St Peter the Apostle High School
BIOLOGY DEPARTMENT
MUTATIONS HOMEWORK
NAME: ________________
TEACHER COMMENT:
PUPIL COMMENT:
PARENT COMMENT:
HOMEWORK 1
1. Which of the following terms describes types of mutation which occur in both genes
and chromosomes?
A Deletion
B Insertion
C Duplication
D Translocation
2. The following is a list of single gene mutations.
1 Nonsense
2 Missense
3 Frameshift
Which of these gene mutations is the result of a single-nucleotide substitution?
A 1, 2 and 3
B 1 and 2 only
C 3 only
D 1 only
3. Which type of gene mutation occurs when a codon for an amino acid is replaced by a
stop codon?
A Nonsense
B Missense
C Frameshift
D Splice-site
4. The diagram below shows two chromosomes, M and N, before and after a
chromosomal mutation.
Which type of mutation has occurred?
A translocation
B duplication
C insertion
D deletion.
5. Individuals with Cri-du-chat syndrome have a shortened chromosome 5. No other
chromosomes are affected. Which type of mutation causes Cri-du-chat syndrome?
A Deletion
B Insertion
C Duplication
D Translocation
6. Which of the following statements refers to gene mutations?
A A change in the chromosome number
B A change in the number of genes on a chromosome caused by duplication
C A change in the structure of a chromosome caused by translocation
D A change in the base sequence of DNA caused by sustitution
7. a)
ii)
b)
8.a)
HOMEWORK 2
Give an account of gene mutation under the following headings:
(i)
Occurrence of mutant alleles and the effect of mutagenic agents (3)
(ii)
Types of gene mutation and how they alter amino acid sequences (7)