Pharmacology Generic: docusate calcium (OTC) Brand: Colace Class: Laxative, emollient; stool softener Dose: Adult: Adult: PO 50-400 mg/day in divided doses (sodium) or 240 mg q day (calcium); Rectal ENEMA 4 mL Route: Oral, Rectal enema Mechanism of Action: Increases water, fat penetration in intestine; allows for easier passage of stool Therapeutic Uses: Prevention of dry, hard stools Side/Adverse Effects: Bitter taste, throat irritation, Nausea, anorexia, cramps, diarrhea, Rash Nursing Considerations: Hypersensitivity, obstruction, fecal impaction, nausea/vomiting Nursing Assessment: Precautions: Pregnancy, breastfeeding Cause of constipation; identify whether fluids, bulk, or exercise is missing from lifestyle; constipating products Cramping, rectal bleeding, nausea, vomiting; if these occur, product should be discontinued Patient Education: That normal bowel movements do not always occur daily. Not to use in presence of abdominal pain, nausea, vomiting To notify prescriber if constipation is unrelieved or if symptoms of electrolyte imbalance occur: muscle cramps, pain, weakness, dizziness, excessive thirst That product may take up to 3 days to soften stools To take oral preparations with a full glass of water (unless on fluid restrictions) and to increase fluid intake Evaluation of Effectiveness: decrease in constipation