Mitosis

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• Prophase – Metaphase – Anaphase – Telophase
• Prophase
–
–
–
–
chromatin begins to tightly coil (condenses)
nuclear envelope begins to disappear
nucleoli disappear
each chromosome is now a complex of sister
chromatids
– mitotic spindle begins to form
– centrosomes move away fro each other
• Prometaphase
– nuclear envelope fragments
– microtubules move through the nuclear area
through the center of the cell
– each sister chromatid complex is now connected to
a microtubules by the kinetochore region of the
centromere
M-Phase
M-Phase
• Metaphase
– longest phase of Mitosis
– centrosomes are now at opposite
sides of the cell
– chromosomes are located at the
metaphase plate (center)
– kinetochores of the sister
chromatids are now attached to
tubules of opposite centrosomes
– microtubule complex is now
called the spindle
M-Phase
• Anaphase
– shortest phase of Mitosis
– sister chromatids are pulled
apart as the spindle fibers
shorten
– the separated chromosomes
migrate toward the opposite
poles
– at the end of anaphase the
polar regions of the cell have
equivalent amounts and
types of chromosomes
• Telophase
M-Phase
– the 2 daughter cell nuclei begin to
form
– nuclear envelopes begin to form
from the parent fragments
– chromosomes become less
condensed
– mitosis is complete with the
completion of the 2 nuclei regions
M-Phase
• Cytokinesis
– the cell divides at the cleavage
furrow shortly after Mitosis
• Pinching in of the plasma
membrane
– Cell plate forms in plants
• Becomes the cell wall
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