions
Poster presentation from:
Dr. Hiral Panchal (Arihant School of Pharmacy & Bio-Research Institute, India)
Liquid Chromatography For Simultaneous Estimation Of Atorvastatin, Aspirin, Ramipril And
Metformin In Marketed Formulation
EXHIBITING COMPANIES INCLUDE
SHIMADZU
PHENOMENEX
THERMOFISHER SCIENTIFIC
JAYTEE
ARC SCIENCES
CRAWFORD SCIENTIFIC
HICHROM ATG SCIENTIFIC
EUROPA BIOPRODUCTS
ABSCIEX
WATERS
MALVERN
GILSON
AGILENT
PROTEIN SIMPLE
SPONSORSHIP AND EXHIBITION COSTS
GOLD LEVEL SPONSORSHIP £1750


Table top exhibition stand & 20 mins lecture time integrated into the programme
3 free delegate admission places
SILVER LEVEL SPONSORSHIP £1250


Table top exhibition stand & 10 mins lecture time integrated into the programme
2 free delegate admission places
BRONZE LEVEL SPONSORSHIP £750
 Table top exhibition stand and 1 free delegate admission place
DELEGATE ADMISSION PRICES
Member of the Chromatographic Society
or affiliated societies (BMSS, ELRIG or RSC)
£150
Promotional rate for non-members which includes
ChromSoc membership for remainder of 2015
£170
Non members
£180
Bona fide student
£75
NOTE: VAT at 20% is additionally charged on all prices
Please find below the two web links for you to register for the MedImmune Meeting.
For Paying Delegates https://www.eventspro.net/mm/getdemo.ei?id=1070300&s=_DZADUHG0W
For Complimentary Delegates (including Speakers & Committee) https://www.eventspro.net/mm/getdemo.ei?id=1070300&s=_R8TDRHV0W
Evening Corporate Event on 12th May 2015 from 6:45pm
Come Fly with us!
An Evening at the Imperial
War Museum Duxford
The Chromatographic Society Executive
Committee and our meeting speakers
and sponsors invite you to join us for a
very special evening celebrating the
UK’s rich aeronautical heritage.
Includes

Transport from the meeting and afterwards to select local hotels

Drinks Reception

45 minute private tour of the AirSpace Exhibition Hangar, featuring 30 aircraft
including Lancaster, Spitfire and Concorde

Sumptuous 3 Course Dinner *

Private Balcony overlooking the Active Runway at Duxford
This Sponsored dinner is just £50 per person.
Please book your place using the web links above as soon as possible as places are very
limited
*Please advise us if you have special dietary requirements (vegetarian etc)
SPONSORSHIP, LECTURE CONTENT & EXHIBITION STAND ENQUIRIES
Dr. Chris Bevan on chris.anne.bevan@gmail.com &/or
Tony Taylor on tony@crawfordscientific.com
or for general queries and assistance:
Carol McNair
Meeting Makers
Block 4, Unit 4, Kelvin Campus
West of Scotland Science Park
2317 Maryhill Road, Glasgow, G20 0SP
Tel: +44 (0) 141 945 6880
Fax: +44 (0) 141 945 6899
Email: carol@meetingmakers.co.uk WEB: http://www.meetingmakers.co.uk
ORGANISERS
The Chromatographic Society: Founded in 1956, is an
internationally connected organisation and UK registered
charity devoted to the promotion and dissemination of
knowledge on all aspects of chromatography and related
separation techniques.
www.chromsoc.com
Footnotes:
1. The Chromatographic Society’s AGM will be held on May 12th 2015 at this meeting.
2. Chromsoc bursaries are available to attend this symposium:
The Bursary scheme will target young or less experienced chromatographers /separation
scientists currently working in UK based pharmaceutical and biopharmaceutical companies
A maximum of £250 will be awarded per candidate
Details of how to apply are on the Website:
http://www.chromsoc.com/page1132140/industrial-bursaries.aspx