MBI® Programme
2015-2016
Principles of Fermentation Processes
5-7 October 2015
Industrial Biotechnology: Biocatalysis
through to Synthetic Biology
18-20 April 2016
Rapid Fermentation Process Design: From
Development to Manufacture
26-28 October 2015
Analytical Data Analysis for the
Bioprocessing Industry
25-28 April 2016 (CPI, Darlington)
Downstream Processing – From Cell to
Column
16-19 November 2015
Stem Cell Training Course: Human
Pluripotent Stem Cells in Culture
25-27 April 2016
Downstream Processing –Chromatography
30 November-3 December 2015
Vaccines Bioprocess Development and
Commercialisation
17-19 May
Current Challenges in Mammalian Cell
Processing
25-27 January 2016
Bioprocess Design & Economic Evaluation
6-9 June 2016
Quality by Design for Effective Bioprocess
Characterisation and Validation
22-25 February 2016
Cell and Gene Therapy Manufacturing
1-3 March 2016 (Cell Therapy Catapult, London)
Design of Experiments for Bioprocess
Optimisation
7-9 March 2016
Bioprocess Facility Design
27-30 June 2016
Single Use Technology for Rapid
Manufacturing
11-13 July 2016
All courses held at the department of
Biochemical Engineering, University
College London unless otherwise
specified.
®
For up-to-date information on all MBI courses, visit
www.ucl.ac.uk/mbi
MBI® Awards
2012 IChemE Award for Training Innovation
2014 UCL Life Learning Enterprise Award for CPD and Short Courses
Downstream Processing:
Chromatography
Learn the most suitable purification operation for your
process and find out about new technologies on the horizon
30 November-3 December 2015
Est. 1994
Downstream Processing:
Chromatography
This module focuses on
product purification and,
through a series of lectures,
case studies and a pilot plant
session, will enable you to:
•Understand the principles of
72.3736
different methods of process
chromatography, including Packed
Bed, Monoliths, Expanded Bed,
Counter Current and Simulated
Moving Bed.
•Select the appropriate media for,
and predict the performance of,
chromatography separations upon
scale-up.
•Assess the suitability of affinity
separation as a product
purification operation and gain
awareness of advances in
rational ligand design for difficult
separations.
•Determine appropriate strategies
for the maintenance of column
and process hygiene.
•Consider how chromatography is
changing at industrial scale, and
which new technologies will have
an impact in the future.
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Who should attend?
This course is intended for
engineers, chemists, biologists,
biochemists and biotechnologists
who are interested in the
biochemical engineering aspects
of chromatography. Each concept
and topic covered will be explained
for the beginner - without assuming
detailed prior knowledge.
Typically, delegates are:
R&D scientists, engineers or
managers who need to
learn more about scale-up, scaledown and operation of
chromatographic methods in a
production environment.
95.1211
Day 1
•Introduction to module
•Chromatography
fundamentals
•Models and scale-up
•High throughput
chromatographic
bioseparations
•Pitfalls in the scaleup of packed bed
bioprocesses
•Social networking
dinner organised for
delegates and
speakers.
Day 4
•Process scale monoliths
•New approaches
to process scale
chromatography
•Case study: where
and when to apply
chromatography?
•Where will further
improvements in
chromatography come
from?
Day 2
•Pilot-plant studies:
chromatography
•Tailoring media for
bioseparations
•Affinity separation
•Design of biomimetics
for affinity separations
•Chromatography
practical results
Industrial Expert
Speakers Include
CMC Biologics A/S
Bio-Rad Laboratories GmbH
Brunel University
ABD Life Sciences Ltd
BIA Separations
Pall Corporation
GE Healthcare
Proxcys
Sartorius
Tarpon Biosystems
ProMetic Biosciences
Proxcys
For further information and bookings please contact:
E: mbi-training@ucl.ac.uk I Visit: www.ucl.ac.uk/mbi
T: +44 (0) 20 7679 9619 I +44 (0) 203 549 5619
Please note the agenda maybe subject to change.
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Day 3
•Process hygiene and
column maintenance
•Case study: mAb
purification; issues
in scaling-up to large
process scale
•Alternative approaches
to scaling up
•Design of small scale
columns for ease of
scale-up
•Simulated moving bed
chromatography for
biopharmaceutical
production
•Liquid - liquid
chromatography
Module Leader
Dr Daniel Bracewell
UCL