Research Assistant Nanobiophotonics and Imaging Research Group, School of Physics National University of Ireland Ref. No. NUIG 23-14 Applications are invited from suitably qualified candidates for a full-time fixed term position as a Research Assistant with Nanobiophotonics and Imaging Research Group, School of Physics at the National University of Ireland, Galway. This position is funded by Science Foundation Ireland (SFI) and is available from 1st May to contract end date of 31st January, 2015. Project Background The focus of this laboratory is to investigate minimally invasive novel optical methods for cancer detection and therapy using biophotonics applications and nanotechnology. Novel optical methods will be investigated using endoscopic catheter based in vivo cellular fluorescence imaging, Optical Coherence Tomography (OCT) and Surface Enhanced Raman Spectroscopy (SERS) and Imaging with novel bio-chemo-synthetic optical probes. The project will use optical on-line real time imaging systems implementing fluorescence/autofluorescence/diffuse reflectance with image processing software and endomicroscopic approaches to develop an optical biopsy techniques to stage cancer. The project will also develop nanophotonics approaches for protein and biomarker analysis for sensing and tracking cancer cells. Ex-vivo methods in multiphoton confocal fluorescence based cytology of biofluids combining the use of fluorescence life-time imaging to grade cancer will also be explored. Some transmission electron microscopy of cells will also be undertaken. Further details about the Nanobiophotonics and Imaging Research Group may be found at: www.nuigalway.ie/faculties_departmnets/physics/staff_pages/m_olivo Job Description: The successful candidate will assist in the development of in vitro assays to monitor the uptake and efficacy of nanoparticles in cancer cell lines with particular focus on the chick chorioallantoic membrane (CAM) model. The role also involves assisting in vivo efficacy studies involving post-mortem tissue processing using both light microscopy and electron microscopy techniques. Qualifications and essential Skills B.Sc in Chemistry or a related discipline A strong background in cell and molecular biology Have obtained full certification and training necessary for animal based biological research in accordance with Irish legislation Knowledge of tissue culture and use of animal models for biophotonics and nanotechnology applications Knowledge and experience of the cell physiological biological applications of nanoscale materials Knowledge of advanced light microscopy and some experience in electron microscopy Excellent verbal and written communication (English Language) skills Desirable skills and experience: M.Sc in Pharmacology or related discipline Evidence of scientific publication and dissemination of results at conferences Additional technical skills in histology and immuno chemistry Experience in Animal studies including CAM model Experience in surface characterization techniques Employment permit restrictions apply for this category of post Salary: € 23,181 – € 27,679 per annum (public sector pay policy rules pertaining to new entrants will apply) Start date: Position is available from 1st May, 2013 Further information on research and working at NUI Galway is available on Research at NUI Galway. For information on moving to Ireland please see www.euraxess.ie Informal enquiries concerning the post may be made to Professor Malini Olivo at malini.olivo@nuigalway.ie To Apply: Applications should be sent as a single file (in Word or PDF only) to Rebecca Nolan rebecca.nolan@nuigalway.ie and include; a covering letter stating the reason and suitability for applying for this specific position, a full curriculum vitae, and the names and contact details of at least three but not more than five referees who can be contacted for confidential references. Please put reference number NUIG 23-14 in subject line of e-mail application. Closing date for receipt of applications is 5.00 pm, 3rd March 2014 National University of Ireland, Galway is an equal opportunities employer.