Outline for Cells and Cell Membranes Honors Biology -- Mr. Ausema Gonzaga home page | Biology overview | Mr. Ausema's page | links I. History of cell-related discoveries A. 1600’s Hooke – first to describe cells (dead plant cells in cork) B. 1600’s Van Leewenhoek – first to describe one-celled microorganisms C. 1800’s Schleiden and Schwan – proposed the theory that all living things are made of cells. D. 1800’s Virchow – proposed the theory that all cells come from pre-existing cells (how does this tie in with Redi and his maggots?) Why are living things organized into cells? We will explore the answer to this question in lab. See p. 54-55, fig. 4.2 why are cells so small? How small are they? See p. 54, fig. 4.2. Also check out microscope information p. 52-54 | more here Tutorial on Scanning Electron Microscopes Virtual microscope cell videos II. Cell organization: organelles Also see overview chart p. 67 in your book. explore plant, animal, and bacterial cells with "iCell" explore the interior of a cell check out the virtual microscope fact sheet on cells - what we know and what we hope to learn in the future. animated cell anatomy and how it works Amazing cells - interactive exploration of cell interior and how cells work Animated video of cell activity | another animated video A. manufacture 1. nucleus – p. 58, fig. 4.5 2. ribosomes 3. endoplasmic reticulum (rough and smooth) 4. golgi apparatus – fig. 4.10, p. 61 5. flow of manufacture and processing – see fig. 4.13, p. 63 explore how vesicles work B. breakdown/catabolism 1. lysosomes – p. 62, fig. 4.11 2. vacuoles – p. 62, fig. 4.12 3. peroxisomes C. Energy processing 1. chloroplast – p. 64, fig. 4.15 2. mitochondria – p. 63, fig. 4.14 D. Support and movement 1. walls 2. cytoskeleton – p. 65, fig. 4.17 3. external matrix 4. junctions – p. 68, fig. 4.22 5. cilia/flagella – p. 66, fig. 4.18 How do cells communicate with each other? Organelle-related links III. Membrane structure: (see p. 74, fig. 5.1) | animated membrane structure | another animation exploration of membranes A. phospholipid bilayer - fig. 5.1 B. proteins – for transport and other functions – fig. 5.1B C. glycoproteins (carbo/protein combination) - serve as cell markers IV. Movement across the membrane: compare the membrane to a chain link fence (see p. 7579 in your book) Pictures and diagrams of movement across the membrane and membrane structure A. diffusion 1. definition: movement of particles across the membrane; results explained by kinetic molecular theory – p. 75, fig. 5.3 2. goes in the direction of the "gradient" – from higher to lower concentration. 3. only small, uncharged particles diffuse without assistance (examples: water, carbon dioxide, oxygen) B. osmosis - diffusion of water 1. also goes in the direction of higher to lower concentration; note that this means water tends to flow toward areas where solutes are more concentrated. (see fig 5-4, p. 76) 2. note results when cells are in solutions of greater or lesser concentration – sometimes the cells burst or collapse. (see fig. 5-5, p. 77) C. Facilitated diffusion (passive transport) (see fig. 5-6, p. 77) 1. involves particles moving across the membrane in the natural direction (high to low) 2. particles move through the protein "gates" because they are too large or too polar to diffuse through the lipid layer. 3. examples: sugar, some hormones, ions such as K+ and Na+ D. Active transport (see fig. 5-8, p. 78) 1. involves movement of any particle from low to high concentration ("against the gradient"), using the protein gates 2. called "active" because energy is needed *practice predicting which direction particles will flow E. Phagocytosis/Pinocytosis (see p. 79, fig. 5.9) IV. Variety of cells not all cells look like the "model cells" shown in your book. Some examples: A. Secretory cells (such as in stomach and intestines) B. Red blood cells C. Muscle cells D. Fat cells E. Nerve cells F. Leaf "pallisade" cells – photosynthesis G. Leaf transport cells V. Eukaryotic vs. Prokaryotic cells (see p. 55-57) A. Prokaryotic – bacteria – no "membrane-bound" organelles B. Eukaryotic – everything else. did mitochondria and chloroplasts used to be bacteria? (see p. 331, fig. 16.12) VI. Enzymes (p. 84-85) A. enzymes are proteins, so they are made of amino acids and have complex three-dimensional structure B. enzymes are biological catalysts. They lower the "activation energy" needed to start a reaction, so they make the reactions go faster. Enzymes control every chemical reaction that takes place inside living things. how do they do this? See fig. 5.12 and 5.14 C. enzymes are specific for particular reactions. Each step in a reaction process has its own enzyme. For example, getting the energy out of sugar (respiration) requires more than 20 separate enzymes. D. Enzymes can be sped up or slowed down by changing conditions such as temperature, pH, and concentration of reactants and products. (inhibitors - see fig. 5.16)