The Small Animal Molecular Imaging Facility Contact: Mathew Thakur, Director Jefferson Alumni Hall, Room 474 215-503-7874, 215-503-1750 http://www.jefferson.edu/content/dam/tju/iacuc/SOP%20SmallAnimalMolecularImagingFacilit yProcedures.pdf Mission, Goals, Capabilities The mission of SAMIF is to facilitate the basic and translational research in which usage of small animals plays a prominent role. Facilitate can monitor and record biological interactions at molecular and cellular level in a living system and thereby allow longitudinal studies in the same species. These animals can serve as their own controls and allow investigators to monitor molecular interactions in vivo that may up regulate or down regulate disease processes. Goal: Goal of this facility is to provide the range of small animal imaging services to evaluate the different radiotracers and imaging agents in mice and rats models. Major Equipment - Services - Dedicated PET Scanner (Positron emission tomography) MicroSPECT (Single photon emission computerized tomography) MicroCAT II (Computerized tomography) Optical Imaging Multimodal imaging protocols for Oncology, Cardiology and Neurology Provides state-of-the-art in vivo molecular imaging Optical imaging with high resolution digital x-ray Bone density Studying patho-physiology and genesis of cancer. Evaluation of radiotracers and imaging agents Data analysis, quantification, region of interest (ROI), data interpretation. Comprehensive imaging services