Review: Genetics and Heredity Name: ___________________________________ Objective: Use this sheet in conjunction with your labs, notes, quizzes, homework and extra credit review sheet to study for the exam on Mendelian Genetics (Chapter 11) and Human Genetics (Chapter 14.) The extra credit review sheet is due tomorrow. These are sample questions from the exam for you to practice with! Mendel and Simple Inheritance 1. If an organism is said to be a hybrid, that means they are…? A) Homozygous dominant B) Homozygous recessive C) Heterozygous D) True-breeding 2. A punnett square is used to determine the… A) result of Meiosis I C) result of segregation B) probable outcome of a cross D) actual outcome of a cross 3. When you flip a coin, what is the probability that it will come up tails? A) ½ B) ¼ C) 1/8 D) 1 4. A couple has two children, both of whom are boys. What is the chance that the parents’ next child will be a boy? A) 0% B) 25% C) 50% D) 100% 5. If you have an animal of an unknown genotype, how would you be able to determine its genotype? A) Testcross B) Pedigree C) Karyotype D) All of the above 6. If you were going to perform a testcross for a black hamster, what type of animal would you cross with the animal of unknown genotype? A) Another dominant black hamster C) no cross, look at its siblings B) A recessive white hamster D) none of the above 7. If the offspring from the testcross are half white and half black, you would conclude that the black hamster’s genotype would be? (Given B is black and b for white.) A) BB B) bb C) Bb D) None of the above 8. The passing on of traits from parents to offspring is called ___________. A) Genetics B) Heredity C) Inbreeding D) Gene Splicing 9. Genes located on homologous chromosomes may have alternate forms that control different forms of a trait. These alternate forms of a gene are called ________. A) Alleles B) Centromeres C) Phenotypes D) Gametes 10. Cells containing two alleles for each trait are described as ____________. A) Haploid B) Diploid C) Gametes D) Homozygous 11. An animal that has a genotype of one uppercase letter and one lowercase letter, such as Aa is called ________. A) Homozygous Recessive C) Heterozygous Dominant B) Homozygous Dominant D) Heterozygous Recessive 12. An animal that has a genotype of two upper letters, such as AA is called ________. A) Homozygous Recessive C) Heterozygous Dominant B) Homozygous Dominant D) Heterozygous Recessive 13. An animal that has a genotype of two lowercase letters, such as aa is called ________. A) Homozygous Recessive C) Heterozygous Dominant B) Homozygous Dominant D) Heterozygous Recessive 14. Mendel’s Law of segregation states that during meiosis, the factors that control each trait separate and only ______ from each pair is/are passed to the offspring. A) one factor B) the dominant trait C) two factors D) the recessive trait 15. The law of independent assortment states that the inheritance of alleles for one trait is not affected by the inheritance of alleles for a different trait if the genes for the traits are on ___________. A) separate chromosomes B) the same chromosome C) homologous chromosomes D) homozygous chromosomes 16. A dog’s phenotype can be determined by ___________________. A) looking at the dog’s parents C) mating the dog and looking at the offspring B) examining the dog’s chromosomes D) looking at the dog Complex Inhertiance 17. The type of inheritance shown when a red-flowering plant is crossed with a white-flowering plant and only pinkflowering plants are produced. A) Codominance B) Incomplete Dominance C) Polygenic Inheritance D) Multiple Alleles 18. The type of inheritance that is governed by many genes, like skin color. A) Codominance B) Incomplete Dominance C) Polygenic Inheritance D) Multiple Alleles 19. The type of inheritance where both dominant alleles are expressed/shown in the phenotype, like AB blood. A) Codominance B) Incomplete Dominance C) Polygenic Inheritance D) Multiple Alleles 20. The type of inheritance where there are more than two alleles in a population such as A, B, and O blood. A) Codominance B) Incomplete Dominance C) Polygenic Inheritance D) Multiple Alleles Blood typing 21. What African-American scientist is credited with the process of blood banking and plasma? A) James Watson B) Francis Crick C) Charles Drew D) Rosalind Franklin 22. The red blood cells of a person with type AB blood have a) A antigen only b) B antigens only c) both A and B antigens d) no a or b antigens 23. The red blood cells of a person with type AB blood have a) A antigen only b) B antigens only c) both A and B antigens d) no a or b antigens 24. You know if you have a positive test for a A blood type when the blood smear… A) agglutinates or clumps with Anti-A C) does nothing B) agglutinates or clumps with Anti-B D) Clumps with both anti-A and anti-B 25. Which blood type is the universal donor? 26. Which blood type is the universal recipient? A) A A) A B)B B)B C) AB C) AB D) O D) O Pedigrees and Karyotypes 27. Which parent determines the sex of the offspring and why? A) The mother, because she can give either an X or an Y C) The mother, because she can give either an X or an X B) The father, because he can give either an X or an Y D) The father, because he can give either an X or an X 28. A chart that traces the inheritance of a trait in a family is called…? A) pedigree B) karyotype C) genome D) autosome 29. In a pedigree, males are represented by which symbol? A) Triangles B) Circles C) Squares D) Lines 30. In a pedigree, females are represented by which symbol? A) Triangles B) Circles C) Squares D) Lines 31. In the pedigree above person number II.3 is a(n) a) affected male. c) unaffected male. b) affected female. d) unaffected female. 32. The trait shown in the pedigree above must be A) autosomal dominant C) sex-linked dominant B) autosomal recessive D) sex-linked recessive Human Genetic Disorders 33. During what phase of the cell cycle are chromosomes visible and can be used to create a karyotype? A) G2 phase B) G1 phase C) S phase D) M phase 34. An Extra X chromosome is what disorder? A) Down Syndrome C) Kleinfelter’s Syndrome B) Turner’s Syndrome D) None of these 35. What is the sex of this karyotype? A) male B) female C) Both male & female D) neither male or female 36. What term describes how gametes can receive too many or too few chromosomes? A) nondistinction B) nondisprudence C) nondisjunction D) nondisfiguration 37. What type of chromosomal disorder is when a female receives only one X chromosome? A) Down Syndrome B) Turner’s Syndrome C) Kleinfelter’s Syndrome D) None of these 38. What disease is recessive autosomal and is caused by a lethal accumulation of lipids or fats in the brain? A) Albinism B) PKU C) Cystic Fibrosis D) Tay-Sachs 39. Which of the following diseases is not sex-linked recessive? A) Cystic Fibrosis B) Hemophilia C) Colorblindness D) Duchenne’s Muscular Dystrophy 40. Sickle Cell anemia is a codominant disorder that causes a change in blood cells so they cannot carry…? A) Nitrogen B) Oxygen C) Plasma D) Carbon 41. What type of sex-linked disorder is known for uncontrollable bleeding? A) Sickle Cell anemia B) Cystic Fibrosis C) Achrondroplasia D) Hemophilia 42. Affected males of sex-linked disorders get it from their….? A) Mothers B) Fathers C) Both mother and father D) none of these 43. Affected females of sex-linked disorders get it from their…? A) Mothers B) Fathers C) Both mother and father D) none of these 44. Which of the following would complete this sex-related punnett square? A) XBY B) XbY C) XBXB D) XBXb 45. What would characterize the mother in this sex-related pedigree? A) Homozygous Normal C) Homozygous affected B) Heterozgyous or a Carrier D) Cannot tell from the Punnett square 46. Which of the following best describes the mutation called “B?” A) Deletion B) Duplication C) Inversion D) Insertion E) Translocation 47. Which of the following best describes the mutation called “E?” A) Deletion B) Duplication C) Inversion D) Insertion E) Translocation 48. What type of disorder would be associated with the mutation “C?” A) Fragile X B) Hemophilia C) Acute Myelogenous Leukemia D) Cri du Chat 49. What type of disorder would be associated with the mutation “A?” A) Fragile X B) Hemophilia C) Acute Myelogenous Leukemia D) Cri du Chat 50. How many chromosomes does a normal human have? A) 23 B) 46 C) 92 D) none of these