Advances in Bio-Separations Biologics characterisation from cradle to grave 12th – 13th May 2015 MedImmune Cambridge PROGRAMME TIMETABLE AT A GLANCE MAY 12TH 2015 DAY 1 9am to 11am Delegate Registration and Exhibition set up. Tea & coffee available 11:00am Symposium opens: Welcome from MedImmune and The Chromatographic Society 11:15am Dr Alexander Makarov (ThermoFisher Scientific, Germany) Bio-Chromatography with Orbitrap detection: past, present and future 11:50am Prof Gary Walsh (University of Limerick, Ireland) Bio-similar characterisation for regulatory approval 12:25pm LUNCH AND TOUR OF EXHIBITORS STANDS AND POSTERS 2:00pm Dr Koen Sandra (Research Institute for Chromatography, Belgium) Strategies for the characterization of biopharmaceuticals: protein, peptide, glycan and amino acid analyses 2:35pm Dr Davy Guillarme (University of Geneva, University of Lausanne, Switzerland) Reversed phase, Size exclusion and Ion Exchange chromatography for biomolecules characterization 3:10pm Dr Alistair Kippen ( Medimmune, Cambridge) Introduction to Biopharm Development & Characterisation of Biologics 3:45pm Dr Vivian Lindo ( Medimmune, Cambridge) Mass Spectrometry and the Characterisation of Biologics 4:20pm Stuart Phillips (Shimadzu, Milton Keynes) Supporting biologic molecules development using the latest separation and mass spec techniques 4:45pm CHROMATOGRAPHIC SOCIETY ANNUAL GENERAL MEETING 6:15pm Assemble invitees and guests and depart for Duxford Air Park event MAY 13TH 9:15am DAY2 Dr Milena Quaglia (LGC group) An experimental design protocol for hydrogen deuterium exchange mass spectrometry experiments and the role of chromatography 9:50am Dr. Nadim Akhtar (Astra Zeneca) Analytical strategies for synthetic oligonucleotides 10:25am Dr. Rok Sekirnik (BIA Separations GmbH) Recent advances in purification and analytics of biomolecules using monolith chromatography 11:00am Dr. Chris Message (Phenomenex) Monoclonal Antibody Drug Conjugates: Determination of aggregation using GFC 11:20am Coffee break 11:40am Lucy Fernandes (Waters) A fast and powerful new solution for released N-glycan monitoring 12:00 noon Dr. John Stenson (Malvern) Advanced SEC of biopharmaceuticals - More than just Molecular Weight 12:20pm Dr. Rob Wheller (GSK) Platform for the bioanalysis of therapeutic proteins utilising automated immunocapture followed by trapping LC-MS/MS 1:00pm LUNCH AND TOUR OF EXHIBITORS STANDS AND POSTERS 2:15pm Alpana Prasad (Protein Simple) Mastering Charge Heterogeneity Analysis of Biotherapeutics 2:30pm Scott Fletcher (Crawford Scientific) The importance of glycosylation profiles in biosimilar and biobetter development – novel analysis for better control. 2:45pm SCIEX Presentation Title to be announced 3:05pm Jaytee biosciences presentation Title to be announced 3:20pm Dr. Aled Jones (ProZyme & Europa Bioproducts) N-Glycan Analysis: From High-Throughput Screening to In-Depth Characterization 3:30pm Dr. Donna Potts (Biopharma Market Specialist EMEA, Agilent Technologies) Automating Sample Preparation for Improved Biologics Characterisation and Quantitation 3:50pm Ken Cook (Thermofisher) New Bio-Therapeutics, New Analytical Challenges, New Solutions 4:10pm Summary conclusion of the symposium 4:20pm Tea and biscuits and farewell Poster presentation available for viewing throughout symposium from: Dr. Hiral Panchal (Arihant School of Pharmacy & Bio-Research Institute, India) Liquid Chromatography For Simultaneous Estimation Of Atorvastatin, Aspirin, Ramipril And Metformin In Marketed Formulation EXHIBITING COMPANIES INCLUDE SHIMADZU PHENOMENEX THERMOFISHER SCIENTIFIC JAYTEE ARC SCIENCES CRAWFORD SCIENTIFIC HICHROM ATG SCIENTIFIC EUROPA BIOPRODUCTS ABSCIEX WATERS MALVERN GILSON AGILENT PROTEIN SIMPLE