The Well-built Clinical Question Case 1# Question Components Describe/Define P – Patient or Population Describe the most important characteristics of the patient. (e.g. , age, disease/condition, gender) I – Intervention; Prognostic Factor; Exposure Describe the main intervention. (e.g. drug or other treatment, diagnostic/screening test) C – Comparison ( if appropriate) Describe the main alternative being considered. (e.g., placebo, standard therapy, no treatment, the gold standard [RCT]) O – Outcome Describe what you’re trying to accomplish measure, improve, affect. (e.g. reduced mortality or morbidity, improved memory, accurate and timely diagnosis) The Well-built Clinical Question: Locate a professional peer-review journal article that provides sound reason and answers to your clinical question. Citation: APA 1 Case 2# Question Components Describe/Define P – Patient or Population Describe the most important characteristics of the patient. (e.g. , age, disease/condition, gender) I – Intervention; Prognostic Factor; Exposure Describe the main intervention. (e.g. drug or other treatment, diagnostic/screening test) C – Comparison ( if appropriate) Describe the main alternative being considered. (e.g., placebo, standard therapy, no treatment, the gold standard [RCT]) O – Outcome Describe what you’re trying to accomplish measure, improve, affect. (e.g. reduced mortality or morbidity, improved memory, accurate and timely diagnosis) The Well-built Clinical Question: Locate a professional peer-review journal article that provides sound reason and answers to your clinical question. Citation: APA 2 Case 1# A 29 year old man presented with history of injury to his right knee whilst playing sports resulting in a complete ACL tear. He underwent successful ACL reconstruction with a four strand hamstring tendon autograft. The graft was fixed on the femur using two bioabsorbable cross-pins and on the tibia with an Intrafix screw and sheath. The patient presented 13 months following the ACL reconstruction with symptoms of knee pain, locking and catching. He did not recall any specific injury to the knee which initiated these symptoms. Case 2# A 19-yr-old Division I college football player complained of acute onset of severe epigastric and right upper quadrant abdominal pain shortly after completing a 50-m sprint. The aching pain radiated to his upper back and was associated with progressive vomiting without blood, bile, or "coffee grind" emesis. He had been eating well before practice and hydrating without any pain or bloating. He denied any fevers, chills, diarrhea, headaches, food intolerance, or recent travel. He also denied the use of alcohol, tobacco products, drugs, or supplements. 3