Brighton Secondary College
SCIENCE TEST
Student name
Form
Genetics
Topic Test
Semester, Year
Reading Time
Five (5) Minutes
Writing Time
Forty (40) Minutes
Teacher
Structure of
this booklet
SKU
Section A – Multiple Choice Questions
10 Marks
Section B – Short Answer Questions
30 Marks
Section C – Extended Answer Question
20 Marks
Total Possible
60 Marks
RPI
Instructions
A single page, pre-prepared, hand-written reference sheet and a
scientific calculator may be brought into the test.
Progress Point &
Minimum Score
Science Knowledge & Understanding (SKU)
5.50
25-34 Demonstrates awareness of the importance of genetic information
5.75*
35-44 Demonstrates knowledge of the structure and function of DNA,
6.00
45-54 Explains the role of DNA and genes in cell division and genetic
to life.
genes and chromosomes.
inheritance.
Progress Point &
Minimum Score
Reasoning, Processing & Inquiry (RPI)
5.50
20-29 Uses information-processing skills in problem-solving activities
5.75*
30-39 Processes and synthesizes complex information in problem-solving
6.00
40-44 Processes and synthesises complex information to solve problems
that involve many variables.
tasks that involve many variables and possible solutions.
involving a wide range and complexity of variables and solutions.
Section A: Multiple Choice Questions
Circle the one most correct answer.
1
The two types of cells found in humans include gametes (sperm and eggs) and somatic cells
(the cells found in body tissues such as muscle, skin etc.).
The number of chromosomes in human gametes and somatic cells in that order are:
A 23, 46
B 23, 23
C 46, 46
D 69, 69
2
A child with down syndrome has the following karyotype:
The abnormal set of chromosomes are located in
A Set 2
B Set 8
C Set 21
D Set XX
3
In rabbits, the allele for long hair (h) is recessive to the allele for short hair (H). When a shorthaired female was mated with a long-haired male, the offspring consisted of five short-haired
and three long-haired rabbits. The genotypes of the parent rabbits must be:
A female (hh), male (HH)
B female (HH), male (hh)
C female (Hh), male (hh)
D female (Hh), male (HH)
4
When a cell undergoes meiosis, how many daughter cells are produced?
A 3
B 4
C 6
D 8
5
A strand of DNA has the base sequence CCTACTG. The complementary strand will have the
base sequence:
A GGATGAC
B AAGCAGT
C TTCGTCA
D CCTACTG.
6
John has genotype NN. His genotype would best be described as:
A homozygous recessive
B homozygous dominant
C heterozygous recessive
D heterozygous dominant
7
During one of Mendel’s experiments,

Generation I, true-breeding, long-stemmed pea plants were crossed with true-breeding,
short-stemmed pea plants.
 In Generation II all the plants were long-stemmed.
When the Generation II plants were cross-pollinated among themselves, the percentage of
short-stemmed pea plants in Generation III was likely to be
A 100%
B 75%
C 50%
D 25%
8
The pedigree below shows Huntington’s Disease which has a dominant allele. Two of the
children exhibit the symptoms of the disease.
The number of carriers of Huntingdon’s disease in generation II are likely to be
A 1 male, 2 female
B 2 male
C 3 female
D none
9
The genotypes and phenotypes for the ABO blood grouping system are shown below:
Genotype
IA IA
IA IO
IA IB
IB IB
IB IO
IO IO
Phenotype
(Blood Group)
A
A
AB
B
B
O
A male with blood type A and a female with blood type O produce a child. The child:
A must have blood type A
B must have blood type O
C may have blood type A or O
D may have blood type B.
10 The basis of accurate DNA replication is:
A specific base pairing rules
B the enzyme DNA synthetise
C the double helix nature of the molecule
D equal proportions of adenine and thymine
/10 Marks
Section B: Short Answer Questions
Write answers in the spaces provided
1) State the complementary base pairing rule?
____________________________________________________________________________
____________________________________________________________________________
____________________________________________________________________________
2 Marks
2) Complete a complimentary DNA strand for this DNA sequence;
ATTGCGCCATGCCCG
1 Mark
3) Draw a labelled diagram of the structure of a strand of DNA.
3 Marks
4) In terms of chromosomes, explain why a sperm or an ovum (egg) cannot possibly produce a new
human on its own:
________________________________________________________________________________
________________________________________________________________________________
________________________________________________________________________________
2 Marks
5) Explain the relationship between DNA, genes and chromosomes:
________________________________________________________________________________
________________________________________________________________________________
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________________________________________________________________________________
2 Marks
6) A brown animal is crossed with a white one. All the offspring are brown. What does this
suggest about the gene for brown colour in this organism?
____________________________________________________________________________
1 Mark
7) In the eye colour of vinegar flies, the trait for red eye colour (R) is dominant over the trait for
white eye colour (r).
(a) What colour are the eyes of a fly with the genotype Rr?
_________________________________________________________________________
(b) What are one or more possible combinations of alleles for eye colour in the zygote of a
white-eyed vinegar fly?
_______________________________________________________________________
1 + 1 = 2 Marks
8) Mendel discovered that in pea plants the green pea pod is dominant over the yellow pea pod.
a
Using G to represent the allele for green pods, and g to represent the allele for yellow
pods, write the genotypes for:
i
a homozygous plant with yellow pods: ____________________________
ii
a heterozygous plant with green pods: ____________________________
b
Complete the Punnett square to represent the cross of two plants heterozygous for pod
colour and state the resulting genotype and phenotype ratios.
Genotypic ratio:____________________________
Phenotypic ratio: ____________________________
1 + 1 + 1 + 1 + 1 = 5 Marks
9) The pedigree below shows the inheritance of a recessive disease caused by the allele (g). Those
with the allele that codes for the dominant trait (G) do not show the disease.
a
What is the genotype of an individual:
i
with the disease: _________
ii
heterozygous: __________
iii
without the disease:_______
b
What are the genotypes of each of the
following individuals?
i generation I female:________
ii generation II-2:___________
iii affected generation III female:____
iv generation II-3:___________
c
Explain how you arrived at your answer in question b, part iv, above:
_________________________________________________________________________
_________________________________________________________________________
_________________________________________________________________________
3 + 4 + 2 = 9 Marks
10) In terms of chromosomes, what is the difference between a male and a female?
_________________________________________________________________________
_________________________________________________________________________
1 Mark
11) The diagram at right shows the stages
occurring during a cell division.
a) State the name of this type of cell
division: _____________________
b) Suggest one type of cell that might undergo the type of cell division shown:
__________________________________
2 Marks
Section C: Extended Analysis
Write answers in the spaces provided.
1) The genetic disorder cystic fibrosis is caused by a gene on chromosome number seven. The
disease is recessive. Construct a punnet square in the space below and calculate the percentage
probability of the possible outcomes. Show your calculations.
(a) one parent has the disease and the other parent is not a sufferer or carrier of the disease
(b) neither parent has the disease but both parents are carriers of the disease
(c) neither parent suffers from the disease and one parent is a carrier?
3 + 1 + 1 + 1 = 6 Marks
2) Haemophilia is an X-linked recessive disease. The symbols used to show the relevant genes are
XH for the normal allele on the X chromosome, and Xh for the recessive allele on the X
chromosome.
a
State the possible genotypes of a:
i
haemophiliac male: _______________________________________
b
ii
non-haemophiliac male:____________________________________
iii
haemophiliac female: __________________________________
A female may be a ‘carrier’ of the disease.
i
What is meant by the term ‘carrier’?
____________________________________________________________________
____________________________________________________________________
ii
What is the genotype of a ‘carrier’ of Haemophilia?
____________________________________________________________________
5 Marks
3) Read the following article from ‘www.goldenrice.org’
a Briefly describe how the rice has been genetically engineered, being sure to mention four facts
mentioned in the article about this process.
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
4 Marks
b In your own words, state the concerns that this organisation has for the health of poorer people
and what it has suggested as a solution.
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
__________________________________________________________________________
3 marks
c Not all of the scientific community is supportive of such gene technologies. Details of the rice
were first published in the year 2000 however it is not currently available for human
consumption. Outline a potential benefit and a potential risk of this type of gene technology.
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
_____________________________________________________________________________
2 marks