Aaron Pyle
CHM 338-102
2/27/13
Portfolio 4: Capillary Zone Electrophoresis
Block Diagram:
Vendors:
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Agilent
Hewlett Peck
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Dionex
Bio-Rad
Fisher Scientific
Research Articles:
1. Sun, H., & Zuo, Y. (2013). Effective Separation and Simultaneous Detection of Ceftriaxone
Sodium and Levofloxacin in Human Urine by Capillary Zone Electrophoresis. Current Analytical
Chemistry, 9(1), 157-162.
-In this experiment ceftriaxone sodium and levofloxacin were effectively separated and identified
from urine. Conditions were optimized until a recovery of 99.15% was reached.
2. Ren, H., Wang, L., Wang, X., Liu, X., & Jiang, S. (2013). Measurement of acid dissociation
constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone
electrophoresis. Journal of pharmaceutical and biomedical analysis, 77, 83-87.
Aaron Pyle
CHM 338-102
2/27/13
-In this experiment the 3-chlorotyrosine (CT) and 3-nitrotyrosine (NT) molecules were determined
to have a wide pH range using the information from the CZE. The diameter of the 3chlorotyrosine (CT) and 3-nitrotyrosine (NT) molecules were also found.
3. Bunz, S. C., & Neusüß, C. (2013). The selective determination of sulfates, sulfonates, and
phosphates in urine by capillary electrophoresis/mass spectrometry. Methods in molecular
biology (Clifton, NJ), 919, 25.
-In this experiment sulfates, sulfonates, and phosphates were selectively determined. A mass
spectrometer was used to quantify/qualify the metabolites.
Common Uses:
-The separation of macromolecules
-Quality control
-Metal ions can be separated by it