Edexcel Advanced Subsidiary GCE in Biology Edexcel As Biology GCE in Biology year 12. Answers to the textbook is found in the folder ‘Answers’ Topic Time spent Course Content Admin Week 1 Expectations of the course Lesson 1 Resources Folder Own notes Complete practical reports Holiday work to complete Reasons for taking the course Discuss designing an experiment Experimental Designing an experiment. Use ‘paper airplane design exercise’ Use ‘experimental senarios’ Use ppt ‘experimental design’ Go through report writing checklist (hand out copy of “report checklist senior”). Show the marking scheme. 1 Report writing folder Show example of a science journal “science journal “ Lesson 2 OR Look at ‘smoking sci report’ Complete the handout ‘variables and data’ OR Complete biozone sheet ‘Variables and data’ pg 18. Just read the information Complete biozone sheet ‘Constructing Tables’ pg 20, saved as ‘constructing tables’ Complete biozone sheet ‘Constructing Graphs’ pg 21. Saved as ‘constructing graphs’ Complete biozone sheet ‘Drawing Line Graphs’ pg 24 to 25. Saved as ‘drawing line graphs’ Complete the handout ‘writing your discussion’ Complete the handout ‘writing your results’ Complete the handout ‘structure of a report’ (use report checklist pg 33 biozone book) Complete biozone sheet ‘Citing and Listing References’ pg 33. Saved as ‘citing and references’ 2 Unit 1: Lifestyle, Transport, Genes and Health 13 wks 40% of the total AS marks Answers to topic 1 ‘unit1 topic1 ans textbk’ AS book folder/ Answers As bk folder Water ppt Water Folder 20% of the total GCE marks (AS) *Unit code 6BI01 Topic 1: Lifestyle, health and risk Demonstrate knowledge and understanding of the practical and investigative skills identified in numbers 4 and 5 in the table of How Science Works on page 13 of this specification. Wk 1 Lesson 3 Lesson 4 Explain the importance of water as a solvent in transport, including its dipole nature. Read through textbook (page 12 to 13), go through the process of taking their own notes. Complete questions in the book (question 1 to 2, page 13) Edexcel As biology Revision guide, Read pg 8 to 9, complete Q 1 to 3. AND Chromatography experiment (practise experimental write up). Compare using wax paper. AND Milk colour and soap (quick class demo) Use ‘properties-of-water-worksheet1’ OR Complete ‘ideal medium transport’ (no resource) 3 Lab prep need. Complete handout ‘water and inorganic ions’ OR Complete biozone sheet ‘Water and Inorganic Ions’ pg 41 to 42. (not question 1 & 5) Complete handout ‘The biochemical Nature of the cell’ answers attached ‘The biochemical Nature cell ans’ OR Complete biozone sheet ‘The Biochemical Nature of the Cell’ pg 39. (read only) Biochemistry folder Demonstrate the floating of a paperclip on water. The above experiment is the first practical report so do not assess it instead just comment on the report. Wk 2 Lesson 1 (really took 2 lessons) Distinguish between monosaccharides, disaccharides and polysaccharides (glycogen and starch – amylose and amylopectin) and relate their structures to their roles in providing and storing energy (β-glucose and cellulose are not required in this topic). ‘biochemicals, Ch. 4,5’ ppt, use it as a brief tool which shows the formation of lipids and carbohydrates. Complete handout ‘organic molecules”, back ground to the importance and how complex the organic molecules are. Answers attached ‘organic molecules answers’ OR Complete ‘organic molecules’, biozone page 40. Complete ‘biochemical structure’ answers ‘biochemical structure answers’ 4 Biochemistry Complete the handout ‘Carbohydrates’, covers the entire outcome. Answers attached ‘carbohydrates answers’ OR Complete biozone sheet ‘Carbohydrate Chemistry’ pg 44. Saved as ‘Carbohydrate Chemistry’. AND Complete biozone sheet ‘Carbohydrates for Energy’ pg 43, Saved as pdf ‘Carbohydrates for Energy’ Week 2 Lesson 2 Describe how monosaccharides join to form disaccharides (sucrose, lactose and maltose) and polysaccharides (glycogen and amylose) through condensation reactions forming glycosidic bonds, and how these can be split through hydrolysis reactions. Read pages 38 to 39, complete Question 1 to 4 page 39. (text book) Biochemistry Read pages 36 to 37, definition of bold words. ‘Biological chemicals’ ppt, Good review for the previous work. Covers units later on. Handout ‘Biochemicals reference material”, just reference notes for the students. Exp “biotechnology to the rescue’ Wk 2 Describe the synthesis of a triglyceride by the formation of ester bonds during condensation 5 Complete ‘carbohydrate structure tutorial’ Read pages 40 to 41, complete Question 1 and 2 page 41. (text book) (quick creep as covered in ppt. Biochemistry reactions between glycerol and three fatty acids and recognise differences between saturated and unsaturated lipids. Wk 2 (took 1 lesson) Explain why many animals have a heart and circulation (mass transport to overcome limitations of diffusion in meeting the requirements of organisms). Edexcel As biology Revision guide, Read pg 14 to 15, complete Q 1 to 2. Complete handout ‘lipids’, outline how important lipids are. Answers use ‘lipids answers’ OR Complete biozone sheet ‘Lipids’ pg 45 to 46 Complete ‘lipid tutorial’ (not the online tut) Review the concept of surface area to volume ratio. Use ppt ‘SAV review’ Surface area to volume ratio folder Complete biozone sheet ‘Surface area and volume’ pg 75 to 76, saved as pdf ‘Surface area and volume’ Read pages 10 to 11, complete Question 1 and 2 page 11. (text book) (end of week 2) Review the lympathetic system using ppt ‘Lympathatic system Review’ Lympathatuc system folder Read pages 14 to 15, complete Question 1 to 2 page 15. (text book). Students make a pie chart to show what percentages that carbon dioxide is carried in the blood (make estimates), students place the blood components as a pie chart. This is a note taking exercise. Make the taking of notes of these pages a class exercise. Review the composition of blood using the ppt ‘Blood Composition’ 6 Circulatory system folder Complete worksheet ‘Blood WS’, answers attached ‘blood ws answers’ (assessment), marking scheme ‘Blood Worksheet MS’ Complete ‘Vertebrates heart WS’ (assessment) (works well with the transport ppt’), marking scheme ‘Vertebrate Heart ms’ OR Biozone pg 50-51 Complete biozone sheet ‘Internal Transport in Animals’ pg 49. Saved as pdf ‘Internal Transport in Animals’ Exp ‘structure of heart dissection simulation’ OR Wk 3 Describe the cardiac cycle (atrial systole, ventricular systole and diastole) and relate the structure and operation of the mammalian heart to its function, including the major blood vessels. Exp ‘structure of heart dissection’ Review ppt ‘circulation Ch. 42’. Some slides basic review while other slides cover this outcome. Complete handout ‘Mammalian Transport worksheet’ OR Complete biozone sheet ‘The Human Cardiovascular System’ pg 50. Saved as ‘The Human Cardiovascular System’ Read pages 24 to 25, complete Question 1 and 2 page 25. (text book) 7 Circulatory system folder Read page 26, definition of bold words and make own notes. Read pages 26 to 27, make list of the bold words and complete questions 1 to 2 page 27. Edexcel As biology Revision guide, Read pg 10 to 11, complete Q 1 to 2. Complete ‘Heart beat WS’ Answers to “control heart activity’ use ‘ Read pages 28 to 29, complete Question 1 to 3 page 29. (text book), Class note taking skill exercise. Creep through with the class. Complete ‘measuring blood pressure’ Complete biozone sheet ‘The Human Heart’ pg 51to 52. Saved as pdf ‘The Human Heart’ Complete biozone sheet ‘The Cardiac Cycle’ pg 53. Saved as pdf ‘The Cardiac Cycle’ OR Complete ‘Heart function ws’, answers attached as ‘Heart function ws answers’ Complete ‘blood pressure summary’ Wk 3 8 Explain how the structures of blood vessels (capillaries, arteries Complete ‘the caridac cycle’ Read pages 18 to 21, definition of bold words, complete Question 1 to 4 page 21. (text book) Circulatory system folder and veins) relate to their functions. (creep through with the class) Complete the handout ‘Circulatory system’. Only page 2. Answers attached ‘Circulatory system answers’ As review questions complete ‘circulation questions’. There are answers attached. ‘circulatoryquestions answers’. Marking scheme ‘Circulatory system Assessment task M S’ (completed in the IGCSE syllabus) Complete ‘Arteries WS’, answers attached ‘Arteries WS answers’ OR Complete biozone sheet ‘Arteries’ pg 54, saved as ‘Arteries’ Complete ‘capillaries and tissue fluid’, answers attached ‘capillaries and tissue ans’ OR Complete biozone sheet ‘capillaries and tissue fluid’ pg 55 Complete ‘Veins WS’, answers attached ‘veins answers’ OR Complete biozone sheet ‘Veins’ pg 57 Complete ‘formation of tissue fluid’, answers attached. (read only, look at the picture) OR 9 Complete biozone sheet ‘formation of tissue fluid’ pg 56 (read only, look at the picture) Exp ‘investigating arteries and veins” Review Assessment Complete ‘AS Biology Review Questions Wk 1 – 2’ (assessment topic test), MS ‘AS Biology Rev Ques Wk 1 - 2 ms’ Review questions Complete Question 1 to 5 page 70 to 71. (text book) Wk 4 Describe how the effect of caffeine on heart rate in Daphnia can be investigated practically, and discuss whether there are ethical issues in the use of invertebrates. Complete ‘Biozone Review Test 39 to 46’, answers ‘Biozone Review Test 39 to 46 ms’ OR Complete ‘Biozone Review Test 39 to 57’, marking scheme attached ‘Biozone Review Test 39 to 57 ms’ Or Complete ‘AS Biozone Review Test pages 39 to 57’, marking scheme attached Tests exams folder/ Biozone tests folder Prelab- discuss the affect of caffine. Read page 27, complete question 1 & 2 page 27. Circulatory system folder First dry lab plan. Make this into a investigation and have the students discuss how this can be modified. OR Use ‘effect of caffine heart rate exp’ The experiment can be modified to see the affect of coffee on small fish. Technical notes ‘effect of caffine heart tech’ OR 10 Complete ‘does caffine affect heart rate’ Read pages 22 to 23, complete Question 1 to 3 page 23. (text book) This can be a note taking exercise. (creep through the chapter) Wk 4 Read pages 16 to 17, complete Questions 1 and 2 Describe the blood clotting process page 17. (text book) (thromboplastin release, conversion of prothrombin to thrombin and fibrinogen to fibrin) and its role in cardiovascular disease (CVD). Use ‘Role of Oxygen and Carbon Dioxide guided Notes’ Board/ summary notes called ‘Describe the blood clotting process notes’ Use the ppt ‘blood clotting process’ {biozone}. Use “Blood clotting handout” Complete worksheet ‘Blood clotting and defence ws’, answers attached ‘Blood clotting defence ans ‘ OR complete ‘blood clotting and cvd’ {biozone} OR Complete biozone sheet ‘Blood Clotting and CVD’ pg 59. Give the students the first page and have them summarise it as a flow chart. This can be made into a flow chart. The flow chart is in their note book. 11 Circulatory system folder Wk 4 Explain the course of events that leads to atherosclerosis (endothelial damage, inflammatory response, plaque formation, raised blood pressure). Read pages 30 to 31, complete Question 1 page 31. (text book) Disease folder (assessment) Q2 page 31 is an assessment task. Use ‘Pg 31 Q2 Marking Scheme’ Use ppt ‘Cardiovascular Disease’, make a flowchart outlining the buildup of plague. Complete ‘cardiovascular disease’ answers attached. {biozone} (question 1 and 2) OR Complete biozone sheet ‘Cardiovascular Disease’’ pg 58 (question 1 and 2) Complete ‘atherosclerosis’, answers attached {biozone} OR Complete biozone sheet ‘Atherosclerosis’ pg 60 Complete ‘atherosclerosis 1_8’ Wk 4 Describe the factors that increase the risk of CVD (genetic, diet, age, gender, high blood pressure, smoking and inactivity). Read pages 32 to 33, complete Question 1 and 2 page 33. (text book) Use ppt ‘Cardiovascular Disease’ Complete ‘cvd risk factors’ with answers attached {biozone} OR Complete biozone sheet ‘CVD Risk Factors’ pg 61to 62. 12 Disease folder Complete ‘cholesterol as a risk factor’, answers attached {biozone} OR Complete biozone sheet ‘cholesterol as a risk factor’ pg 63 Complete ‘sudden deaths in athletes’ Edexcel As biology Revision guide, Read pg 12 to 13, complete Q 1 to 2. Edexcel As biology Revision guide, Read pg 16 to 17, complete Q 1 to 2. Wk 5 Describe the benefits and risks of treatments for CVD (antihypertensives, plant statins, anticoagulants and platelet inhibitory drugs). Read pages 64 to 67, complete Question 1 to 6 page 67. (text book). Taking of own notes is an inclass skills exercise. Disease folder Use ppt ‘Drugs Treating Heart Disease’ View ‘Love boat,’ 8 min 24 sec AD showing statins Complete ‘treating cvd with drugs’, answers attached {biozone} OR Complete biozone sheet ‘treating cvd with drugs’’ pg 64 Complete ‘mark and peter story’ Wk 5 13 Analyse and interpret data on the possible significance for health of Complete ‘new treatments cardiovascular disease’ Board notes and ppt on cholesterol, its structure and different types. Read pages 60 to 61, Assess the Disease folder blood cholesterol levels and levels of high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). Describe the evidence for a causal relationship between blood cholesterol levels (total cholesterol and LDL cholesterol) and CVD. Wk 5 Discuss how people use scientific knowledge about the effects of diet (including obesity indicators), exercise and smoking to reduce their risk of coronary heart disease. accuracy of the information on these pages. Make notes on the pages, student note skill exercise. (text book) (creep through this section) Use ‘cholesterol and cvd’ Use ‘excel CHD calculator’ and ‘excel coronary heart disease’ (exercise in using excel) Discuss in the class why people continue to smoke and brain storm how the government can combat this. Disease folder Assess in class how accurate a survey of the 6500 finish people in relation to fresh fruit and cancer. OR Ppt ‘Data analysis’ Data analysis folder Read pages 68 to 69, complete Question 1 to 3 page 69. (text book) Complete ‘Evaluating the risk’, answers attached {biozone} OR Complete biozone sheet ‘Evaluating the risk’ pg 65 complete ‘analysis of cardiovascular disease data’ saved as word or pdf complete ‘functional food and chd’ 14 Disease folder Review Wk 6 Describe how to investigate the vitamin C content of food and drink. complete ‘healthy heart quiz’ (Assessment) use “AS Circulatory and Nutrition Topic Test” Discuss Mawson and Mertz, the difference between macro and micro nutrients. View “Mawson article’ and use ‘Mawson and Mertz Expedition’ ppt Tests exam folder Nutrition folder OR Use ‘Case of the vit A Murder’, read in class. Complete experiment. ‘vit C content juice exp’ , teacher notes available. technician notes ‘vit C juice exp tech’ OR Write up found in ‘vitamin C test’ Complete ‘is high C all it claims to be’ Review Wk 6 Analyse data on energy budgets and diet so as to be able to discuss the consequences of energy imbalance, including weight loss, weight gain, and development of obesity. (assessment optional) Use ‘Vitamin C U3 practice Question”, examiners report attached (20 minute test) Tests folder Read pages 34 to 35, complete Question 1 and 2 page 35. (text book) (creep) Nutrition folder Read pages 48 to 49, complete Question 1 to 4 page 49. (text book) Read pages 50 to 51, complete Question 1 and 2 15 page 51. (text book) Use ppt ‘nutrition deficiency’ Complete ‘your energy budget’ Complete biozone sheets “maintaining a healthy Weight” and “A balanced diet” OR Complete biozone sheet ‘A Balanced Diet’ pg 67 to 68. Complete ‘are you getting enough antioxidants’ Complete ‘maintaining a healthy weight’, answers attached {biozone} OR Complete biozone sheet ‘maintaining a healthy weight’ pg 66 Wk 6 Analyse and interpret quantitative data on illness and mortality rates to determine health risks (including distinguishing between correlation and causation and recognising conflicting evidence). Read pages 52 to 53, complete Question 1 to 6 page 53. (text book) Read pages 62 to 63, complete Question 1 and 2 page 63. (text book) (assessment) Complete ‘links lifestyle disease’, answers attached ‘links lifestyle disease ans’ Marking scheme ‘links lifestyle disease ms’ Use ‘Saudi data interpretation’ article to show about data interpretation. 16 Data analysis folder Use ‘Al Arabiya news’ another article a year later quoting scientific prove from the leader of arab consultant. OR use ‘Reuters news saudi driving’ AND Use ‘The Guardian saudi driving’ which critises the research. Use ‘smoking and death’ and ‘smoking and cancer’ so see is there is a correlation in the data. Complete ‘making decisions’ Wk 7 Evaluate design of studies used to determine health risk factors (including sample selection and sample size used to collect data that is both valid and reliable). Complete ‘links bw lifestyle heart act’ teacher notes attached Read pages 54 to 55, complete Question 1 to 3 page 55. (text book) (creep through) Read pages 56 to 57, complete Question 1 and 2 page 57. (text book) Creep through, mention Longitudinal studies, Metadata studies, Reliable, precision, biased, evaluate, valid. Use ‘Making a case study’ Use ‘Data error margins’ ppt to see error margins Discuss ‘Annual Deaths Attributable to Cigarette Smoking’ OR Discuss ‘fig 2 smokeless tobacco’ 17 Data analysis folder Discuss ‘fig 1 smoking trends’ to see if data shows significance differences. Discuss ‘smoking_ethnicity’ excel Discuss if data is significant or not, use ‘smoking_socioeconomic’ Edexcel As biology Revision guide, Read pg 18 to 19, complete Q 1 to 2. Complete ‘identify health risks’ Wk 7 Explain why people’s perceptions of risks are often different from the actual risks (including underestimating and overestimating the risks due to diet and other lifestyle factors in the development of heart disease). Read pages 58 to 61, complete Question 1 to 3 page 61. (text book). Summarise the information in a table. (creep through/ own notes) Data analysis folder Edexcel As biology Revision guide, Read pg 20 to 21, complete Q 1 to 2. Complete ‘estimating risk’ Review {Biozone} Key terms: Memory Card Game. Page 69 to 70. Edexcel As biology Revision guide, complete Q 1 to 3., pg 24 to 25 18 Complete ‘Review essays for health and lifestyle’. Answers ‘Marking scheme for Health and lifestyle review questions’. Health folder Use ‘check your notes topic 1’ Review Questions folder Complete ‘examzone unit 1 topic 1’ answers attached (assessment exam) Topic 2: Genes and health Demonstrate knowledge and understanding of the practical and Use Biozone test ‘Biozone test AS 50 to 68’, answers ‘Biozone test AS 50 to 68 ms’ Answers to textbook questions ‘unit1 topic2 ans textbk’ investigative skills identified in numbers 4 and 5 in the table of How Science Works on page 13 of this specification. Wk 1 (wk 8) Explain how models such as the fluid mosaic model of cell membranes are interpretations of data used to develop scientific explanations of the structure and properties of cell membranes. ‘Read pages 100 to 103, complete Question 1 to 3 page 103. (text book). Definition of the bold words. Use ppt ‘cell membrane’ Complete biozone sheet ‘How do we know? Membrane structure’ pg 72, (scanned copy with answers ‘How we knw Membane struture’) Complete biozone sheet ‘The structure of membranes’ pg 73- 74(scanned copy with answers ‘The structure of membranes’) (not Q8) OR Complete ‘structure of membranes handout 97 ver’ Edexcel As biology Revision guide, Read pg 30 to 31, complete Q 1 to 2. (think question 1) Complete ‘cell membrane structure function’ 19 Tests exams folder AS book folder/ Answers As bk folder Membrane structure folder (assessment). Answers scheme ‘Membrane structure function ms’ Use ‘fluid mosaic model resources 1’ and ‘fluid mosaic model resources 2’ Wk 1 (wk 8) Explain what is meant by osmosis in terms of the movement of free water molecules through a partially permeable membrane (consideration of water potential is not required). Extension, use ‘Membranes and organelles class discussion notes’ Read pages 106 to 107, complete Question 1 to 2 page 107. (text book). Definition of the bold words Use ppt ‘specialised transport’ Complete biozone sheet ‘osmosis in cells’ pg 79-80. Saved as pdf ‘osmosis in cells’ Use ‘Osmosis ppt’ ppt Use ppt ‘hypo hyper isotonic ppt’ Use demonstration of two eggs that has been deshelled in vinegar and placed in distilled water and another in sugary water (use the same egg to some it continually change size). Inclass describe and explain. OR Demonstrate the changes in the size of the eggs without a shell in two different solutions. Use ‘Marking Scheme for Hypotonic cell experiment’ Experiment of the changing of mass of potato cores placed in different concentrations of sugar solution. (assessment practical report) 20 Membrane structure Diffusion and osmosis Wk 1 (wk 8) Explain what is meant by passive transport (diffusion, facilitated diffusion), active transport (including the role of ATP), endocytosis and exocytosis and describe the involvement of carrier and channel proteins in membrane transport. Inclass demo, compare the size of blood and onion cells in fresh and salt water. Read pages 104 to 105, complete Question 1 to 3 page 105. (text book). Definition of the bold words Read pages 108 to 109, complete Question 1 to 2 page 109. (text book). Definition of the bold words (creep through the evidence section) Membrane structure folder Use ppt ‘transport across membrane’ Complete biozone sheet ‘active and passive transport’ pg 77. Saved as pdf ‘active passive transp’ Complete biozone sheet ‘ diffusion’ pg 78. Saved as pdf ‘diffusion’ diffusion and Osmosis folder Complete biozone sheet ‘exocytosis and endocytosis’ pg 81. Saved as pdf ‘Exocytosis endocytosis’ Membrane structure folder Complete biozone sheet ‘ion pumps’ pg 82. Saved as pdf ‘Ion pumps’ Edexcel As biology Revision guide, Read pg 32 to 33, complete Q 1 to 2. Think task Q1 Complete ‘Osmosis and Diffusion’ Exp ‘method transport within between cells’ 21 diffusion and Osmosis folder Wk 2 Wk 2 (wk 9) Describe how membrane structure can be investigated practically, eg by the effect of alcohol concentration or temperature on membrane permeability. Describe the properties of gas exchange surfaces in living organisms (large surface area to volume ratio, thickness of surface, difference in concentration) and explain how the structure of the mammalian lung is adapted for rapid gaseous exchange. Use ppt ‘Cell Transport summary’ Complete ‘temperature on membranes’, technician notes available. Membrane structure folder OR Use ‘why does colour leak out of cooked beetroot’ Read pages 110 to 111, complete Question 1 to 2page 110. (text book). Definition of the bold words Surface area to volume ratio folder Use the ppt ‘surface area to volume ratio’ Complete ‘Surface Area to Volume Ratio’. The same work sheet is in the biozone book page 75 to 76. Read pages 112 to 113, complete Question 1 to 3 page 113. (text book). Definition of the bold words Complete biozone sheet ‘ the human gas exchange system’ pg 83 to 84. Saved as pdf ‘human gas exch’ Complete ‘alveoli and lung surface area’ Complete ‘structure of alveoli; Read pages 114 to 115, complete Question 1 to 2 page 115. (text book). Definition of the bold words. Complete own notes/ or creep. Exp ‘demonstrating mass flow’ 22 diffusion and osmosis folder Wk 2 (wk 9) Describe the basic structure of an amino acid (structures of specific amino acids are not required) and the formation of polypeptides and proteins (as amino acid monomers linked by peptide bonds in condensation reactions) and explain the significance of a protein’s primary structure in determining its three-dimensional structure and properties (globular and fibrous proteins and types of bonds involved in three-dimensional structure). Exp ‘structure of alveoli’ Read pages 42 to 43, own notes and definition of bold words Read pages 44 to 45, complete Question 1 to 4 page 45. (text book) Use ppt ‘amino acids and protein’ Use ppt ‘Protein Structure’ (many of the slides are a review) Complete ‘proteins’ Complete ‘Practise AP exam question protien structure’ (answers found ‘Practise AP exam question protien structure answers’) Use ppt ‘membrane proteins’ to show example of different proteins. Complete model of protein (assessment). Use ‘Protein Structure Assignment’ Complete biozone sheet ‘amino acids’ pg 87 – 88. Saved as pdf ‘amino acids’ Complete biozone sheet ‘proteins’ pg 89-90. Saved as pdf ‘Proteins structure’ Read pages 46 to 47, complete Question 1 and 2 page 47. (text book) (creep) 23 Proteins folder Edexcel As biology Revision guide, Read pg 26 to 27, complete Q 1 to 2. Wk 3 (Wk 10) Explain the mechanism of action and specificity of enzymes in terms of their three-dimensional structure and explain that enzymes are biological catalysts that reduce activation energy, catalysing a wide range of intracellular and extracellular reactions. Read pages 84 to 85, complete Question 1 to 3 page 85. (text book) Enzymes folder Use ‘enzyme evidence’ Read pages 86 to 89, complete Question 1 to 2 page 89. (text book). Get a definition of the bold words. Define the difference between intra and extracellular enzymes. Class discussion how enzymes are used in medicine “discuss HSW enzymes in medicine” Complete biozone sheet ‘enzymes’ pg 91 -92. Edexcel As biology Revision guide, Read pg 28 to 29, complete Q 1 to 2. (think question 1) Wk 3 (wk 10) 24 Describe how enzyme concentrations can affect the rates of reactions and how this can be investigated practically by measuring the initial rate of reaction. Complete ‘gas transport in humans’ (online), shows how changing enzyme shapes are useful and reviews transport system. Answers attached ‘gas transport in humans answers’ Circulation folder Use ‘enzymes’ ppt Enzymes folder Use ‘enzymes function’ ppt Complete biozone sheet ‘enzyme reaction rates’ pg 93. Saved as ‘enzyme reaction rates’ Experiment on the breakdown of protein using different concentrations and conditions. Students write up experiment and have the class design the experiment focus on variables. Only change the concentration. Use starch and amylase. (abbreviated Report) Use ‘buriet test’ for the testing in this experiment OR use ‘buriet test instructions’ OR Use ‘Investigating the effect of enzyme concentration on the breaking down of protein in milk’ OR Complete ‘enzyme conc and react exp’, teacher and technician notes available. Wk 3 (wk 10) Wk 4 (wk 11) 25 REVIEW Describe the basic structure of mononucleotides (as a deoxyribose or ribose linked to a phosphate and a base, ie thymine, uracil, cytosine, adenine or guanine) and the structures of DNA and RNA (as polynucleotides composed of mononucleotides linked through condensation reactions) and describe how complementary base pairing and the hydrogen bonding between two complementary strands are involved in the formation of the Experiment: ‘enzyme concentration and activity’ Complete biozone sheet ‘key terms: crossword’ pg 85 Read pages 74 to 75, complete Question 1 to 2 page 75. (text book) Use ‘dna rna structure’ ppt Complete ‘dna model’ Complete biozone sheet ‘nucleic acids’ pg 94 – 95 Complete biozone sheet ‘creating a DNA model’ pg 99-101. (optional) DNA RNA structure DNA double helix. Edexcel As biology Revision guide, Read pg 34 to 35, complete Q 1 to 2. Think task Q1 Read pages 76 to 77, complete Question 1 to 2 page 77. (text book). Student are to summarise in a table. The table format is “who”/”evidence”/”Inference made”. Exp ‘extraction of dna’ Ext ‘who was rosalind franklin’ Wk 4 (wk 11) Ext ‘working out the dna code’ Use ‘DNA Replication’ ppt Describe DNA replication (including the role of DNA polymerase), and Read pages 78 to 79, complete Question 1 to 2 page explain how Meselson and Stahl’s classic experiment provided new data that supported the accepted theory of replication of DNA and refuted competing theories. DNA RNA structure 79. (text book) Complete biozone sheet ‘Meselson and Stahl’s experiment’ pg 96 Complete biozone sheet ‘DNA replication’ pg 97 -98 Complete biozone sheet ‘review of DNA replication’ pg 103 (optional) Complete ‘meselson and stahl exp dna replication’ Edexcel As biology Revision guide, Read pg 36 to 37, complete Q 1 to 2. Think task Q1 & 2 Wk 5 (wk 12) 26 Explain the nature of the genetic code (triplet code only; non-overlapping and degenerate not required at AS). Use ‘gene expression eukaryote’ Use ‘Expression of genes’ Gene expression folder Use ‘genetic code’ ppt Wk 5 (wk 12) Wk 5 (wk 12) Describe a gene as being a sequence of bases on a DNA molecule coding for a sequence of amino acids in a polypeptide chain. Outline the process of protein synthesis, including the role of transcription, translation, messenger RNA, transfer RNA and the template (antisense) DNA strand (details of the mechanism of protein synthesis on ribosomes are not required at AS). Complete biozone sheet ‘the genetic code’ pg 104 Read pages 80 to 81, complete Question 1 page 81. (text book) Protein synthesis folder Show ‘Amino Acid protein table’ show the universal codon table Review using ‘DNA Transcription and Protein Assembly’ (was shown previous grade) Protein synthesis folder Show ‘DNA Transcription‘, ‘DNA Transcription and Protein Assembly’, “Protein Synthseis’. Protein translation and transcription simulation. Use ‘Protein Synthesis Report guidelines’ (to be used with the above simulation) Complete biozone sheet ‘the simplest case: genes to proteins’ pg 105 Complete ‘nucleic acids protein synthesis’ Review Wk 6 (wk 13) 27 Explain how errors in DNA replication can give rise to mutations and explain how cystic fibrosis results from one of a number of possible gene mutations. Use ‘Practise transcription question’ for students to practise their answering of questions Read pages 116 to 119, complete Question 1 to 4 page 119. (text book). Use ppt ‘mutations’ OR Use ‘genetic diseases’ ppt Protein synthesis folder Mutation folder Read pages 82 to 83, complete Question 1 to 2 page 83. (text book) Use ppt ‘Mutation causes’ Complete biozone sheet ‘causes of mutations’ pg 106 Complete biozone sheet ‘inherited metabolic disorders’ pg 108 Complete ‘gene mutation story’ Complete ‘after the funeral’ Wk 6 (wk 13) Explain the terms gene, allele, genotype, phenotype, recessive, dominant, homozygote and heterozygote, and explain monohybrid inheritance, including the interpretation of genetic pedigree diagrams, in the context of traits such as cystic fibrosis, albinism, thalassaemia, garden pea height and seed morphology. Complete ‘CFTR protien membrane transport lung’ Read pages 90 to 93, complete Question 1 to 4 page 93. (text book). Get a definition of bold words. Complete biozone sheet ‘alleles’ pg 111 Complete biozone sheet ‘phenotype and genotype’ pg 112. Read pages 94 to 95, complete Question 1 to 3 page 95. (text book). Make sure that the students write out the laws. Complete ‘Calculating genetic crosses’. Answers attached ‘calculate genetic cros ans’ Complete ‘selection exercises’. Answers ‘selection 28 Proteins folder Genetic prediction folder exercises ans’ Complete biozone sheet ‘Mendel’s pea plant experiments’ pg 113 Read pages 96 to 99, complete Question 1 to 6 page 99. (text book). Definition of bold words. (creep through) Complete biozone sheet ‘monohybrid cross’ pg 114. Complete biozone sheet ‘pedigree analysis’ pg 115116 Complete ‘inheritance problems’ Activity: ‘reebops’ Edexcel As biology Revision guide, Read pg 40 to 41, complete Q 1 to 2. Think task Q1 Use ‘Pedigree_XLinked tree’ pdf OR Use ‘PedigreeAnalysisInGenetics’ Wk 6 (wk 13) 29 Explain how the expression of a gene mutation in people with cystic fibrosis impairs the functioning of the gaseous exchange, digestive and reproductive Read pages 120to 121, complete Question 1 to 3 page 121. (text book). Mind map of drug therapies. Use ppt ‘cystic fibrosis’ Disease folder systems. Complete biozone sheet ‘ the effects of mutations’ pg 107 (read only) Complete biozone sheet ‘cystic fibrosis mutation’ pg 109 – 110 Edexcel As biology Revision guide, Read pg 38 to 39, complete Q 1 to 2. Think task Q1 & 2 Activity: ‘passing it on’ Wk 7 (wk 14) Describe the principles of gene therapy and distinguish between somatic and germ line therapy. Complete ‘personal cf stories’ Read pages 122 to 124, complete Question 1 to 4 page 124. (text book). Give 5-10 minutes to make own notes. Read ‘HSW Mouse models of CF”, pg 124. Make a table outlining the pros and cons of testing on the mouse OR Evaluate and judge using a mouse to model the treatment of CF. Read ‘HSW The ethics of gene therapy” and compare and contrast germ line vs somatic cell therapy. Present in a table, include the ethics behind both. Use ppt ‘Gene Therapy’ Use handout ‘Genetic engineering’ Complete ‘gene therapy story’ Complete biozone sheet ‘gene therapy’ pg 117 30 gene technology folder Complete biozone sheet ‘vectors for gene therapy’ pg 118 Complete biozone sheet ‘gene delivery systems’ pg 119 – 120 Edexcel As biology Revision guide, Read pg 42 to 43, complete Q 1 to 2. Think task Q1 & 2 Wk 7 (wk 14) Explain the uses of genetic screening: identification of carriers, preimplantation genetic diagnosis and prenatal testing (amniocentesis and chorionic villus sampling) and discuss the implications of prenatal genetic screening. Read pages 126 to 129, complete Question 1 to 4 page 129. (text book). Definition of the bold words Use the ppt ‘Genetic Screening’ gene technology folder Complete activity ‘Human chromosome analysis’, answers attached. Complete ‘genetic screening’ Discuss the role of a pedigree tree tracking down haemophilia. Complete ‘predigree tree haemophilia’ (saved in word and pdf) Genetic prediction folder Complete ‘genetic worksheet’, answers attached as ‘genetic worksheet ans’ Complete biozone sheet ‘genetic testing’ pg 121 – 122. Review (genetic prediction) Complete biozone sheet ‘postnatal testing’ pg 123 Use ‘Classical genetics worksheet’ quiz review test OR Use ‘genetics wkst’ 31 Genetic prediction folder Wk 7 (wk 14) Identify and discuss the social and ethical issues related to genetic screening from a range of ethical viewpoints. Review Use ‘Ethics of gene tech’ ppt Read ‘Bloomberg Gene patent article’ gene technology folder OR Read discuss ‘human gene patent court case’ Complete biozone sheet ‘key terms: mix and match’ pg 124. Tests exams folder Edexcel As biology Revision guide, Read pg 45; Complete questions on page 46 to 51 complete Questions page 130 to 131. Compete ‘Examzone unit 1 topic 2’ answers attached Complete ‘check your notes topic 2’ Unit 1 Review/ assessment 32 Complete ‘Biology GCE unit 1 jan 2011’ OR Complete ‘bio GCE U1 jan 2011’, answers ‘bio GCE U1 jan 2011 ms’ Review Questions folder Tests exam folder/ jan 2011 folder Complete ‘Bio GCE U1 Jun 09’, answers attached ‘Bio GCE U2 U1 Jun 09 ms’ Tests exam folder/ jun 2009 folder Complete ‘Bio GCE U1 Jan 09’, answers attached ‘Bio GCE U1 Jan 09 ms’ Tests exam folder/ jan 2009 folder Wk 15 Unit 2: Development, Plants and the Environment Complete ‘Bio GCE U1 Jun 2010’, answers attached ‘Bio GCE U1 Jun 2010 ms’ Tests exam folder/ jun 2010 folder Complete ‘Bio GCE U1 Jan 2010’, answers attached ‘Bio GCE U1 Jan 2010 ms’ Tests exam folder/ jan 2010 folder Complete ‘Bio GCE U1 jun2011’, answers attached ‘Bio GCE U1 Jun 2011 ms’ Tests exam folder/ jun 2011 folder Answers to textbook “unit2 topic3 ans textbk’ AS book folder/ Answers As bk folder 40% of the total AS marks 20% of the total GCE marks *Unit code 6BI02 AS Topic 3: The voice of the genome Demonstrate knowledge and understanding of the practical and investigative skills identified in numbers 4 and 5 in the table of How Science Works on page 13 of this specification. Wk 1 33 Distinguish between eukaryotic Read pages 132 to 135, complete Question 1 to 2 page 135. (text book). Definition of bold words. and prokaryotic cells in terms of their structure and ultrastructure. Use ‘Microscopes ppt’ ppt Complete ‘Microscope Scale’ Microscopes folder Complete ‘the light electron microscope’ (needs ‘scale of sizes handout’) Complete ‘Assessment Homework 2’ (assessment). Complete biozone sheet ‘Electron Microscopes’ pg 135 - 136 Complete biozone sheet ‘cell sizes’ pg 142 Handout ‘scale of sizes’ Read/ use ‘cell_structure_and_function’ (covers many pts) (reserve) (show slide 1 to 32) Stop at comparing the Eukaryotic and prokaryotic cells. Cell sizes folder Complete ‘size of cells and organelles’, answers ‘size cells organelles ans’ Show ‘procaryotes old’ to show how the ideas have changed (this ppt was made in 2003) Use ppt ‘procaryotes’ to outline the prokaryotes. Handout ‘eucaryotic vs procaryotic’ 34 Bacteria and viruses folder Use ‘Comparing bacteria table’ Complete ‘prokaryotes in evolution’, answers attached. Complete biozone sheet ‘Types of Living Things’ pg 127 Complete biozone sheet ‘Prokaryotic vs Eukaryotic cells’ pg 128 Complete ‘bacterial cells’ (this sheet was completed in IG level work scheme) Complete ‘cell theory timeline’, (saved as pdf and word) OR Cell theory Make statement that improvement in technology leads to new discoveries. Wk 1 Describe the ultrastructure of an animal (eukaryotic) cell (nucleus, nucleolus, ribosomes, rough and smooth endoplasmic reticulum, mitochondria, centrioles, lysosomes, and Golgi apparatus) and recognise these organelles from EM images. Read pages 136 to 139, complete Question 1 to 3 page 139. (text book). Definition of bold words. Use ppt ‘parts of cell’ review the cell organelles. Use ’ parts of cell student WS’ Edexcel As biology Revision guide, Read pg 52 to 54, complete Q 1 to 4, Thinking Task Q1 to Q3. Complete biozone sheet ‘Animal Cells’ pg 129 – 130. Use ‘animal cells’ 35 Organelles folder Complete ‘plant cells’ Handout ‘cell structure’ as summary notes Complete biozone sheet ‘Interpreting Electron Micrographs’ pg 137, part of resources saved as ‘interpreting electron micrograph’ Answers attached as ‘interpreting elc micr ans’ OR Complete ‘identifying cell structures’ OR Identify EM pictures of the organelles. Use ‘The cell EM pictures”, Teacher notes/instructions attached “The Cell teacher notes” OR information turn to ppt Complete biozone sheet ‘Identifying structures in an Animal Cell’ pg 138, saved as pdf ‘Id structures Animal Cell’ Complete ‘cell structure and function’ Complete ‘organelles assignment’, marking scheme ‘Marking Scheme for the Organelles Booklet A level’ Complete ‘Organelles’. Mention plasmids Wk 2 36 Explain the role of the rough endoplasmic reticulum (rER) and Complete ‘acetabularia exp’ Read pages 140 to 143, complete Question 1 to 4 page 143. (text book). Definition of bold words. Organelles folder the Golgi apparatus in protein transport within cells and including its role in formation of extracellular enzymes. Complete biozone sheet ‘cell structure and organelles’ pg 131 - 132 Complete biozone sheet ‘protein production and transport’ pg 145 Complete ‘cell processes’ Edexcel As biology Revision guide, Read pg 52 to 54, complete Q 1 to 4. Think task Q1 to 3. Complete ‘protein transport within the cell’ Revision Review organelles ‘organelle revision’ ppt. Students can use the PowerPoint and answer the questions on ‘Organelle Revision worksheet’ Organelles folder Topic test ‘organelles and microscopes’ Test folder Topic test ‘organelles and microscopes alpha tt’ Wk 2 Describe how the cells of multicellular organisms can be organised into tissues, tissues into organs and organs into systems. Read pages 144 to 145, complete Question 1 to 2 page 145. (text book). Definition of bold words. Use ‘Tissues’ ppt Make a table to summarise the different types of tissues on page 144. The table needs to include structure, functions and location. Complete biozone sheet ‘Levels of organisation’ pg 37 Tissue folder 139. Use board notes to cover the hierarchy of cells flowchart (add atoms to the flow chart). Relate to both plants and animals. For Plant tissue include Reproduction/ transport/ photosynthesis. Complete biozone sheet ‘animal tissue pg 140 Complete biozone sheet ‘Plant tissue’ pg 141 Review Wk 3 Explain the role of mitosis and the cell cycle for growth and asexual reproduction. Edexcel As biology Revision guide, Read pg 55, complete Q 1 to 2, Thinking Task Q1. Use ‘Tissue practise question’ for students to practise answering questions Read pages 146 to 147, complete Question 1 to 2 page 147. (text book). Definition of bold words. Make own notes. Use ‘cell cycle and mitosis’ ppt Read pages 148 to 150, complete Question 1 to 2 page 150. (text book). Definition of bold words. Make flow chart of stages, add the enzymes involved. Complete ‘the cell cycle’ Complete ‘stages in mitosis act’, answers attached. Use ‘stages in mitosis info’ for students to check 38 Tissue folder Cell cycle folder own answers or become part of their own notes while reading the textbook. Watch ‘Mitosis3’ clip. Complete biozone sheet ‘mitosis and the cell cycle’ pg 143-144. Use ‘apoptosis’ ppt Read pages 151 to 153, complete Question 1 to 5 page 153. (text book). Definition of bold words. Use ppt “Asexual Reproduction” Complete ‘Asexual Reproduction questions’ Reproduction folder Edexcel As biology Revision guide, Read pg 56 to 57, complete Q 1 to 4, Thinking Task Q1. Use ‘mitosis worksheet, as review Cell cycle folder Complete ‘mitosis flick book’ Ext ‘control of the cell cycle at checkpoints’ Wk 3 39 Describe the stages of mitosis and how to prepare and stain a root tip squash in order to observe them practically. Use ‘excel mitosis cell count’ Complete ‘observing mitosis exp’, teacher and technician notes attached. Marking scheme ‘Observing Mitosis Marking scheme’ OR Cell cycle folder View prepared slides of mitosis, For report students need Intro, Aim, flowchart of method they would of used if they used the recommended experiment, Results are the drawings and the discussion are the questions of the recommended experiment. OR Exp ‘observing mitosis’ Wk 4 Review Exp ‘mitosis cell count onion root tip’ Use ‘Mitosis practical test question’ has examiners report attached Explain the role of meiosis in the production of gametes and genetic Read pages 156 to 157, complete Question 1 to 3 page 157. (text book). Definition of bold words. Student Own notes variation through recombination of alleles and genes including independent assortment and crossing over (details of the stages of meiosis are not required). Cell cycle folder Cell cycle folder Complete ‘Mitosis and Meiosis’ worksheet Read pages 158 to 159, complete Question 1 to 2 page 159. (text book). Definition of bold words. Complete ‘Mitosis and Meiosis computer activity[1] (2)’ (online) OR Complete ‘cell cycle and dna online computer activity’ (extension) Use ppt ‘Meiosis’ Meiosis folder 40 Complete biozone sheet ‘meiosis” pg 148 Complete biozone sheet ‘mitosis vs meiosis’ pg 149. Complete biozone sheet ‘mendel’s laws of inheritance’ 150. (read only, do not do the questions) Exp: ‘chromosome assortment’ Complete biozone sheet ‘crossing over’ pg 151. Wk 4 Explain how mammalian gametes are specialised for their functions. Edexcel As biology Revision guide, Read pg 58, complete Q 1, Thinking Task Q1. Read pages 156 to 157, complete Question 1 to 3 page 157. (text book). Definition of bold words. Creep or read through with class and do a note taking exercise. Bacteria and viruses folder Show the clip ‘Bacterial Conjugation’ to show how the bacteria can reproduce. (pg 157) Read pages 160 to 161, Use ppt ‘Animal Gametogenesis’ Complete biozone sheet ‘gamete’ pg 153. Complete biozone sheet ‘gametogenesis’ pg 154. Complete ‘gametes and fertilisation’ Wk 4 41 Describe the process of Read pages 164 to 167, complete Question 1 to 4 Reproduction folder fertilisation in mammals and page 166. (text book). Definition of bold words. flowering plants (starting with the acrosome reaction in mammals and pollen tube growth in plants and ending with the fusion of the nuclei) and explain the importance of fertilisation in sexual reproduction. Use ‘animal Fertilisation’ ppt (some extended information at the end of the ppt. Reproduction folder Complete biozone sheet ‘fertilisation in mammals’ pg 155. Exp: ‘fertilisation in a marine worm’ Use ‘Journey of a human egg’ video clip cell growth differentiation Exp: ‘development of zebrafish’ Read pages 160 to 163, complete Question 1 to 4 page 163. (text book). Definition of bold words. Use ppt “plant fertilisation’ ppt Complete ‘alternation of generations’ Complete ‘modelling flowers’ Edexcel As biology Revision guide, Read pg 59, complete Q 1, Thinking Task Q1. Make sure that you read the examiners tip. Complete biozone sheet ‘fertilisation in flowing plants’ pg 156. Complete Q 2 and 3. Exp ‘observing pollen tube growth’ 42 Plants folder Use ‘Embryo development’ ppt Use ‘human development’ video clip Wk 4 Assessment/ Review Complete ‘Cells, tissues and cell division quiz’, answers attached ‘Cells tissues division quiz ans’ Cell growth differentiation Tests exams folder Use ‘Cell cycle and reproduction quiz’ Complete ‘Biozone Review Test 127 to 156’, answers attached ‘Bzone Rev Test 127 156 ans’ Complete ‘Cells and cell division essays’, marking scheme ‘Cells and cell division essays ms Wk 5 Explain what is meant by the terms stem cell, pluripotency and totipotency and discuss the way society uses scientific knowledge to make decisions about the use of stem cells in medical therapies (eg regulatory authorities relating to human embryo research, ability of stem cells to develop into specialised tissues, potential sources of stem cells, who could benefit from the therapies, procedures to obtain stem cells and their risks). Read pages 168 to 169, complete Question 1 to 2 page 169. (text book). Definition of bold words. Use ‘Totipotent Cells’ ppt. Use ‘Stem cells divide and are totipotent’ Read pages 170 to 171, complete Question 1 to 2 page 171. (text book). Definition of bold words. Own note exercise. Read pages 176 to 179, complete Question 1 to 3 page 179. (text book). Definition of bold words. Students make own notes. Use ‘Totipotency’ Read pages 180 to 181, complete Question 1 to 4 43 Review Questions folder Cell growth differentiation Folder page 181. (text book). Definition of bold words. Use ‘Who will benefit from stem cell therapy’ ppt. Discuss the use last paragraph, organs for transplant. Complete ‘ethical concerns stem cell research’ Read pages 182 to 183, complete Question 1 to 3 page 183. (text book). Definition of bold words. Students can read, own notes and complete questions. The questions (answers) will serve as their notes. Show stem cell clip ‘http://www.youtube.com/watch?v=5x8e2qsAVGc’ OR Show ‘Importance of stem cell therapy – YouTube’ OR Show ‘Miracle Stem Cell Cure- - YouTube’ Complete biozone sheet ‘stem cells’ pg 157. Complete biozone sheet ‘stem cell therapy’ pg 161 162. Answer the question: Judge the ethics on using stem cells. 44 gene technology folder Wk 5 Describe how totipotency can be demonstrated practically using plant tissue culture techniques. Edexcel As biology Revision guide, Read pg 62 to 63, complete Q 1 to 2, Thinking Task Q1. Read the Results plus. Complete biozone sheet ‘Plant Tissue Culture’ pg 163 - 164. cell growth differentiation Complete experiment ‘totipotency plant tissue’. Use mint and basil plants. Just use different size clippings. Use ‘Cloning Experiment’ For stock solutions use ‘PreparingStockSolutions’ or ‘plant culture totipotency’ OR Use the cloning kit OR Wk 5 Review Exp ‘plant tissue culture’ (assessment) Use ‘Stem cell, and pluripotency review test alpha’ (27 minute test) Test folder Go through the examiners report attached Wk 6 Explain how cells become specialised through differential gene expression, producing active mRNA leading to synthesis of proteins, which in turn control cell processes or determine cell structure in animals and plants (details of transcription factors 45 Use ‘ Read pages 154 to 155, complete Question 1 to 3 page 155. (text book). Definition of bold words. Use ‘Growth and development’ ppt Read pages 172 to 175, complete Question 1 to 4 page 175. (text book). Definition of bold words. Focus on the example on page 174 about the switch Growth and development folder are not required at AS). between γ-globin and ß-globin in embryo to baby. Use “Differential Gene Expression” ppt Complete biozone sheet ‘Differentiation of human cells’ pg 159 - 160. Do Q4 only. Gene Expression Folder Experiment ‘induction of b galactosidase’ saved as word & Pdf Wk 6 Review Wk 6 Explain how a phenotype is the result of an interaction between genotype and the environment (eg animal hair colour, human height, monoamine oxidase A (MAOA) and cancers), but the data on the relative contributions of genes and environment is often difficult to interpret. Use ‘Gene Probes’ ppt Gene Technology folder Complete ‘Biozone Review Test 157 to 160’ answers ‘Bzone Rev Test 157 to160 ans’ Read pages 184 to 185, complete Question 1 to 3 page 185. (text book). Definition of bold words. Tests exams folder Gene Expression Folder Use ‘Expression of genes’ ppt Use ‘gene or the environment AS’ Use ‘Barr Bodies’ ppt Ext ‘how one x chromosome is inactivated’ Use ‘Epistasis’ ppt Complete “Epistasis Problems’ Use ‘www.genome.iastate.edu/edu/genetics/epip1.html - Cached’ for one line questions. 46 Complete ‘epistasis’ pdf problems . Use ‘Gene Interactions’ ppt. Students make mind map of ppt. Edexcel As biology Revision guide, Read pg 60 to 61, complete Q 1 to 3, Read the examiners tips. Ext ‘sex determination; Read pages 190 to 191, complete Question 1 to 2 page 191. (text book). Definition of bold words. Students write definition on variation, use board notes to describe Standard variation Read pages 192 to 195, complete Question 1 to 5 page 195. (text book). Definition of bold words. Use ppt ‘Monoamine Oxidase A’ Enzymes folder Complete biozone sheet ‘sources of variation’ pg 165 - 166. Complete “genes or the environment’ Wk 7 Explain how some phenotypes are affected by alleles at many loci (polygenic inheritance) as well as the 47 Use ‘Cancer ‘ppt Cancer ppt Pg 176 Biozone. Read pages 188 to 189, complete Question 1 to 4 page 189. (text book). Definition of bold words. Data analysis folder environment (eg height) and how this can give rise to phenotypes that show continuous variation. Use ’ Studying Variation in Humans’ ppt Activity: ‘are we still getting taller’ Use “alleles’ ppt Molecular genetics folder Complete biozone sheet ‘gene-Environment Interactions’ pg 167 - 168. Complete biozone sheet ‘Polygenes’ pg 169 - 170. Read only, do not do the questions. Complete ‘polygenic inheritance’ Complete biozone sheet ‘gene interactions and gene inactivation’ pg 171 - 172. Complete biozone sheet ‘Inheritance in domestic cats’ pg 173 - 174. Complete biozone sheet ‘What geneotype has that Cat? pg 175 Review Wk 7 Review/ Assessment Edexcel As biology Revision guide, Read pg 64 to 65, complete Q 1 to 2, Thinking Task Q1. Read the Results plus. Complete questions 1 to 6 pages 196 to 197, (text book). Complete biozone sheet ‘Key terms: word find’ pg 146 Complete biozone sheet ‘Key terms: what Am I? ‘ pg 48 Tests exams folder 177 - 178 Complete ‘examzone unit 2 topic 3’ answers attached Review Topic 4: Biodiversity and natural resources Demonstrate knowledge and understanding of the practical and Edexcel As biology Revision guide, Read pg 68 to 69, complete Q 1 to 4, Thinking Task Q1. Read the Results plus. Complete ‘chech your notes topic 3’ Answers to textbook ‘unit2 topic4 ans textbk’ investigative skills identified in numbers 4 and 5 in the table of How Science Works on page 13 of this specification. Wk 1 Compare the ultrastructure of plant cells (cell wall, chloroplasts, amyloplasts, vacuole, tonoplast, plasmodesmata, pits and middle lamella) with that of animal cells. Read pages 200 to 203, complete Question 1 to 4 page 203. (text book). Definition of bold words. Review knowledge from topic 1 (cross linkage previously covered). As a class read pages 200 to 202, define the important notes {skills activity} Use ppt ‘plant cell structure’ Use ‘Plant Cell organelles’ ppt. Read pages 204 to 205, complete Question 1 to 3 page 205. (text book). Definition of bold words. Edexcel As biology Revision guide, Read pg 76 to 49 Review Questions folder Answers folder Plants folder 77, complete Q 1 to 2, Thinking Task Q1. Read the Results plus. Complete biozone sheet ‘Plant cells’ pg 180 Complete biozone sheet ‘Identifying Plant Cell Structure” page 181, do Q 1,2,3 Complete ‘plant and animal cells’ Wk 1 Compare the structure and function of the polysaccharides starch and cellulose including the role of hydrogen bonds between β-glucose molecules in the formation of cellulose microfibrils. Wk 1 Explain how the arrangement of cellulose microfibrils in plant cell walls and secondary thickening contribute to the physical properties of plant fibres, which can be exploited by humans. Wk 2 Compare the structures, position in the stem and function of sclerenchyma fibres (support) and xylem vessels (support and transport of water and mineral ions). 50 Complete biozone sheet ‘Cellulose and Starch’ pg 185 to 186 Organelles folder Biochemistry folder Use ‘AS cellulose structure’ (saved as word & pdf) Edexcel As biology Revision guide, Read pg 80 to 81, complete Q 1 to 2, Thinking Task Q1. Read the Results plus. Plants folder Use ‘AS SEM fibres in plants’ ppt Read pages 206 to 207, complete Question 1 to 2 page 207. (text book). Definition of bold words. Plants folder Use ‘plant stem structure’ Use ‘water transport in plants’ ppt, showing fibres pictures Plant transport folder Read pages 208 to 209, complete Question 1 to 2 page 209. (text book). Definition of bold words. Use ppt “Plant Transport’ Use ‘AS water transport in plants’ saved as word & pdf. There is an excel file with data ‘water transport in plants’ Read pages 210 to 211, complete Question 1 to 2 page 211. (text book). Definition of bold words. Use ‘Uptake of water by plants’ ppt Read pages 212 to 213, complete Question 1 to 3 page 213. (text book). Definition of bold words. Edexcel As biology Revision guide, Read pg 78 to 79, complete Q 1 to 2, Thinking Task Q1. Read the Results plus. Experiment ‘Conducting tissues exp’ Complete biozone sheet ‘Xylem and Phloem’ pg 187 Complete biozone sheet ‘Identifying Xylem Tissue’ pg 188 (reserve/optional) Complete biozone sheet ‘Transpiration pg 189 to 190 Complete biozone sheet ‘Uptake at the Root’ pg 191 51 Complete ‘Transpiration ws’ (review from IG course) Complete ‘Translocation ws’ (review from IG course) Complete ‘Uptake at the roots’ (old version) Complete ‘Root structure’ Wk 2 Describe how the uses of plant fibres and starch may contribute to sustainability, eg plant-based products to replace oil-based plastics. Complete ‘Stem structure’ answers attached Read pages 216 to 217, complete Question 1 to 3 page 217. (text book). Definition of bold words. No ppt, complete as class discussion and notes. Link the potato crop and monoculture to the problem of the Mauritius economy being based on sugar (85% of crop is sugar and is subsides by France- the subsides have stopped and now based on a deflated world sugar price) Read pages 218 to 219, complete Question 1 to 3 page 219. (text book). Definition of bold words. No ppt, complete as class discussion and notes. Read pages 220 to 221, complete Question 1 to 3 page 221. (text book). Definition of bold words. No ppt, complete as class discussion and notes. Make note that the problem with biodegradable plastics that is that they take a long time to breakdown. Exp: ‘superheating starch’ 52 Plants folder Edexcel As biology Revision guide, Read pg 82 to 83, complete Q 1 to 2, Thinking Task Q1 to 2. Complete biozone sheet ‘Bioplastics’ pg 184 Wk 2 Identify sclerenchyma fibres and xylem vessels as seen through a light microscope. Complete ‘Xylem and phloem’ OR Complete biozone sheet ‘Xylem and Phloem” pg 187 Plant transport folder Use ‘AS looking at plant stems’ saved as word & pdf Lab prep needed OR Experiment ‘Plant stems and roots act’ OR Look at different fibres in the light microscope. Make drawings of the xylem fibres OR Identify different plant cells tissue, use “Identifying Different Plant Tissue assign’ Plants folder OR Make a booklet that identifies the 3 plant tissue types in the stem, leaf and root. The booklet has the drawing and the function of the tissue. Wk 2 53 Describe how to determine the Complete ‘strength of plant fibre’, teacher and Plant folder tensile strength of plant fibres practically. Wk 3 Explain the importance of water and inorganic ions (nitrate, calcium ions and magnesium ions) to plants. technician notes available Use ‘AS extraction of plant fibres’ saved as word & pdf Read pages 214 to 215, complete Question 1 to 3 page 215. (text book). Definition of bold words. Read in class and make Board notes to state that biomass is organic. Ions are need for function. Summarise the information on page 214 in a table. Summarise the information on page 215 as a flowchart. Complete biozone sheet ‘Plant Mineral Nutrition’ pg 192 Wk 3 Describe how to investigate plant mineral deficiencies practically. Complete ‘invest plant deficiences’, teacher notes attached and technician notes attached. Have the plants growing in test tubes. Plant folder OR Complete ‘AS sick plants’ saved as word Complete biozone sheet ‘Plant Mineral Deficiencies’ pg 193 Wk 3 Describe how to investigate the antimicrobial properties of plants. Complete ‘antimicrobial plant prop exp’ teacher and Plant folder technician notes attached Use ‘AS garlic properties bacteria’ 54 Complete biozone sheet ‘Antimicrobial Properties of Plants’ pg 194 Wk 3 Complete ‘why put mint in toothpaste’ Dugs folder Read pages 222 to 223, complete Question 1 to 2 Plant folder Compare historic drug testing with page 223. (text book). Definition of bold words. contemporary drug testing protocols, Students make own notes eg William Withering’s digitalis soup; double blind trials; placebo; threephased testing. Use ‘Plant Pharmacies guided notes’ Read pages 224 to 227, complete Question 1 to 4 page 227. (text book). Definition of bold words. Students make own notes or slowly read through the book. Make sure they do the flowchart Complete biozone sheet ‘Testing new Drugs’ pg 195 to 196 Wk 4 Explain the terms biodiversity and endemism and describe how biodiversity can be measured within a habitat using species richness and within a species using genetic diversity, eg variety of alleles in a gene pool. Complete ‘testing a new drug’ Drugs folder Read pages 246 to 249, complete Question 1 to 4 page 249. (text book). Definition of bold words. Ecology folder Use ‘Biodiversity & Conservation’ ppt Use ‘as what is biodiversity’ saved as word & pdf Complete ‘as exploring biodiversity’ saved as word & pdf’ Ext: ‘simpsons diversity index’ 55 Ext: ‘estimating species numbers’ Read pages 228 to 229, complete Question 1 to 2 page 229. (text book). Definition of bold words. Use “species definition” ppt Use ‘AS the next bug thing’ saved as word & pdf Classification folder Use ‘as what is it species id’ saved as word & pdf Use ‘evolution of domains’ ppt, link to pg 230 Read pages 242 to 243, complete Question 1 to 3 page 243. (text book). Definition of bold words. Use ‘increasing biodiversity’ ppt natural selection folder Complete ‘the galapagos island AS’ saved word & pdf Use ‘AS toads genetic diversity’ saved as word &pdf Read pages 244 to 245, complete Question 1 to 2 page 245. (text book). Definition of bold words. Use ‘Endemism’ ppt Read pages 250 to 253, complete Question 1 to 4 page 253. (text book). Definition of bold words. Use ‘measuring biodiversity’ ppt Use ‘AS measuring biodiversity’, saved as word & 56 Ecology folder pdf. Complete biozone sheet ‘Global Biodiversity’ pg 200. Complete questions 7. Complete biozone sheet ‘Britain’s Biodiversity’ pg 201 to 202 Complete biozone sheet ‘Measuring Diversity in Ecosystems’ pg 203 to 204 (read only) Use ‘ Complete biozone sheet ‘What is a species’ pg 207 (reserve) Wk 4 Describe the concept of niche and discuss examples of adaptation of organisms to their environment (behavioural, physiological and anatomical). Edexcel As biology Revision guide, Read pg 70 to 71, complete Q 1, Thinking Task Q1. Read the Results plus. Read pages 234 to 235, complete Question 1 to 3 page 235. (text book). Definition of bold words. Ecology folder Use ppt’ The Ecological Niche’ Complete biozone sheet ‘Ecological Niche’ pg 208 Use ‘as ecology of leaf cutting beetle’ saved as word & pdf . Complete ‘as adaptations’ Wk 5 57 Describe how natural selection can lead to adaptation and evolution. Read pages 236 to 237, complete Question 1 to 2 page 237. (text book). Definition of bold words. natural selection folder Use ppt ‘Population Genetics’ Read pages 238 to 241, complete Question 1 to 5 page 241. (text book). Definition of bold words. Use ppt ‘natural selection’ Complete biozone sheet ‘Gene Pools and evolution’ pg 212 to 213 Complete biozone sheet ‘Founder Effect’ pg 214 Complete biozone sheet ‘Population Bottlenecks’ pg 215 Complete biozone sheet ‘Genetic Drift’ pg 216 Complete biozone sheet ‘Darwin’s Theory’ pg 217. (Read only). Complete biozone sheet ‘Natural selection’ pg 218 Exp: Use ‘as natural selection’ saved as word & pdf Complete biozone sheet ‘The Evolution of Darwin’s Finches’ pg 219 - 220 Use ‘deet resistant mossies’, answer or discuss the questions ‘deet resistant mossies Questions and tasks’ Complete ‘as well behaved beetles’ Edexcel As biology Revision guide, Read pg 72 to 58 73, complete Q 1 to 2, Thinking Task Q1. Read ‘pepper moth article’. Note how the referencing occurs. Students complete ‘Pepper moth article questions’ Read ‘pepper moth example’ which follows on from the article. The article ‘Second Thoughts about Peppered Moths’ explains why some people disputed the pepper moth example. Wk 6 Discuss the process and importance of critical evaluation of new data by the scientific community, which leads to new taxonomic groupings (ie three domains based on molecular phylogeny). The article ‘Selective bird predation on the peppered moth’ shows a prime example of critical peer review in the scientific community. Read pages 230 to 233, complete Question 1 to 3 page 233. (text book). Definition of bold words. Classification folder Use ‘molecular phylogeny and domains’ ppt Complete biozone sheet ‘The new tree of life’ pg 222 Complete biozone sheet ‘Phylogenetic Systematic’ pg 223 to 224 Use ‘AS being Darwin’ Complete ‘AS new ideas in biology’ saved as word & pdf Wk 6 Discuss and evaluate the methods used by zoos and seedbanks in the conservation of endangered species and their genetic diversity (eg scientific 59 Data analysis folder Ecology folder Read pages 254 to 255, complete Question 1 to 3 page 255. (text book). Definition of bold words. research, captive breeding programmes, reintroduction programmes and education). Use ‘Extinction’ ppt Read pages 256 to 257, complete Question 1 to 2 page 257. (text book). Definition of bold words. Use ‘Conservation’ ppt Read pages 258 to 261, complete Question 1 to 5 page 261. (text book). Definition of bold words. Read pages 262 to 263, complete Question 1 to 3 page 263. (text book). Definition of bold words. Complete biozone sheet ‘Biodiversity and Conservation’ pg 205 to 206. (students only read information) Complete ‘animal dating agency’ Complete ‘more than just saving seeds’ Complete ‘putting them back’ Ext ‘ant invasion’ Edexcel As biology Revision guide, Read pg 74 to 75, complete Q 1 to 2. Week 6 Review and assessment Ext ‘zoo health check’ Edexcel As biology Revision guide, Read pg 86 to 87, complete Q 1 to 5, Complete Question 1 to 4 page 264 to 265. (text book). 60 Tests exams folder Complete ‘Examzone unit 2 topic 4’ answers attached (assessment exam) ‘Examzone unit 2 topic 4 answers’ Complete ‘Unit 2 Topic 4 topic test’, answers ‘Unit 2 Topic 4 topic test ans’ Complete ‘check your notes topic 4’ Specimen Papers Unit 2 review/ Assessment 61 Edexcel As biology Revision guide, Read pg 88 to 91, Complete ‘bio GCE U2 jan 2011’, answers ‘ Review Questions folder Tests exam folder/ jan 2011 folder Complete ‘Bio GCE U2 Jun 09’, answers attached ‘ASbio unit1& 2 jun 09 ms’ Tests exam folder/ jun 2009 folder Complete ‘Bio GCE U2 Jan 09’ Tests exam folder/ jan 2009 folder Complete ‘Bio GCE U2 Jun 2010’, answers attached ‘Bio GCE U2 Jun 2010 ms’ Tests exam folder/ jun 2010 folder Complete ‘Bio GCE U2 Jan 2010’, answers attached ‘Bio GCE U2 Jan 2010 ms’ Tests exam folder/ jun 2010 folder Complete ‘Bio GCE U2 Jan 2012’, answers attached ‘Bio GCE U2 Jan 2012 ms’ Unit 3: Practical Biology and Research Skills *Unit code 6BI03 AS Students write a report of between 1500 and 2000 words, either a record of a visit to a site of biological interest or a report of research into a biological topic. Tests exam folder/ jan 2012 folder Edexcel As biology Revision guide, Read pg 92 to 95, Information in these pages designed to assist the student. Complete ‘bio GCE U3B jan 2011’, answers attached ‘bio GCE U3B jan 2011 ms’ Tests exam folder/ jan 2011 folder Complete ‘Bio GCE U3 jun 09’, answers attached ‘Bio GCE U3 jun 09 ms’ Tests exam folder/ jun 2009 folder 20% of the total AS marks 10% of the total GCE marks Complete ‘Bio GCE U3 jan 10’, answers attached ‘Bio Tests exam GCE U3 jan 10 ms’ folder/ jan 2010 folder 62 Complete ‘ASbio unit3B jan 08’, answers attached ‘ASbio unit3B jan 08 ms’ Tests exam folder/ jan 2008 folder Complete ‘Bio GCE U3B Jun 2010’, answers attached ‘Bio GCE U3B Jun 2010 ms’ Tests exam folder/ jun 2010 folder