HS 20 - Weir Blood Types Special __________________________ are located on the membrane of some red blood cells. ______________ have the A protein marker ______________ have the B protein marker ______________ have both A and B markers ______________ has no special marker Antigens These protein markers are called __________________. A substance that stimulates the formation of ___________________. Found on _________________________________________________________. Antibodies: Proteins formed within the blood that _______________ with Antigens. Produced in response to a _________________________ to protect the body Found in the ______________________________. Antibodies are specific in function for example: An antibody produced against the flu virus is not effective against HIV Antigens and Antibodies: There are two antibodies called ________________ and _________________. When antibodies are produced they ______________ to the foreign antigen markers The Anti-A will cause any cells having Antigen A to ____________ together, and the Anti-B will cause any cells having Antigen B to clump. HS 20 - Weir This is called _________________________ the clumping of blood cells caused by antigens and antibodies. Type A Blood Type A Blood has A protein markers but it will have ______________ antibodies. (It would be silly to have Anti-A because it would essentially just attack our own blood) Type B Blood Type B Blood has B protein markers but it will have _______________ antibodies. (It would be silly to have Anti-B because it would essentially just attack our own blood) Type AB Blood Since Type AB has both A & B antigens on the surface it does ______________________ antibodies (neither Anti-A or Anti-B) Type O Blood Type O has no protein markers but __________ contain Anti-A and Anti-B antibodies. Blood Type Type A Type B Type AB Type O Antigen on RBC Antibodies Produced HS 20 - Weir Rhesus Factor: During the 1940’s scientists discovered another antigen on the red blood cell – the _____________________________. People who have this antigen are said to be _______. People who do not have this antigen are said to be _______. It is the Rh factor that creates the following blood types: A+, A-, B+, B-, AB+, AB-, O+, O ______ is the most common type of blood. Approximately __________ of Canadians are Rh+ In general, Rh- blood is given to _______ patients Rh+ blood or Rh- blood may be given to Rh+ patients. Blood Transfusions: Since some antigens can trigger a patient's immune system to attack the transfused blood, safe blood transfusions depend on careful __________________________ and ______________________________ We don’t want the recipient’s body to _________ the blood that is being given to them. This would cause the blood to ___________ and not be able to pass through the tiny capillaries. Type AB Blood is considered to be a _________________________________ because type AB has no antibodies it can receive type A, B, AB, or O from a donor However even though AB is a universal recipient, Type AB can only donate to people who have ________________ Blood. Type O Blood is considered to be a ______________________________. Type O contains no antigen therefore a Type O donor can donate to type A, B, AB or O. Even though Type O is a universal donor, a person who has Type O blood can only receive blood from a ____________________ donor. HS 20 - Weir