ACTIVE LEARNING TEMPLATE: Medication Example of a Sheet STUDENT NAME______________________________________ Acetylsalicylic Acid (Aspirin) MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________ CATEGORY CLASS__NSAID _____________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Produces analgesic and anti-inflammatory effect by inhibiting prostaglandins. May relieve fever through action in hypothalamus. In low doses intereferes with clotting by keeping a platelet aggregation substance to form. Therapeutic Use Osteoarthritis, mild pain, fever, suspected MI Complications CNS: Cerebral edema, coma, seizures, intracranial or subdural bleed. EENT: tinnitus, hearing loss GI: Bleeding, dyspepsia, pancreatitis GU ante/post partum bleeding HEMO leukopenia, thrombocytopenia, DIC HEP: hepatitis MET: hyperkalemia, metabolic acidosis OTHER Reyes syndrome Contraindications/Precautions Bleeding disorders, NSAID sensitivities, GI/Renal/hepatic dysfunction, acid-base or electrolyte imbalance, 3rd trimester or breastfeeding Interactions DRUG-DRUG: ACE inhibitors, beta blockers, corticosteroids, diuretics, heparin, ibuprofen, other NSAIDS, oral antibiotics DRUG-FOOD: Caffiene, ETOH Medication Administration Routes: PO or PR caps: 162.5mg, 325 mg tabs: 81mg, 325mg, 500mg May be enteric-coated to ext. release supp: 60mg, 120mg, 200 mg, 300mg, 600mg Nursing Interventions Enteric coated is not suitable for pain relief - slowly absorbed. PR-be alert to bleeding / irritation. Febrile and dehydrated will develop toxicity rapidly. Stop 5-7 days before procedures. Check LFTs, BUN, Cr, K, WBC, Platelets Client Education Evaluation of Medication Effectiveness Decrease NA diet Take with food Do not crush if enteric coated Depending on purpose: Reduction in mild pain or fever. Maybe used for therapeutic anticoagulation (check PT, PTT, INR) ACTIVE LEARNING TEMPLATES Therapeutic Procedure A7