This form may be completed on line. Tab or move cursor to text field and type in text. *PHYSORDER* ADULT Skin and Soft Tissue Infections (SSTIs) / Cellulitis / Abscess Admission Medication Orders For HIPAA Compliance reasons, this form IS NOT TO BE SAVED with patient information. Selecting the PRINT button will clear all information Page 1 of 2 Form Origination Date: 11/12 Version: 1 Abscess Patient Name MRN PATIENT IDENTIFICATION LABEL Version Date: 11/12 ALLERGIES/DRUG SENSITIVITY: 1. Diagnosis: from the note. 2. Cellulitis 3. Height cm 4. Weight: kg Diagnostics – Check all that apply – for diabetic foot ulcers see additional physician order forms CBC with differential Basic metabolic panel SSTI bacterial cultures (Exudate/aerobic only): Disinfect the venipucture site with chlorhexidine gluconate/alcohol using friction in a back and forth motion for 30 seconds. Allow to air dry for 30 seconds. Abcesss: Exudate aerobic only (from I&D or open abscess) Aspiration (from leading edge) Cellulitis: Aspiration (from leading edge) Blood bacterial cultures x 2 (peripheral blood cultures are preferred) Choose one of three regimens below Adjust doses for renal impairment—see dosing guidelines link for information Contact clinical pharmacist or clinical pharmacy specialist covering service, the antimicrobial stewardship team, or the adult PharmD consult service for assistance if needed Make every effort to document organisms in the wound Regimen I: NON-PURULENT cellulitis (INTACT SKIN) STANDARD REGIMEN (utilize for penicillin allergy — not anaphylaxis) Cefazolin _____ gram(s) IV Q 8 H x 5 days (≤80kg use 1g; >80kg use 2g; renally adjust see chart below) OR PATIENTS WITH A DOCUMENTED ANAPHYLACTIC CEPHALOSPORIN ALLERGY Vancomycin (Loading Dose: 25-30 mg/kg) _____mg IV x 1, then (15 mg/kg) _____mg IV Q _____ H x 5 days (for doses > 2 grams contact PharmD) Regimen II: PURULENT cellulitis and/or non-drainable abscess (NON-INTACT SKIN) STANDARD REGIMEN Vancomycin (Loading Dose: 25-30 mg/kg) _____mg IV x 1, then (15 mg/kg) _____mg IV Q _____ H x 5 days (for doses > 2 grams contact PharmD) Physician Signature SSTIs Pager ID Date Time OTE 900XXX Rev. 11/12 AM/PM This form may be completed on line. Tab or move cursor to text field and type in text. *PHYSORDER* For HIPAA Compliance reasons, this form ADULT Skin and Soft Tissue Infections (SSTIs) / Cellulitis / Abscess Admission Medication Orders Selecting the PRINT button will clear all information from the note. Patient Name MRN PATIENT IDENTIFICATION LABEL Page 2 of 2 Form Origination Date: 11/12 Version: 1 IS NOT TO BE SAVED with patient information. Version Date: 11/12 Management Considerations Refer to Adult Skin and Soft Tissue Infection algorithm for clinical criteria for antibiotic treatment de-escalation and oral antibiotic recommendations. Link Refer to guidelines for prevention, diagnosis and treatment of SSTIs for insights into dosing and antimicrobial selection. Link Clinical Pharmacy Specialists, the Antimicrobial Stewardship Team, or the Adult PharmD Consult Service are available for assistance with drug dosing for patients with impaired renal and hepatic function. Antibiotic dosing based on renal function (see also http://kdpnet.louisville.edu/renalbook/adult/): > 50 ≥ 30 to ≤ 50 ≥ 10 to ≤ 30 ≤ 10 or HD CVVH 1 grams IV Q8H 1 grams IV Q8H 1 grams IV Q12H 1 gram IV Q24H (after HD) 1 grams IV Q12H 15 mg/kg IV Q8-12H 15 mg/kg IV Q12-24H 15 mg/kg IV Q24-48H ≤ 10: dose based on levels HD: 15 mg/kg after each HD 15 mg/kg Q24H CrCl (mL/min) Cefazolin Vancomycin+ + Adjust dosing based on trough levels (goal 10-20 mcg/mL) Physician Signature SSTIs Pager ID Date Time OTE 900XXX Rev. 11/12 AM/PM