Global Sonographic Parameters In Portosystemic Shunts In 38 Dogs & Cats E Lindquist, D Casey, J Frank Eric Lindquist DMV , DABVP (Canine & Feline Practice) Director: Sound-Eklin New Jersey Mobile Associates Founder: SonoPath.com To Shunt Or Not To Shunt? That Is The Question. To Shunt Not To Shunt PV/CVC ≥0.75 and PV/AO ≥ 0.8. D‘Anjou et. al. Vet rad and US Vol 45, No 5 2004 102 pqtients Study Premise: Attempt to stabilize a reliable global and precise sonographic criteria to diagnose or rule out the presence of portosystemic shunting Study Design: Retrospective 5 Sonographers, Trained By 1 Single Evaluator Experienced in Dx Of PSS 33 Dogs & Cats with EHPSS 5 Dogs With Intrahepatic Shunts Age Range: 2 mo- 12 yr 19/38 Sx Confirmed Bile Acids: 93-473 umol/L US Evaluation of Bladder, Kidneys, Liver Size, PV:CVC and PV:AO Ratios Parameter 1: The Bladder Normal: No Calculi Or Sediment Calculi Or Sediment 24/33 (73%) EHPSS Cases. 2/5 IHPSS(40%). 68% overall. Parameter 2: The Kidneys Normal: No Renal Calculi Renal Calculi 32/33 (97%) Of EHPSS Cases. 3/5 for IHPSS(60%). 92% overall Parameter 3: Renomegaly EHPSS 29/33. 88% IHPSS 2/5. 40% 82 % Overall Parameter 3: Liver Size Normal: Subjectively Normal Liver Size Microhepatica 33/33 EHPSS. 5/5 IHPSS. 100% Of Cases Overall Parameters 4 & 5: Normal Portal Hilus; PV:CVC, PV:AO Ratios Normals: PV/CVC ≥0.75 and PV/AO ≥ 0.8. D‘Anjou et. al. Vet Rad US Vol. 45, No 5, 2004. 102 Patients Intrahepatic Shunt Parameters Bladder Sand/Stones: 2/5 Renal Calculi: 3/5 Renomegaly: 2/5 Microhepatica: 5/5 PV:CVC Ratio: 1:1 PV:AO Ratio: 1:1 CVC:AO Ratio: 1:1 Types Of Extrahepatic Shunts: 9 Gastrocaval (Looping), 18 Splenocaval (Short), 6 Splenoazygos (Long minimally curved) Caval Shunts: Increased Vena Cava Volume Gastrocaval Splenocaval Scanning Target: Excessive Vena Caval Volume For Gastrocaval & Splenocaval Shunts Caval EHPSS: 9 Gastrocaval & 18 Splenocaval Shunt Ratios (Normals PV/CVC ≥0.75 and PV/AO ≥ 0.8.) Gastrocaval: PV/CVC: 0.4-0.67 PV/AO: 0.4-0.71 Splenocaval: PV/CVC: 0.280.75 PV/AO: 0.4-0.78 Azygos EHPSS Shunt Parameters Azygos Shunt Bypasses The Cava Normal CVC:AO Ratio 6 Azygos Shunts: Normal Vena Cava Volume: Ratios: PV/CVC:0.4-0.63 PV/AO: 0.4-0.68 PV Pre/Post Shunt Differential Double Aorta PV/CVC Ratio 38 cases 1.2 1 0.8 0.6 0.4 0.2 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 PV/AO Ratio 38 Cases 1.2 1 0.8 0.6 0.4 0.2 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 Study Flaws Published Controls Non blinded Urolithiasis is a non specific finding Microhepatica & renomegaly are subjective parameters Caval probe pressure creates a variable Small number of cases (38) Conclusions In this population of 38 dogs and cats, the presence of : Urinary bladder sand/calculi, Renal mineralization Renomegaly Microhepatica were reliable, non exclusive, positive predictive factors for the presence of PSS , but do not distinguish IHPSS from EHPSS. Subnormal PV/CVC and PV/AO ratios (0.7 8 or less) are highly reliable indicators of the presence of EHPSS. Questions? Any Questions? Eric.Lindquist@ SonoPath.com