GETTING STARTED Life on Earth began almost four billion years ago with the formation of the first cells. Since then, cells have multiplied and changed to form the huge number of different organisms we see today. Over the past several hundred years, we have learned so much about the structure and function of cells that we are able to put cells to work in beneficial ways and fix or prevent many of the problems that affect cells. In Canada, scientists have modified cells so that they produce chemicals called antibodies that fight diseases such as cancer, leprosy, and tetanus (lockjaw). Other Canadian scientists have fused white blood cells (that produce antibodies) to cancer cells (that multiply rapidly) to create new, mixed cells. These cells produce larger quantities of beneficial antibodies than the white blood cells would produce on their own. When a person is burned, the skin in the affected area is destroyed. In the past, surgeons would replace burned skin with pieces of skin, called skin grafts, taken from unburned parts of the body. The grafts grow in the new location, but the area that the skin was taken from must also grow new skin cells. This was a painful process that can now be avoided with the use of artificial skin. Biologists grow artificial skin from skin cells incubated in petri dishes outside of the body. As a result, new skin grown in the laboratory can now be used to replace burned skin. Scientists have also been able to change one type of cell into another. For example, skin cells have been forced to change into bone cells and, in more recent advances, fat cells have been changed into nerve cells. These are important advances in medical technology as they could provide a treatment for diseases such as osteoporosis and Parkinson's disease. Modern cell research is conducted in laboratories all over the world. In addition to cell research, many laboratories, called diagnostic laboratories, conduct routine tests on samples of cells, tissues, and body fluids to determine the presence of disease or the type of disease a person or animal may have. A common medical laboratory procedure (called a biopsy) involves looking for cancer cells in a small sample of tissue that medical doctors remove from a patient's body. Other laboratories conduct studies on cells that are important in food and beverage industries. In these facilities, biologists, technicians, and technologists work as a team to discover more about how cells work and how they affect food processing. REFLECT on your learning 1. How has the microscope benefited the study of biology? 2. There are four major classes of biological compounds: carbohydrates, lipids, proteins, and nucleic acids. Which class includes compounds that cells use as a ready source of energy? to store energy? to store genetic information? 3. What will happen to the size of a cell that is placed in distilled water? Why? 4. The chemical reactions of life must occur at a relatively fast rate. Most chemical reactions double in speed with every 10ºC increase in temperature. (a) Why can’t living cells use large amounts of heat to speed up reactions? (b) How do cells increase the speed of chemical reactions without using large amounts of heat?