Use of Whole-Body MRI Systems for Animal Studies Advanced Imaging Research Center (AIRC) UT Southwestern Medical Center Upon completion, please submit form to: JeannieBaxter@utsouthwestern.edu Project Title: __________________________________________________________________________ Principal Investigator:___________________________________________________________________ Phone: ________________ Fax: _________________ Email: _________________________________ Primary Contact Person: ________________________________________________________________ Phone: _________________ Fax: _________________ Email: _________________________________ Project Description: (General goals/MR requirements) (Attach extra sheet if necessary) _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ Expected Beginning Date: _______________________________________________________________ Type of Study: One Time only ______________ Longitudinal _____________ Other _________________ Species and Number of Animals to be Imaged: (Approximate, if necessary)_________________________ _____________________________________________________________________________________ Do you have IACUC approval for MR Imaging? Yes _____ No _____ If yes, APN number: _________________________________________ *Attach copy of official acceptance letter from IACUC. Funding / Billing information: Funding Source: ____________ NIH Grant Number_______________ (For NIH reporting as a Shared Instrumentation Resource) UTSW Account: _____________________ Contact person for billing: ___________________________________ Address: ___________________________ Phone: ____________________________ Fax: ____________________________ Email: ____________________________ Non-UTSW: Contact person for billing: _________________________________ Billing address: _________________________________ _________________________________ Phone: ___________________________ Fax: ___________________________ Email: ___________________________ Do we have permission to use examples of the images obtained from your project for demonstrations of the system capabilities (without scientific description of the application)? Yes ______ No _________ Version 1 AIRC Assigned Animal Protocol #_________ 1/3 Advanced Imaging Research Center Standard Operating Procedures – Animal Use in Human Systems PREPARATION AND POST-PROCEDURE DISINFECTION OF HUMAN IMAGING AREAS UTILIZED FOR VETERINARY PROCEDURES PURPOSE: To clearly define proper procedures to prevent soiling and/or zoonotic agent transmission within human imaging areas during veterinary usage. DESCRIPTION: 1) All staff working with animals must wear gloves and any additional personal protective equipment (PPE) appropriate for the project. 2) All room preparation will be the sole responsibility of the investigator. a) All equipment and facility surfaces that may come into contact with animals must be completely covered with impermeable drapes during procedure. b) Floor drapes should be placed in surrounding work areas. c) Any fixed equipment in close proximity to the procedure should also be covered with a drape. 3) Animals will be inspected prior to moving to human imaging areas. Any feces or other materials noted on the skin, feet, or hooves of the animal will be removed and cleaned thoroughly with chlorhexidine or other approved cleaner. a) If unable to remove all organic matter or odors from the hooves or feet, they should be fully covered with vet wrap or an exam glove prior to movement into the room. 4) Animals will be placed on the transport cart within the ARC truck and covered with a sheet. The shells of the transport cart will be sprayed down with an approved ARC disinfectant before moving into the imaging area. 5) Once inside the human imaging area, the sheet over the animal will be carefully removed, folded, and placed on a covered surface away from the animal. 6) Animals will be transferred to the procedure table with a sling or other appropriate lifting device. Any animal greater than 50lbs should be moved by more than one person. 7) The entire surface of recovery cages brought into human imaging areas will be sprayed with an approved ARC disinfectant, including the wheels. 8) Animals will be promptly removed from the human imaging areas following the conclusion of procedures. 9) Decontamination and clean up: a) All drapes and gowns will be removed and placed in an appropriate waste container prior to removing gloves. All waste containers will be removed from the imaging areas for proper disposal. b) An approved ARC disinfectant will be used for wiping down all work surfaces. This includes any equipment surfaces potentially in contact with dander or fluids and all flooring within 6 feet of the primary procedure area. c) Care will be taken to ensure that all public areas are free from odor or animal debris. Version 1 AIRC Assigned Animal Protocol #_________ 2/3 Investigator Statement I have read the UTSW Advanced Imaging Research Center procedures for animal use and agree to conduct animal research accordingly. _____________________________________________ Principal Investigator’s Signature ___________________________ Date Human System Use for Animal Research: _____ I approve of the proposed use of human research facilities and equipment for animal research. _____ I do not approve of the proposed use of human research facilities and equipment for animal research. _____________________________________________ AIRC Medical Director Version 1 ____________________________ Date AIRC Assigned Animal Protocol #_________ 3/3