Design-A-Kid Worksheet Background Gregor Mendel determined that hereditary traits, or genes, are passed from generation to generation with predictable outcomes. In this simulation, you will illustrate the genetic concepts of dominance, segregation, genotype, phenotype, polygenic inheritance, incomplete dominance and multiple alleles when you and your partner “produce” a baby. What will your baby look like if you and your partner (to represent your spouse) both have dominant genes for a particular trait (dominant homozygous)? What if you both have one dominant and one recessive gene (heterozygous)? Objectives After completing this investigation you will be able to: 1. Recognize the relationship between an individual’s genotype and a phenotype. 2. Describe the role of probability in genetics. 3. Differentiate between the terms dominance-recessive; dominance-incomplete dominance; one pair of genes controlling trait-polygenic; alleles-multiple alleles; heterozygoushomozygous. Materials Colored Pens or Pencils Plain Paper Two Coins Procedure 1. To determine the genotype for each trait listed, each partner will flip their coin. HEADS = gamete that contains a dominant gene (unless otherwise indicated) TAILS = gamete contains the recessive gene (unless otherwise indicated) 2. Record the gene contributed by each parent in the provided data table and describe the phenotype of the offspring. 3. When you have determined all the features for a particular structure, ex: with the eyes, draw and color the way the baby will look either as a baby or as a teenager or both. Characteristics Chart Sex of your child: Only father flips as father determines the baby’s sex. If father flips a heads (or a Y chromosome) the baby will be a boy. If the father flips a tails (or a X chromosome, the baby will be a girl. The mother can only give a tails (or X chromosome). Give your baby a name. Face Shape: Round (RR, Rr) Square (rr) Chin Shape: Very Prominent (VV, Vv) Less Prominent (vv) Chin Shape 2: Round (RR, Rr) Square (rr) Hair (incomplete dominance): Curly (CC) Wavy (Cc) Straight (cc) Widow’s Peak: The hair-line comes to a point in the center of the forehead. Widow’s Peak (WW, Ww) No Widow’s Peak (ww) Hair Color: Dark hair is dominant over light To determine the color of your “kid”, assume there are two gene pairs involved. Flip your coins first to determine the genotype of the first pair of genes (AA, Aa, aa). Now flip your coins again to determine the genotype of the second pair of genes (BB, Bb, bb). AABB Black AABb Black AAbb Red AaBB Brown Aabb Regular Blond AaBb Brown aaBB Dark Brown aaBb Regular Brown Aabb Pale Yellow Blond Eyebrows: Not connected (NN, Nn) Connected (nn) Color of Eyebrows: Darker than hair (HH) Distance Apart of Eyes: Close Together (EE) Same as hair (Hh) Average Distance (Ee) Lighter than hair (hh) Far Apart (ee) Eye Size: Large (EE) Medium (Ee) Small (ee) Eye Shape: Almond (wide) (AA, Aa) Eye Slantedness: Horizontal (HH, Hh) Round (narrow) (aa) Upward Slant (hh) Eye Color: Dark eyes is dominant over light Darker eyes are produced in the presence of more active alleles. In this situation, the large letters (A or B) represent alleles which are active in depositing dark pigment. Small letters (a and b) represent alleles which deposit little or no pigment. To determine the color of your “kid’s” eyes, assume there are two gene pairs (alleles involved. One of which codes for depositing pigment in the front of the iris and one of which codes for depositing pigment in the back of the iris. Determine the genotype of the first pair (AA, Aa, aa) and then of the second pair (BB, Bb, bb). AABB AABb AaBB AaBb Intense Brown Intense Brown Brown w/ green flakes Brown AAbb Aabb aaBB aaBb aabb Brown Gray Blue Green Dark Blue Pale Blue Eyelashes: Long (LL, Ll) Short (ll) Mouth: Long (MM) Average (Mm) Short (mm) Lips: Thick (LL, Ll) Thin (ll) Present (DD, Dd) Absent (dd) Dimples: Nose: Big (NN) Medium (Nn) Small (nn) Ear Type: Earlobes Free (GG, Gg) Earlobes Attached (gg) Ear Size: Large (SS) Medium (Ss) Small (ss) Blood Type: This is a bit more difficult. Your results are dependent upon whether you and your partner’s coins have years that are odd, even, or both. If both coins are odd: If both coins are even: If one coin is odd and the other even: Heads = O Heads = O Heads = A Tails = B Tails = A Tails = B Draw next to the name of your kid their blood type. Type O (OO) Type A (AA, AO) Type B (BB, BO) Type AB (AB) Freckles on Cheek: Present (FF, Ff) Absent (ff) Skin Color: To determine the color of skin, assume there are three pairs of genes involved. Flip your coins first to determine the genotype of the first pair of genes (AA, Aa, aa). Then flip your coins again to determine the genotype of the second pair of genes (BB, Bb, bb). Flip for the last time to determine the third pair of genes (CC, Cc, cc). Each capital letter represents an active allele for pigmentation. 6 Capitals 5 Capitals 4 Captials 3 Capitals 2 Capitals 1 Capital No Capitals Very Dark Brown Very Dark Brown Dark Brown Medium Brown Light Brown Light Tan White Design-a-Kid Data Sheet Characteristic Sex Face Shape Chin Shape Chin Shape 2 Cleft Chin Hair Widow’s Peak Hair Color Eyebrows Color of Eyebrows Distance of Eyes Size of Eyes Shape of Eyes Slant of Eyes Color of Eyes Eyelashes Mouth Lips Dimples Nose Ear Type Size of Ears Blood Type Freckles on Cheeks Skin Color Parent 1 Name Parent 2 Name Child’s Name Gene from Father Gene from Mother Genotype Phenotype