D. Other Support Current Research Support: 1) National Institute of Health, NHLBI, 1KO8HL119592 Brewster (PI) Hanjoong Jo (Mentor) 4/141/19 This Clinician Scientist Mentored Grant identifies the molecular mechanisms of disturbed flow in arterial stiffening. 2) American Heart Association, Innovative Research Grant Brewster (PI) $150,000 1/1312/14 Angiogenic Potential of Adipose Tissue-derived Mesenchymal Stem Cells (ASC) from Ischemic Limbs. The goal of this project is to identify the barriers to angiogenic regeneration in ASCs from ischemic limbs. 3) Emory University/GTEC Regenerative Engineering and Medicine (REM) Seed Grant Brewster (PI) $32,000 9/128/13 Preconditioning Human MSCs from Amputated Ischemic Limbs for Autologous Clinical Application. The goal of this project is to optimize the in vitro culture of human mesenchymal stem cells from the bone marrow of amputated human limbs for subsequent use as cellular therapy in patients with limb ischemia. 4) Emory Children’s Center for Cardiovascular Biology Seed Grant Brewster (PI) $18,000 7/136/14 The Impact of Weight Loss on Arterial Health in Morbidly Obese Adolescents. The goal is to examine the impact of weight loss on arterial stiffness in morbidly obese adolescents. 5) Department of Surgery Research Laboratory Startup Funds. Emory University School of Medicine. Brewster (PI) Allan Kirk (Departmental Mentor) 7/117/14. Understanding the Mechanisms and Mechanics of Arterial Stiffening. Startup funding is granted to Luke Brewster for identifying molecular mechanisms involved in arterial remodeling. These funds support preliminary data collection for transition to scientific independence. Industry Funded Clinical Science 1. Investigator: Emory Site PI Source: Duke 2013Title: Unite-A Phase II, Single-Arm Prospective Study of the Safety and Efficacy of the UniFit Aorto-uni-iliac (AUI) Endoluminal Stent Graft for the Repair of Abdomial Aortic Aneurysms in Patients who are not Candidates for Repair with Commercially Available Bifurcated Endovascular Prostheses or Conventional Surgical Repair.