Heredity and Society (Cell 103) Spring, 2010

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Heredity and Society (Cell 103)

Spring, 2010

Instructor:

Cherif Boudaba, Ph.D., [email protected]

; Phone: 862 8725

Office location: 4014 Percival Stern Hall, Office hours: Monday from 10:00 to

12:00 or by appointment

Class meets:

Tuesday and Thursday, 2:00-3:15 PM, Boggs 105

Course description:

This course focuses on modern concepts related to Human genetics. Student will learn how mutated genes induce birth defects, hereditary and non-hereditary diseases. Students will be familiar with tools used to manipulate genes.

Course learning outcomes:

After completion of this course, successful students will be able to:

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Describe genes and relate them to protein synthesis leading to genetic traits

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Explain the rules governing gene transmission to offspring and prediction of

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inherited traits

Understand gene mutation and relate it to inherited and non-inherited diseases

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such sickle cell anemia and cancer

Understand to which extend environment is involved in gene expression or its

-

-

damage

Describe the techniques used to manipulate genes

Use scientific knowledge learned to debate current social issues such as cloning, use of embryos in research, transgenic organisms, genetic testing, prenatal diagnosis…

Grades:

Grade determination is based on 2 midterms and a final exam worth equally (25% each), and homework (25%).

No makeup is given for any missed exam, except in case of sickness or death of an immediate family member; in both cases a written proof is required.

Textbook

: Yashon R. and Cummings M, Human Genetics and Society, First

Edition, Brooks/Cole, 2009.

Attendance:

Good attendance is important for success. Excessive absences are not tolerated and will affect student’s final grade.

Tentative lecture schedule

Date Topic Textbook chapter

21

26

28

January

12

14

19

9

11

16

February

2

4

18

23

25

March

2

4

9

11

Introduction and Overview

Cells

Cell division and Death

Development, Sex Formation

Reproductive Technology

Reproductive Technology and Ethics

Review

Midterm I

Mardi Gras

DNA Structure and Replication

Transcription and Translation

Chromosome

Meiosis, Sperm and Eggs Formation

Development, Birth Defect

Autosomal Gene Transmission

Sex-linked Gene Transmission

Biotechnology

Genetic Testing and Prenatal Diagnosis

BB1.1-BB1.4

11

2

1

1

2

2

No class

4

4, 5

3

4

4

6

7

15

20

22

27

8

13

April

1

6

May

4

25

30

16

18

23

DNA Forensics

Review

Midterm II

Human Genome Project

Spring Break

Spring Break

Review

Final exam (at 1:00 pm)

Polygenic and Multifactorial inheritance

Cell Cycle and Cancer

Behavior

Blood types, Organ Transplants

Genetics and Population

A Different World: Past, Present and Future

Of Human Genetics

8

9

No class

No class

10

11

12

13

14

15

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