NASAPT National Association for Substance Abuse Prevention and Treatment 2300 S. Broad St. Philadelphia Pa. 19145 (215) 285-0832 E-mail: alsummersmd@aol.com.com Etiology-Based Treatment of Mental Illness Introduction Present-day treatment of psychiatric problems involves assembling a cluster of symptoms, making a diagnosis based on this cluster, and designing a treatment strategy to reduce or eliminate symptoms. As advances are made regarding the neurological basis of psychiatric symptoms, treatment must, necessary move in the direction of threating the etiology of the disease process, rather than the symptoms that the underlying factors create. Hypothetical Considerations There are a number of way to depict psychological events. The most familiar being the DSM – 5 in which symptom constellations are formulated into diagnostic categories; from there, the provider refers to textbook accounts as to how these diagnostic categories should be treated. If the psychiatric entity is treatment refractory, the psychiatric literature may provide alternative approaches. For this new approach, symptomology is translated into (1) neurorecptor dysfunction, (2) history of emotional trauma of both the patient and his primary support system, (3) cultural factors, (4) genetic factors, and (5) cognitive impairments, (4) other personality factors, and MRI data which shows damage in specific areas relating to early life trauma. Volterra’s Equations This approach is made possible by virtue of a non-linear calculus, originating from Volterra’s Equations, This calculus describes the result of two conflicting populations, for example perona fish enclosed in a body of water with minnows. The minnows live exclusively on algae; and the perona’s live exclusively on minnows. Volterra’s equations predict the two populations will cycle at regular intervals, but that there will be long quiescent periods in which neither fish scarcely make an appearance. Systems Theory Representation of Dysfunctional Marriage The Failing Marriage is a film that depicts a young married couple, Carolyn and Charley, are enmeshed in argument regarding bringing Nicky, Carolyn’s sister, home to live with the couple for a time. Charlie is adamantly opposed to the plan, and Carolyn, secretly, doesn’t want Nicky to live with them either, but sets Charley up as the bad guy, so that she doesn’t have to feel guilty. During the argument, Carolyn assumes the role of Nicky’s protector, but takes the position of controller with Charley. When Carolyn can’t make any headway as a controller, she switches to martyr. Charlie, on the other hand, starts off as a dictator, but when Carolyn switches to martyr, Charlie then counters in the Bully position. Systems Theory has been successful in describing the dynamic depicted in the film, The Failing Marriage. In order to conform the dynamics of the interaction with Volterra’s equations, a ‘missing link’ had to be accounted for. What was needed, in order to make the mathematics describe the dynamics was an unexpected factor that was responsible that would account for Carolyn making the switch from Controller to Martyr. What made most sense was the introduction of a new entity, discordance. As it turns out, that Carolyn finds herself in a fightvs. flight double bind: if she fights, she is intimidated by Charlie and disrupts her relationship with him. On the other hand, if she moved into a flight response, she feels disloyal to her sister, and humiliated by having to back down to Charlie. This double bind, then, turns out to be an unexpected, although significant factor in the dynamics of the interaction. . Personality Map While Systems Theory can be helpful in describing interpersonal dynamics, the construction of a personality map can afford an opportunity to track interpsychic events that are responsible for symptomology evident in Major Depression, PTSD, Anxiety Disorder, Addiction, and Personality Disorders. Furthermore, as treatment progresses, the personality factors that are remedied can be tracked, and new focuses of treatment can be identified and worked on. 1|Page In order for the personality map to be maximally by useful, it needs to have the linkages between personality factors defined by a rule system consistent with the mathematics (i.e., Volterra’s equations) for which we can find solutions. MRI Data The entire soma, point for point, is mapped on the central gurus, parietal lobe. It is intriguing to think that it may be possible, at some future time, to discover a personality map on the cerebral cortex. There is significant evidence that certain elements of the psyche are mapped on the cortex For example there are areas of damage on the hippocampus in patients who have suffered early – life sexual abuse, and damaged areas on the left temporal lobe in patients who have suffered early-life emotional abuse. This data alone, suggests a neuronal basis for panic attacks eliminating from the hippocampal area, and rage attacks emanating from the left temporal lobe. Future studies, including PET scan data conceivably contribute to a replica of the personality map transposed onto the cerebral cortex. As information to this effect is gleaned, it could be included into Systems Theory and utilized for diagnostic and treatment purposes. PTSD / Receptor Disease Model of Psychiatric Entities Presently, the standard of care is to collect a history and physical, together with a mental status examination, and ascertain a diagnosis via the DSM-5. The treatment recommendation then is sought from an appropriate discussion from an appropriate textbook or journal article. In the future, rather than arrive at a DSM-5 diagnosis based PE, H&P, but an analysis of receptor activity based on similar data, PET & MRI data, endocrineological testing, psychological testing, and multifactor analysis based on computer models. Treatment, then, would be aimed at ameliorating receptor dysfunction, and psychotherapy aimed at dysfunctional thought process, education, and assisting the patient deal with issues relating to PTSD. Thus there may, at some time in the future, be a major shift in thinking; one that focuses on PTSD and receptor dysfunction, but syndromes that result from a dysfunctional system of many elements. Panic Disorder and Intermittent Explosive Disorder, both of which are concomitant illnesses in opiate addiction, leave the patient particularly vulnerable to relapse. With the current philosophy being absence from all substances, medical or otherwise, as the goal of treatment, it is no surprise that the recovery rate for individuals who see misguided absence from all chemicals at about 5%. From the point of view of opiate addiction based on an underlying PTSD and receptor disease dysfunction, one would no more subject the patient to abstinence from a medication so effectuations as Suboxone, than one would subject a type II diabetic to a regimen with a goal of abstinence from insulin. Subliminal Flashbacks. Systems Theory, based on PTSD as the foundation of panic disorder introduces a new element in the etiology of this ailment, the subliminal flashback. The individual, according to this model, has suffered a devastating early life trauma that, for the most part is suppressed. Given an appropriate trigger, a partial flashback takes place, bombarding the individual with an overpowering blast of emotion without any obvious source (since the flashback itself is subliminal). The individual imagines he is suffering a catastrophic heart attack and panics. Once the individual is educated, and finally convinced or the flashback hypothesis, his panic attacks generally abate, an eventually disappear. Intermittent Explosive Disorder. Systems Theory also provides an explanation for rage attacks as the psyche’s attempt to deflect the panic attack by misinterpretation the individual who triggered the flashback as perpetrating a deliberate act of aggression. This justifies retribution on the part of the afflicted individual who then feels justified in launching a vicious counter attack. Character Disorder. Systems Theory results in a depiction of a personality mapping process which has, at its hub, an entity dubbed the core myth. The core myth is a negative belief one holds regarding his self-worth; the bulk of his conscious energy is then spend disguising the negative inference, or overtly denying it. The outcome of a psyche obsessed with reconciling with this erroneous belief is essentially a character disorder. The treatment of character disorders based on the core myth is what has been called a cybernetic analysis in which the individual teases apart the elements that reinforce the core myth and then utilizes a dialectic, cognitive behavioral approach to break away the structures that support the central element, the core myth. Related Discussions Concomitant Benzodiazepines. Particularly regarding the use of benzodiazepines in the treatment of opiate addiction, there is a strong bias against using a habituating drug as a part of the treatment regimen. If the objective becomes harm reduction, however, and the focus on rectifying a dysfunctional system of neuroreceptors, one may see that benzodiazepines can play a pivotal role in a population of persons who are afflicted with rage attacks and panic attacks. Conclusion As more structural findings emerge regarding the association of brain function with behavioral-emotional states, the treatment of mental illness will certainly move in the direction of designing treatment strategies based on etiology, rather than symptomology. As this avenue of thought progresses, it is likely that psychoneurology will eventually evolve into a mathematical science. 2|Page 1 Incorporating PET scan data into Psychoanalytic theory, using Network Theory in Order to Devise a Treatment Strategy for Psychiatric Illness, Alan L. Summers, MD, PhD. American Psychiatric Association Annual Meeting – New York. May 5th, 2004. 2 Harm Reduction Approach and the Concomitant Use of Benzodiazepines in the Treatment of Opiate Addiction. Alan L. Summers, MD, Ph.D. Unpublished. 3 PTSD / Neurorecptor Disease Mode in the Treatment of addictive Disease. Alan L. Summers, MD, Ph.D. Unpublished. 4 Treatment of Panic Disorder as a Variant of Post-traumatic Stress Disorder. Alan L. Summers, MD, Ph.D. Unpublished. 5 Cybernetic Analysis. Alan L. Summers, MD, Ph.D. Unpublished. 6 Step #13 – The Future of Addiction Treatment. Alan L. Summers, MD, Ph.D. Unfinished. 7 of Diagnosis and Treatment of Psychiatric Illness Utilizing Systems Theory. Alan L. Summers, MD, Ph.D. Unpublished, 3|Page