University College London JOB DESCRIPTION Job Title: Research Associate / Senior Research Associate – Big Data analysis and clinical translation in cancer imaging Department: Medical Physics and Biomedical Engineering Subsection: Translational Imaging Group Reports to: Prof. Sebastien Ourselin, line managed by Dr. Jorge Cardoso Salary: Grade 7 £33,353 - £40,313 per annum Grade 8 £41,430 – 48,873 per annum (this post is available for 24 months in the first instance) Project Title: Big-data analysis and clinical translation in cancer imaging This is an exciting opportunity for an enthusiastic researcher with skills in scientific computing and large scale data analysis to join an internationally leading university research group. The aim of the project is to have an active role in the development and translation of an image analysis and data mining platform to cancer imaging. Main purpose of the job: The goal of this 2-year EPSRC-CRUK funded translational project is to demonstrate the feasibility, robustness, and clinical value of automated image analysis approaches on clinically relevant and state-of-the-art oncology data. This position specifically aims at developing fully automated image analysis algorithms for highly multimodal imaging data, with an initial application to prostate cancer. The applicant will also be responsible for the translation of our current XNAT platform to cancer imaging, bridging the gap between algorithm developers and end users and thus enhancing the translation of medical image analysis techniques to clinical practice. The post holder will be employed within the Translational Imaging Group with strong interactions between various clinical partners, especially at the UCL Centre for Medical Imaging (CMI) based within University Collge Hospital (UCH) Radiology Department. Person Requirements: The successful candidate will have a PhD in at least one of the following: medical informatics, medical image computing, medical physics, scientific computing or a closely related field. They will be able to demonstrate good mathematical, algorithmic and software development skills. They will also be able to demonstrate strong experience in C/C++ programming and python. Knowledge and experience in high-performance computing platforms, database management and ‘Big-data’ is highly advantageous. Key responsibilities and outcomes: To prototype and develop a novel set of methodological solutions for automated cancer image analysis. To learn the NifTK software architecture with its dependencies, especially the Common ToolKit (CTK) libraries and its command line and scripting interface, and its use for delivering clinically applicable algorithms. To become familiar with the standard radiological digital infrastructure (Picture Archive and Communication System) and its automation. To assist in creating a large cancer-imaging database derived from radiological data. To optimise, translate and/or implement prototyped algorithms for cancer image pre-processing and analysis, with a special focus on prostate cancer, within a clinical environment. To carry out large-scale evaluations, with the aid of the deployed image database, of the prototyped algorithms so as to quantify performance for optimisation. To participate in the full software lifecycle as part of a small team of developers, and to implement software to the required medical standards. To provide comprehensive testing (unit tests, integration tests etc.) for delivered code. To maintain accurate and up-to date technical and user documentation of the delivered software. To attend regular project meetings and training courses for professional and personal development as required. To prepare and present full and regular accounts of progress to colleagues and line managers. To actively contribute to the overall activities of the project team and department as required. To contribute to the induction and direction of other staff and students as requested. To carry out any other duties as are within the scope, spirit and purpose of the job as requested by the line manager or Head of Department. To actively follow UCL policies including Equal Opportunities and Race Equality policies. To maintain an awareness and observation of Fire and Health & Safety Regulations. To maintain an awareness and observation of ethical rules and legislation governing the storage of medical data. To maintain an awareness and observation of confidentiality agreements with collaborators and external organizations. To maintain an awareness and observation of appropriate procedures for the disclosure and protection of inventions and other intellectual property generated as part of the post holder’s activities and those of other team members working within the project. To act with professionalism and efficiency when interacting with colleagues within the project team as well as with external consultants and collaborators. As duties and responsibilities change, the job description will be reviewed and amended in consultation with the post holder. University College London PERSON SPECIFICATION This is a specification of the qualifications, experience, skills, knowledge and abilities that are required to effectively carry out the responsibilities of the post (as outlined in the job description) and forms the basis for selecting a candidate. Job Title: Research Associate / Senior Research Associate – Big Data analysis and clinical translation in cancer imaging Essential Desirable Knowledge, Education, Qualifications and Training 2.1 honours degree (or equivalent) in Computer Science, Engineering, Physics, Mathematics or a related subject. Postgraduate degree (PhD, or equivalent), or equivalent industrial experience, in medical informatics, medical image computing, medical physics, scientific computing or a closely related field including numerical optimisation. *** *** Skills and/or Abilities Ability to work effectively within a collaborative software development environment with people from a variety of backgrounds. *** Excellent written and spoken communication *** skills in English. Strong problem solving abilities. *** Ability to work on own initiative, with minimal supervision. *** Ability to successfully manage tasks to a deadline and to work calmly under pressure. *** Strong problem solving abilities/capable of *** thinking ‘outside of the box’. Strong software/systems engineering skills (including modern techniques for designing and testing software components and software-hardware interfaces). *** High level of proficiency in computer programming using C/C++. *** High level of proficiency in scripting languages, preferably python. *** Proficiency in database management and web service technologies. *** Proficiency in mathematics. *** Proficiency in numerical optimisation. *** Knowledge of version control using software such as SVN, Git. Experience *** Practical experience of algorithm and software development for scientific computing. *** Demonstrable experience of C++ software development within a team, delivering more than just personal research code; eg. opensource projects or product development. *** Experience of supervising PhD students (grade 8 post). *** A good publication record in peer reviewed publications. *** Significant experience in the field (grade 8 post) *** Other requirements Interest in medical image processing ***