Mitosis Miss Wineinger Review • What do genes code for? • How many chromosomes do humans have? • Chromosomes are made of _________ and _________. • Are your body cells haploid (1N) or diploid (2N)? Mitosis • 5 phases • • • • • Interphase Prophase Metaphase Anaphase Telophase • IPMAT 1. Interphase • Centrosomes and chromatids replicate inside the cell • All the chromatid is INSIDE the nucleus • Centrosomes are outside the nucleus 2. Prophase • Nuclear envelope disintegrates • Chromatin coils around the protein to make tightly wound chromosomes • Spindle fibers start from centrosomes and start to “reach” for chromatids 3. Metaphase • Replicated chromosomes line up in the center of the cell • Spindle fibers from the centrosomes “grab” chromosomes • Remember: Metaphase = middle 4. Anaphase • Sister chromatids are cleaved and become daughter chromosomes • Spindle fibers shorten • Remember: Anaphase = apart 5. Telophase • The last phase! • Spindle fibers disappear • Nuclear membrane forms around chromosomes • Remember: Telophase = The End Cytokinesis • NOT a step in mitosis • “cyto-” means ______ • “-kinesis” means ________________ • The two new, identical cells split • Chromosomes unwind back into chromatin Why? • Why do our cells undergo mitosis? Why? • Why do our cells undergo mitosis? • GROWTH AND TISSUE REPAIR! • What is one way to remember the phases of mitosis? • IPMAT!! Mitosis Animation • http://www.youtube.com/watch?v=-G-3BDlnK58