Use of Whole-Body MRI Systems for Animal Studies

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Use of Whole-Body MRI Systems for Animal Studies
Advanced Imaging Research Center (AIRC)
UT Southwestern Medical Center
Upon completion, please submit form to: JeannieBaxter@utsouthwestern.edu
Project Title: __________________________________________________________________________
Principal Investigator:___________________________________________________________________
Phone: ________________
Fax: _________________ Email: _________________________________
Primary Contact Person: ________________________________________________________________
Phone: _________________ Fax: _________________ Email: _________________________________
Project Description: (General goals/MR requirements) (Attach extra sheet if necessary)
_____________________________________________________________________________________
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_____________________________________________________________________________________
_____________________________________________________________________________________
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Expected Beginning Date: _______________________________________________________________
Type of Study: One Time only ______________ Longitudinal _____________ Other _________________
Species and Number of Animals to be Imaged: (Approximate, if necessary)_________________________
_____________________________________________________________________________________
Do you have IACUC approval for MR Imaging? Yes _____ No _____
If yes, APN number: _________________________________________
*Attach copy of official acceptance letter from IACUC.
Funding / Billing information:
Funding Source: ____________
NIH Grant Number_______________ (For NIH reporting as a Shared Instrumentation Resource)
UTSW Account: _____________________
Contact person for billing:
___________________________________
Address: ___________________________
Phone: ____________________________
Fax: ____________________________
Email: ____________________________
Non-UTSW: Contact person for billing:
_________________________________
Billing address:
_________________________________
_________________________________
Phone: ___________________________
Fax: ___________________________
Email: ___________________________
Do we have permission to use examples of the images obtained from your project for demonstrations of the
system capabilities (without scientific description of the application)? Yes ______ No _________
Version 1
AIRC Assigned Animal Protocol #_________
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Advanced Imaging Research Center
Standard Operating Procedures – Animal Use in Human Systems
PREPARATION AND POST-PROCEDURE DISINFECTION OF HUMAN IMAGING AREAS UTILIZED FOR
VETERINARY PROCEDURES
PURPOSE:
To clearly define proper procedures to prevent soiling and/or zoonotic agent transmission within human
imaging areas during veterinary usage.
DESCRIPTION:
1) All staff working with animals must wear gloves and any additional personal protective equipment (PPE)
appropriate for the project.
2) All room preparation will be the sole responsibility of the investigator.
a) All equipment and facility surfaces that may come into contact with animals must be completely
covered with impermeable drapes during procedure.
b) Floor drapes should be placed in surrounding work areas.
c) Any fixed equipment in close proximity to the procedure should also be covered with a drape.
3) Animals will be inspected prior to moving to human imaging areas. Any feces or other materials noted
on the skin, feet, or hooves of the animal will be removed and cleaned thoroughly with chlorhexidine
or other approved cleaner.
a) If unable to remove all organic matter or odors from the hooves or feet, they should be fully
covered with vet wrap or an exam glove prior to movement into the room.
4) Animals will be placed on the transport cart within the ARC truck and covered with a sheet. The shells
of the transport cart will be sprayed down with an approved ARC disinfectant before moving into the
imaging area.
5) Once inside the human imaging area, the sheet over the animal will be carefully removed, folded, and
placed on a covered surface away from the animal.
6) Animals will be transferred to the procedure table with a sling or other appropriate lifting device. Any
animal greater than 50lbs should be moved by more than one person.
7) The entire surface of recovery cages brought into human imaging areas will be sprayed with an
approved ARC disinfectant, including the wheels.
8) Animals will be promptly removed from the human imaging areas following the conclusion of
procedures.
9) Decontamination and clean up:
a) All drapes and gowns will be removed and placed in an appropriate waste container prior to
removing gloves. All waste containers will be removed from the imaging areas for proper disposal.
b) An approved ARC disinfectant will be used for wiping down all work surfaces. This includes any
equipment surfaces potentially in contact with dander or fluids and all flooring within 6 feet of the
primary procedure area.
c) Care will be taken to ensure that all public areas are free from odor or animal debris.
Version 1
AIRC Assigned Animal Protocol #_________
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Investigator Statement
I have read the UTSW Advanced Imaging Research Center procedures for animal use and agree to
conduct animal research accordingly.
_____________________________________________
Principal Investigator’s Signature
___________________________
Date
Human System Use for Animal Research:
_____ I approve of the proposed use of human research facilities and equipment for animal research.
_____ I do not approve of the proposed use of human research facilities and equipment for animal
research.
_____________________________________________
AIRC Medical Director
Version 1
____________________________
Date
AIRC Assigned Animal Protocol #_________
3/3
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