Dr/Ahmed Naseem BSc, MSc, iMLS(ASCP) Blood Bank, Tanta Cancer Center, Egypt introduction ❑ Immunohematology is the study of blood group antigens and antibodies, pretransfusion testing, identification of unexpected alloantibodies and autoantibodies, immune hemolysis, blood collection, blood components, cryopreservation of blood, transfusion-transmitted Viruses, blood transfusion practice, tissue banking and organ transplantation. ❑ In addition to safety, quality assessment, records, blood inventory management, and blood usage review. blood groups systems: ➢ ABO blood group system ➢ Rh blood group system ➢ Other blood group system: Kell, Duffy, Kidd, Lutheran, Lewis, Ii, P1PK, Globoside, MNS. Pretransfusion testing : ➢Antibody detection and identification, compatibility test. Transfusion practice: ➢Donor selection and phlebotomy, transfusion transmitted diseases, blood components preparation, transfusion therapy, complication of transfusion.