UCSF Lab Standard Operating Procedure
Chemical Process, Name or Hazard Class:
Sulfotep
Please fill out the form completely.
Insure all users have access to this SOP.
Refer to instructions for assistance.
Enter text.
Department:
Date SOP was written:
Enter date.
This lab specific SOP has been reviewed and approved by:
Principal Investigator Name:
Enter text.
Principal Investigator Signature
Lab Manager/Supervisor:
Type of SOP:
☐ Process
Enter text.
☒Hazardous Chemical
☐ Hazardous Class
Purpose
Sulfotep (O,O,O′,O′-tetraethyl dithiopyrophosphate) is highly toxic and an environmental hazard. It is used as
an insecticide in greenhouses to insect population.
Physical & Chemical Properties/Definition of Chemical Group
CAS#: 3689-24-5
Class: Acute Toxicant
Molecular Formula: C8H20O5P2S2
Form (physical state): Liquid
Color: Pale yellow or colorless
Boiling point: 136-139 °C
Potential Hazards/Toxicity
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Contact with molten substance may
cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed.
Sulfotep
1
Date: Click here to enter a date.
Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)
Fire may produce irritating, corrosive and/or toxic gases (such carbon oxides and oxides of phosphorous).
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. Contact with
strong oxidizers may cause fires and explosions. May cause irritation, redness, pain and pupillary
constriction. Skin contact with the material may produce severely toxic effects; systemic effects may result
following absorption and these may be fatal. Dermal LD50 for rabbit is 20mg/kg. Severely toxic effects may
result from the accidental ingestion of the material. Effects associated with their use include increased heart
rate, decreased saliva production and other secretions and reduction in bowel movements. Ingestion LD50
for rats is 5mg/kg. Highly toxic by inhalation. Inhalation of dusts, or fume, especially for prolonged periods,
may produce respiratory discomfort and occasionally, distress. Persons with impaired respiratory function,
airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if
excessive concentrations of particulate are inhaled. Highly toxic gases & vapors of unburned material &
phosphoric acid are formed in fires. LC50 for rats is 38 mg/m3.
Engineering Controls
Work with this chemical in a certified ducted fume hood. Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower.
Personal Protective Equipment (PPE)
Respirator Protection
If lab personnel would like to use respirator on a voluntary basis, they must be trained and fit-tested by
EH&S. This is a regulatory requirement. (http://or.ucsf.edu/ehs/8193-DSY/version/default/part/4/data/)
Hand Protection
Handle with nitrile or chloroprene gloves. Gloves must be inspected prior to use. Use proper glove removal
technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and
dry hands.
NOTE: Consult with your preferred glove manufacturer to ensure that the gloves you plan on using are
compatible with Sulfotep.
Refer to glove selection chart from the links below:
http://www.ansellpro.com/download/Ansell_8thEditionChemicalResistanceGuide.pdf
OR
http://www.allsafetyproducts.biz/page/74172
OR
http://www.showabestglove.com/site/default.aspx
OR
http://www.mapaglove.com/
Eye Protection
ANSI approved safety glasses or goggles. Face shield is also recommended.
Skin and Body Protection
Lab coats should be worn. These laboratory coats must be appropriately sized for the individual and be
buttoned to their full length. Laboratory coat sleeves must be of a sufficient length to prevent skin exposure
while wearing gloves. Full length pants and close-toed shoes must be worn at all times by all individuals that
are occupying the laboratory area. The area of skin between the shoe and ankle should not be exposed.
Sulfotep
2
Date: Click here to enter a date.
Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)
Hygiene Measures
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before
reuse.
First Aid Procedures
If inhaled
POISON chemical! If inhaled, get medical aid immediately. Remove victim to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen.
In case of skin contact
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.
In case of eye contact
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Do not use an
ointment. Seek medical attention.
If swallowed
Call the poison control center at 1-800-222-1222. If swallowed, do not induce vomiting unless directed to do
so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Special Handling and Storage Requirements
Handling: Wear protective splash goggles, respirator, gloves and lab attire at all times while handling this
chemical. Use only in a fume hood. This chemical is known to be strong oxidizing agent. It is stable under
recommended storage conditions.
Storage: This chemical should be stored in moisture-proof container in a cool well-ventilated area. Empty
drums should be decontaminated; never re-use containers. Keep in a well-ventilated room. Containers which
are opened must be carefully resealed and kept upright to prevent leakage. Store in secondary containment
with acute toxicant hazard label on the primary container, secondary containment and the storage location.
Spill and Accident Procedure
Chemical Spill Dial 9-911 from campus phone or 415-476-1414 from cell phone or 415-2068522 (SFGH only)
Spill – Assess the extent of danger. Assist contaminated or injured persons. Evacuate the spill area.
Avoid breathing vapors. If possible, confine the spill to a small area using a spill kit or absorbent
material. Keep others from entering contaminated area (e.g., use caution tape, barriers, etc.).
Small (<1 L) – If you have training, you may assist in the clean-up effort. Use appropriate personal
protective equipment and clean-up material for chemical spilled. Double bag spill waste in clear
plastic bags, label and take to the next chemical waste pick-up.
Large (>1 L) – Dial 9-911 from campus phone or 415-476-1414 from cell phone or 415-2068522 (SFGH only) for assistance.
Chemical Spill on Body or Clothes – Remove clothing and rinse body thoroughly in emergency
shower for at least 15 minutes. If discomfort persists, proceed to the Emergency Department. If no
Sulfotep
3
Date: Click here to enter a date.
Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)
further discomfort is experienced, have the SDS ready and contact Poison Control Hotline at 1-800222-1222 for further exposure information. Notify your direct supervisor and EH&S at 415-4761300 during work hours, or 9-911 during non-working hours and weekends.
Chemical Splash Into Eyes – Immediately rinse eyeball and inner surface of eyelid with water for
15 minutes by forcibly holding the eye open. If discomfort persists, proceed to the Emergency
Department. If no further discomfort is experienced, have the SDS ready and contact Poison
Control Hotline at 1-800-222-1222 for further exposure information. Notify your direct
supervisor and EH&S at 415-476-1300 during work hours, or 9-911 during non-working
hours and weekends.
Medical Emergency Dial 9-911 (campus phone) or 476-6911 (cell phone)
Note: All serious injuries must be reported to EH&S at 415-476-1300 within 8 hours.
Non-Life Threatening Emergency– Go to Occupational Health Programs (OHP) Clinic, 415-8857580, 2330 Post Street, Suite 460 Hours of Operation for Appointments: Monday - Friday
7:30 a.m. - 4:00 p.m. (except Holidays).
Note: All serious injuries must be reported to EH&S at 415-476-1300 within 8 hours.
Needle stick/puncture exposure (as applicable to chemical handling procedure) – Wash the
affected area with antiseptic soap and warm water for 15 minutes. For mucous membrane
exposure, flush the affected area for 15 minutes using an eyewash station. Page the needle stick
nurse by dialing 415-353-7842 (STIC).
Decontamination/Waste Disposal Procedure
Clean contaminated surfaces with soap and water and paper towels. Dispose of the paper towels as
hazardous waste.
Safety Data Sheet (SDS) Location
Online SDS can be accessed at http://or.ucsf.edu/ehs/7241-DSY/msds.html
Protocol/Procedure
Quantities covered by this SOP:
______ (g , ml) to _______ (g, ml)
Temperature range covered by this SOP:
__ °C – __ °C
General Overview and Purpose:
Enter the experimental purpose
Procedure:
Sulfotep
4
Date: Click here to enter a date.
Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)
Enter experimental procedure. You can copy procedure from your lab notebook or from literature.
NOTE
Any deviation from this SOP requires approval from the Principal Investigator.
Sulfotep
5
Date: Click here to enter a date.
Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)