REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY SPECIALTY SECTION
ANNUAL REPORT: 2002-2003
I. Officers/Committees:
Officers:
President:
President-elect:
Vice President:
Secretary/Treasurer:
Councilors:
Past-President
II.
2002-2003
Kimberley A. Treinen
Carole A. Kimmel
John M. Rogers
Philip E. Mirkes
Ronald N. Hines
Barbara D. Abbott
Peter Wells
Activities
2002-2003 Meetings:
The Spring 2003 Executive Committee Meeting was held March 11, 2003 in Salt Lake City,
Utah.
The Sprimg 2003 Annual Meeting was held March 12, 2003 in Salt Lake City, Utah. Kimberley
Treinen, as specialty section president, presided.
Meeting Agenda
1) Membership List review
Attendees were encouraged to check their name against the membership list acquired by
Kim Treinen from SOT headquarters. There were many discrepancies noted, and the members
were encouraged to contact SOT to reconcile.
2) Acknowledgement of outgoing and incoming officers
Ron Hines (councilor) and Peter Wells (past-president) outgoing
Dana Shuey (VP elect) and Kim Boekelheide (councilor) incoming
3) Student awards-John Rogers
See below
4) Best paper in Toxicological Sciences-Peter Wells
See below
5) Best paper in Toxicology and Applied Pharmacology-Ron Hines
See below
6) Congratulations to membership that chaired/cochaired 2003 SOT programs
See below for list of sponsored programs. Also, the membership was encouraged to
become involved in generating ideas for future programs. One of the primary responsibilities of
the specialty sections is to put together symposia, etc., for the SOT meeting, and it is mutually
beneficial to SOT and the membership to have cutting edge, interesting programs at the annual
meeting in areas such as reproductive and developmental toxicology. Members were encouraged
to work together in coming up with ideas to lighten the work load in putting together a program.
7) Budget Report
At the end of the fiscal year (June 2002), the specialty section had $5,081.00 in its
account.
8) New Business





A webpage update was presented by Peter Wells. He encouraged the use of the SOT
website for the specialty section. He volunteered to receive mailings to get posted on the
website. Future management was not discussed.
Bylaws update: Peter Wells obtained the specialty section bylaws from SOT and had
them typed. There was a suggestion to revise the bylaws to include a student member as
an officer for the specialty section, but this was not acted upon. It will be discussed at the
2004 specialty section meeting.
Use of teleseminars for specialty section issues/presentations: There was discussion
regarding how the specialty section might use teleseminars to broadcast presentations to
many members of the specialty section simultaneously. This has been successfully used
by the Risk Assessment specialty section.
The membership was reminded about the “Contemporary Concepts in Toxicology”
meetings that specialty section members may want to work with SOT to develop.
Development of ideas for 2004 Program: Carole Kimmel led the discussion, and several
ideas that were later approved by SOT were presented. Submissions for the 2004 program
must be done on line. Carole, as vice president, is the contact person for RDTSS program
submissions.
Specialty Section Sponsored Programs at 2003 SOT meeting:
CE Course
The effects of non-reproductive hormones on the reproductive system and the implications for
toxicology.
Symposia
Temporal specific expression of toxicant-metabolizing enzymes: Implications for life-stagedependent toxicity
Environmental modulation of puberty
Gene-environment interactions in utero: the fetal basis of adult disease (co-sponsored with Mol
Biology)
Innovation in applied toxicology: genomic and proteomic analysis of surrogate tissues for
assessing toxic exposures and disease states (co-sponsored with Mechanisms and Mol Biology)
Genomics and proteomics in reproductive and developmental toxicity
Workshops
Challenges of the developmental neurotoxicity study (co-sponsored with Neurotoxicology and
Regulatory and Safety Evaluation)
Student Awards:
First Place: Julia Kennedy, "Antisense evidence for NF-B-mediated signal transduction in the
mechanism of phenytoin embryopathies,” J.C. Kennedy and P.G. Wells, Faculty of Pharmacy
and Department of Pharmacology, University of Toronto, Ontario, Canada (Abstract #130).
Second Place: Yad Bhuller, "Contrasting developmental roles for ataxia telangiectasia-mutated
(ATM) in modulating the embryonic response to endogenous and xenobiotic-enhanced reactive
oxygen species (ROS) in ATM knockout mice," Y. Bhuller and P.G. Wells, Faculty of
Pharmacy and Department of Pharmacology, University of Toronto, Ontario, Canada (Abstract
#114).
Third Place: Thea Clipson, “Nitric oxide decreases uterine contractility by blocking the closure
of ATP-dependent potassium channels,” T. Clipson, T.J. Miller, M.A. Philbert, and R. LochCaruso, Environmental Health Sciences, University of Michigan, Ann Arbor, MI. (Abstract
#1847).
Best Paper Awards:
Best paper in Toxicological Sciences: Valerie D. Shultz, Suzanne Phillips, Madhabananda Sar,
Paul M. D. Foster, and Kevin W. Gaido. 2001. Altered gene profiles in fetal rat testes after in
utero exposure to di(n-butyl) phthalate. Toxicol. Sci. 64:233-242.
Best paper in Toxicology and Applied Pharmacology:
Xiaozhong Yu, Hisayo Kubota, Ruisheng Wang, Junzo Saegusa, Yasutake Ogawa, Gaku
Ichihara, Yasuhiro Takeuchi, and Naomi Hisanaga. 2001. Involvement of Bcl-2 family genes
and Fas signaling system in primary and secondary male germ cell apoptosis induced by 2bromopropane in rat. Toxicol. Appl Pharmacol. 174:35-48.
Projected Meetings:
Proposed Date
Proposed Location
Spring 2004
Baltimore, MD