Supplemental Digital Content 3 – Figure 2 : Schematic representation of the experimental
design.
↑ sacrifice.
Study 1: vehicle: untreated isograft (n=7); DA donor: DA given to donors (n=6); DA recipient: DA given to
recipients (n=6); DA donor/recipient: DA given both to donors and to recipients (n=6); CEPO: CEPO given
to donors and to recipients (n=6); vehicle-3h: untreated isograft (n=3); CEPO-3h: CEPO given both to
donors and to recipients (n=3).
Study 2: vehicle2: untreated isograft (n=3); DA2: DA given both to donors and to recipients (n=4);
CEPO2: CEPO given to donors and to recipients (n=3).
Study 3: vehicle3: untreated isograft (n=3); DA3: DA given both to donors and to recipients (n=3); WT:
Wortmannin given both to donors and to recipients (n=3); WT/DA: Wortmannin and DA given both to
donors and to recipients;
Study 4: vehicle4: untreated allograft (n=6); DA4: DA given both to donors and to recipients (n=6);
CEPO4: CEPO given to donors and to recipients (n=6).