Preoperative Evaluation of the Cardiac Patient Consult Medicine 2011-2012 1. An 83 year old woman is admitted with a hip fracture and referred to you for preoperative evaluation. Her medical illnesses are hypertension and chronic atrial fibrillation. She takes hydrochlorothiazide/triamterene – one daily, amlodipine – 5 mg daily, and digoxin – 0.125 mg daily. On physical examination her BP is 140/100, heart rate 90 with an irregular rhythm, and respirations 20. She is obese, has JVD to the angle of her jaw at 30 degrees, and basilar crackles. There is a faint S3. Her BMP is normal except for a potassium of 2.8 and a calcium of 11.0 (albumin is 4.0). EKG shows LVH and atrial fibrillation with a ventricular response of 90. Assuming optimal perioperative care, what is this patient’s serious perioperative morbidity and mortality from the cardiovascular standpoint? A. 0.4% B. 0.9% C. 7% D. 11% 2. Besides replacing this elderly patient’s potassium, what else should be done to improve this patient’s prognosis at surgery? A. Advising non-operative treatment because of the high operative risks B. Delay of 1-2 days before surgery to optimize medical condition C. Admission to a monitored bed with placement of a pulmonary artery catheter D. Use of a beta blocker to decrease operative mortality E. Increase in amlodipine to more effectively control hypertension 3. A 60 year old man is seen in preoperative clinic for medical evaluation prior to a right femoral-popliteal bypass surgery. He denies any chest discomfort but says his right leg now hurts at rest, and he cannot walk more than 50 feet without stopping because of the pain. Up until two months ago he could walk up two flights of stairs slowly but without pain. He has a history of well-controlled type 2 diabetes mellitus requiring 35 units of 70/30 insulin twice a day, a myocardial infarction three years ago with cardiac catheterization showing right coronary stenosis of 75%, congestive heart failure with an echo done two months ago showing 30% ejection fraction and mild mitral regurgitation, hypertension, a chronic left bundle branch block, and Stage 3 chronic renal insufficiency. His medications include insulin, aspirin, lisinopril, furosemide, and metoprolol. His physical examination is remarkable only for normal vital signs, clear lung fields, a cardiac examination with a II/VI holosystolic murmur at the apex, and trace pedal edema. BMP reveals blood urea nitrogen of 35 and a creatinine of 2.9 which are stable. CBC shows only an hematocrit of 34, MCV of 82, and normal white blood count and platelet count. Previous iron studies were compatible with chronic disease. EKG shows the continued presence of a LBBB. What additional testing should be done before approving this patient for surgery. A. No additional testing is needed B. Dipyridamole/sestamibi scan C. Cardiac catheterization D. Implantation of a cardiac defibrillator and AV sequential pacemaker 4. A 75 year old patient is referred to you one evening from the observation unit for general medical evaluation prior to a TURP the following morning. He is asymptomatic except for urinary retention. On physical examination you detect a III/VI late-peaking systolic ejection murmur at the right second interspace with radiation to the clavicles. The murmur changes in pitch as you trace it down the left sternal border. There is a carotid-radial delay. S2 is diminished, carotid upstroke is slow, and there is an S4. LVH is present on EKG. Surgery under spinal anesthesia is planned for the following morning. What is the best set of recommendations to make to the surgeon at this time? A. Delay surgery for at least one day to obtain an echo with Doppler B. Proceed with surgery but recommend endocarditis prophylaxis C. Proceed with surgery but recommend general anesthesia D. Proceed with surgery but recommend continuous IV fluids at 150 cc/hour 5. A 40 year old man is referred to you for preoperative evaluation prior to a left inguinal hernia repair. He has no symptoms other than occasional bulging and pain at the hernia site. He has a II/VI systolic ejection murmur best heard at the left lower sternal border which increases with valsalva and decreases with handgrip. An EKG shows LVH. What is the one correct observation about this patient’s cardiac condition? A. An echo is unnecessary because the diagnosis is obvious clinically B. Use dopamine if hypotension occurs intraoperatively C. Myocardial infarction is the commonest cardiac complication perioperatively D. Family members should be evaluated for this patient’s heart condition E. A pulmonary artery catheter should be placed if general anesthesia is used 6. What are the indications for use of a pulmonary artery catheter in patients undergoing surgery? A. CHF with an EF of less than 35% B. Severe valvular heart disease C. Myocardial infarction within the last month D. All of the above E. None of the above 7. A 55 year old man who needs to undergo lumbar disk surgery is referred for evaluation of an irregular heartbeat noted on physical examination. He has no symptoms other than back pain with sciatica. A 24 hour Holter monitor reveals 10,000 PVCs with some couplets, triplets, and non-sustained ventricular tachycardia. Cardiac physical examination, TSH, echocardiogram, and dipyridamole-sestamibi testing are normal. What is the appropriate perioperative management of this patient? A. Initiation of a continuous esmolol infusion preoperatively and critical care monitoring for 24 hours postoperatively. B. Coronary arteriography to detect possible ischemic heart disease. C. Advise the surgeon there is no increased cardiac risk and to proceed with surgery. D. Advise postoperative telemetry for at least 24 hours. E. Place on oral beta blockers to suppress the palpitations. 8.A. A 74 year old man with hypertension and three-vessel coronary artery disease undergoes a total knee arthroplasty. He was advised two months ago to have CABS, but refused. He did agree at that time to having a bare metal stent placed in his 90% stenosed LAD. His medications include aspirin, metoprolol, amlodipine, and trazodone. His surgery is uneventful, and he is placed on telemetry because of his precarious cardiac status. What if anything should be done postoperatively to evaluate for myocardial injury? A. No cardiac evaluation should be done unless symptoms occur. B. Measure troponins in the recovery room and daily times two. C. Obtain EKG in the recovery room and daily times two. D. Obtain both troponins and EKGs as noted above. 8B. You elect to check troponins and an EKG, and the initial troponin returns at 3.5 and the EKG shows only non-specific ST-T wave changes. What is the proper management at this time (more than one answer is correct) - 12 hours after surgery. A. Cardiology consultation B. Cardiac catheterization C. Fibrinolytic therapy D. Low molecular weight heparin E. Unfractionated heparin F. Aspirin G. Beta blocker H. ACE inhibitor I. Statin J. Clopidogrel K. Echocardiogram L. Dip/Sesta scan 9. Which of the following antihypertensives should be held the morning of surgery to avoid perioperative hypotension assuming the blood pressure is normal that morning? A. ACE inhibitors B. Alpha-blockers C. Beta blockers D. Calcium channel blockers E. None of the above 10. Surgeries are usually delayed in patients whose systolic blood pressure is greater than 180 or diastolic pressure greater than 110. However, surgery may proceed with use of a quick-acting antihypertensive in what group of patients? A. Patients with a history of well-controlled hypertension B. Patients who have no cardiovascular comorbidities C. Patients younger than age 50 D. Patients with a normal EKG 11. Hypertension and congestive heart failure both occur in the perioperative setting. What are the two perioperative periods when these complications are most likely to occur? A. Induction B. Intraoperatively C. Recovery room D. Two days postoperatively 12. A 50 year old woman with a prosthetic metallic aortic valve must undergo an abdominal hysterectomy. There is no history of hypertension, diabetes mellitus, CHF, or stroke. She is currently on 5 mg daily warfarin therapy with an INR of 2.6. How should her anticoagulation be managed perioperatively? Assume in every case that DVT prophylaxis will be administered. A. Hold warfarin until INR falls to < 1.5, operate, and resume oral warfarin dose. B. Hold warfarin until the INR begins to fall, begin IV heparin to maintain APTT at 1.5-2.5 times control, and stop the heparin 6 hours preoperatively. Resume IV heparin along with oral warfarin at 12-24 hours after surgery and continue IV heparin until the INR is above 2.5. C. Hold the warfarin until the INR falls to < 1.5 and operate. Start IV heparin 1224 hours postoperatively along with oral warfarin. Stop heparin when the INR is above 2.5. D. Hold warfarin until the INR begins to fall, begin therapeutic low molecular weight heparin, and give the last dose of LMWH 12-16 hours preoperatively. Resume therapeutic LMWH 12-24 hours postoperatively along with oral warfarin. Stop LMHW when the INR is therapeutic. E. Continue the patient on warfarin and perform the procedure laparoscopically so that anticoagulation will not need interruption. 13. You are called to the recovery room to evaluate a 70 year old woman with new-onset atrial fibrillation and a ventricular response of 170. Her surgical procedure was resection of a lung nodule. She is lethargic but does not appear to have chest pain, and her blood pressure is 110/70. EKG shows no ischemia or infarction. Preoperatively she was on an ACEI for her hypertension and an SSRI for depression. What are correct statements about this patient? A. CABS would predispose to this arrhythmia. B. Immediate cardioversion should be performed. C. IV beta blocker is the most appropriate therapy for rate control. D. IV digoxin is the most appropriate therapy for rate control. E. IV heparin should be given immediately. F. IV adenosine triphosphate should be given immediately. G. Advanced age increases the risk for this arrhythmia perioperatively. H. If this patient had been undergoing cardiac surgery, a beta blocker or amiodarone preoperatively might have prevented this arrhythmia. I. ACE inhibitor use perioperatively reduces the incidence of this arrhythmia. 14. A 56 year old man with a near obstructing colonic adenocarcinoma is referred for preoperative evaluation. He admits to dyspnea on exertion after walking about one block, and on cardiac examination he has a III/VI crescendo-decrescendo murmur best heard at the right second interspace with radiation to his neck. Carotid upstroke is slow. Echocardiogram shows severe aortic stenosis with a gradient of 70 mm. What is the best course of action? A. Proceed with colonic resection B. Proceed with aortic valve replacement C. Perform balloon aortic valvuloplasty and then the colonic surgery D. Do not perform any surgical procedure and arrange hospice care E. Perform simultaneous aortic valve replacement and colonic surgery 15. A 38 year old woman with a cholecystectomy planned in one week for symptomatic gallstones is referred for preoperative evaluation because of a cardiac murmur. She notes mild dypsnea when doing housework. On examination she has a loud S1, a rumbling diastolic murmur over the apex, and a harsh third heart sound. What is the most common perioperative complication? A. Hypotension B. Congestive heart failure C. Atrial fibrillation D. Systemic embolization E. Myocardial infarction 16. A 68 year old patient with an AV sequential pacemaker undergoes a right total knee arthroplasty. During electrocautery use near end of procedure, his heart rate suddenly accelerates to about 120, and you as the internist performing his preoperative evaluation are contacted for advice. There has been no excessive blood loss and a stat EKG shows only a paced tachycardia. What is the most likely explanation? A. B. C. D. Reprogramming of the pacemaker induced by the cautery An anesthesia error resulting in too little sedation Adaptation of the pacemaker to perceived increased activity Shutdown of the pacemaker with resumption of the patient’s underlying rhythm 17. A 45 year old woman with type 2 diabetes mellitus and hypertension is admitted through the emergency room with a gluteal abscess. She takes hydrocholorothiazide 25 mg daily and atenolol – 50 mg daily along with bid 70/30 insulin. During surgery a fluid bolus is required to maintain her systolic blood pressure in the 90-100 range. You see her in the recovery room where her BP is 85/60, RR-16, T-98.8, and heart rate 60. She is mildly lethargic. Her heart and lung examinations are normal. SaO2 is 99% on 2 liters BNC. In addition to a fluid bolus and CBC what else is indicated at this time? A. B. C. D. E. Chest X-ray IV Narcan Blood cultures EKG CT Chest – PE protocol 18. An 82 year old man undergoes emergent surgery for ischemic bowel with about 25 cm of small bowel removed at surgery. He has known congestive heart failure with an ejection fraction of 35% and takes an lisinopril, furosemide, and spironolactone. He received several liters of IV fluid in the OR. On examination his blood pressure is now 241/139, pulse is 115, respiratory rate is 28, temperature 99.2, and SaO2 – 91% on 4L BNC. On examination he is mildly lethargic but is in some discomfort. He has bilateral crackles to mid- scapulae. Cardiac exam reveals an S3, S4, and tachycardia. In addition to a stat BMP, EKG, troponins, morphine, and 40 mg furosemide, what other medication would you consider at this time? A. B. C. D. IV enalaprilat IV diltiazem IV esmolol IV hydralazine 19. A 72 year old man comes to you for preoperative evaluation prior to scheduling a partial colectomy for adenocarcinoma of the colon. He has type 2 diabetes mellitus requiring insulin therapy. Functional capacity is poor because of osteoarthritis. There is no history of chest pain, dyspnea, pedal edema, or arrhythmia, but on EKG there are q waves present in II, III, and AFV. His CXR is normal. What is the best approach? A. B. C. D. E. No further cardiac evaluation prior to surgery Exercise treadmill testing Dipyridamole-sesamibi scan and echocardiogram Initiation of a beta blocker and approval for surgery Cardiac catheterization 20. If an exercise treadmill test indicates no residual ischemia, how soon is it safe to perform non-cardiac surgery on a patient with a recent myocardial infarction? A. B. C. D. One week Four to six weeks Two months Six months E. One year 21. A 55 year old man comes for preoperative evaluation prior to a laryngectomy. Four years ago he had CABG for left main disease. He denies chest pain, dyspnea, or any palpitations. He is able to climb 2 flights of stairs without a problem. Physical examination is unremarkable. An EKG unchanged from one year ago shows a LBBB. What additional testing should be done to evaluate his cardiac status? A. Echocardiogram B. Exercise treadmill test C. Dipyridimole/sestamibi scan D. Exercise treadmill test with radiopharmaceutical imaging E. No further cardiac evaluation needed 22. A 75 y.o. man is hospitalized for treatment of a hip fracture incurred when he fell over his dog. He has known hypertension and coronary disease and had two stents placed over a year ago. His medications are aspirin, metoprolol, rosuvastatin, and lisinopril. His hematocrit upon admission was 33.8 with an MCV of 83. His TIBC was 325, serum iron 60, and serum ferritin 197. Stool hemoccult is negative. He goes to surgery, and a CBC is now pending from the Recovery Room. In the Recovery Room he denies dyspnea, his BP is 115/75, and his heart rate 82. At what threshold of hemoglobin should he be transfused? A. Transfuse now given the expected hemoglobin drop B. <10 C. <9 D. <8 E. <7 23. A. A 55 y.o. man is referred to preoperative clinic prior to inguinal hernia repair. His small hernia which was discovered recently causes him occasional discomfort, but is thus far reducible. He has hypertension, insulin-requiring diabetes, hyperlipidemia and Class III angina. He is currently on a beta blocker, statin, sustained release NTG, aspirin, HCTZ, and an ACEI. An EKG is unremarkable. You refer the patient to Cardiology, and a catheterization is performed. Which one of the following cath reports would allow you to send the patient to surgery without CABS or PCI. A. RCA, circumflex, and LAD all have > 70% stenosis B. Left main artery has > 50% stenosis C. Two vessel disease with proximal LAD stenosis > 70% and EF < 50% D. Tight LAD disease alone E. All of the above require procedural intervention 23. B. The patient is found to have an 80% RCA lesion that proves symptomatically refractory to an increase in medical therapy. He is interested in having stent placement. What would be the best recommendation to make? A. Place drug eluting stent and then approve for hernia repair B. Place bare metal stent and then approve for hernia repair C. Perform angioplasy alone and then approve for hernia repair D. Perform hernia repair and then place drug eluting stent 24. A 63 y.o. man is referred for evaluation of chest discomfort prior to undergoing a colon resection for adenocarcinoma. His pain is pressure-like, substernal, related to activity, and is relieved by rest. He has the pain two times per week, and there is no recent change in severity or frequency. His only other medical illness is poorly controlled hypertension for which he takes HCTZ, amlodipine, and lisinopril. An EKG shows LBBB. What is the best non-invasive imaging modality to assess this patient's chest pain? A. Dobutamine stress echocardiography B. Dobutamine myocardial scan C. Dipyridamole/sestamibi scan D. Exercise myocardial perfusion imaging 25. Identify the patients who may be sent to surgery without further cardiac preoperative evaluation or treatment: A. 82 y.o. with hypertension, Stage III chronic renal disease, T2DM requiring insulin, congestive heart failure by history, and a remote stroke undergoing cataract extraction. B. 68 y.o. with Stage II angina, hypertension, and insulin-requiring diabetes undergoing open repair of an abdominal aortic aneurysm. He walks a half mile to church every weekend. C. 73 y.o. with hypertension, peripheral vascular disease, and a III/VI holosystolic murmur at the apex radiating to the axilla along with a soft S3. Lungs are clear. She is able to walk through a large supermarket doing her own shopping. She will undergo a femoral/popliteal bypass. D. 81 y.o. with iron deficiency anemia, Class III CHF with known diastolic dysfunction, Class II angina, and a positive stool hemoccult referred by GI prior to colonoscopy. 25. The POISE trial discouraged use of beta blockers acutely perioperatively because of increased mortality rates. The DECREASE IV trial suggested that bisoprolol might be used safely if started one month preoperatively with heart rate titration to 50-70 beats per minute. According to the revised 2009 ACC/AHA guidelines in which of the following scenarios can beta blockade be used with potential perioperative mortality benefit (Class I or IIA)? A. A 67 y.o. man with a planned open abdominal aortic aneurysm repair. He is on metoprolol daily for Class II angina. B. A 72 y.o. woman undergoing femoral/popliteal bypass surgery. She was experiencing some substernal chest discomfort with ambulation less than one block. She also has T2 diabetes mellitus and Class III chronic renal disease. Dobutamine stress echo shows reversible ischemia involving the RCA distribution. C. A 76 y.o. man who will undergo an elective total hip arthroplasty for DJD. He has well-controlled hypertension, congestive heart failure with an ejection fraction of 30%, and a history of stroke with minimal residual left hemiparesis. D. A 67 y.o. man undergoing endovascular repair of an abdominal aortic aneurysm. He is a heavy smoker (100 pack years) and has well-controlled hypertension. He does not have DM, stroke, known CAD, or CHF. However, his creatinine is 2.2 attributed to previously uncontrolled hypertension. E. A 78 y.o. woman with hypertension, Stage III chronic renal disease, history of stroke, T2DM requiring insulin, and CHF - diastolic dysfunction admitted with a hip fracture due to a fall at home.