11.1.7 Discuss the benefits and dangers of vaccination Benefits • Possible elimination of the disease; smallpox • Decrease in epidemics and pandemics • More cost effective • Individual does not have to experience the full effects of the disease to get the immunity Dangers of Vaccinations • Many vaccines prior to 1999 contained thimerosal, a mercury based preservative. Mercury has been shown to be a neurotoxin to young children. • Many vaccines given at same time may cause an “overload” on the immune system • MMR vaccine may have a link to autism • Cases have been reported of vaccines leading to allergic reactions and autoimmune responses. Lesson 11.2 Muscles and Movement 11.2.1 State the roles of bones, ligaments, muscles and tendons and nerves in producing movement or locomotion • Bones - framework, levers, form blood cells, storage of minerals, protection . • Ligaments -tough band like structures that connect bone to bone • Tendons - cords of dense connective tissue connects bone to muscle • Nerves - carry impulse to muscles • All of these components come together to form a joint. • The science of kinesiology examines the movement of the human body. 11.2.2 Draw a diagram of the human elbow joint. • Identify: cartilage, synovial fluid, tendons, ligaments, radius, ulna, bicep, tricep. 11.2.3 Outline the function of each of the structures named in the elbow joint. • Tendons- connect bone to muscle. • Ligaments- connect bone to bone. • Humerous-acts as lever that allows anchorage of the muscles of the elbow. • Radius- acts as a lever for the biceps muscle • Ulna- acts as a lever for the triceps muscle. • Cartliage- reduces friction and absorbs compression • Synovial fluid- lubricates to reduce friction and provides nutrients to the cells of the cartliage • Joint Capsule- surrounds joint, encloses the synovial cavity and unites the connecting bones • Biceps muscles- contracts to bring flexion(bending) of the arm • Triceps muscles- contracts to cause the extension( straightening) of the arm 11.2.4 Compare the movements of the hip joint and the knee joint • The knee joint is a hinge joint. The joint is free moving- diarthrotic. Motions possible are flexion and extension. Angular motion in one direction. Convex surface fits into a concave surface. • The hip joint is a ball and socket joint. The joint is free moving- diarthrotic. • Motions possible are flexion, extension, abduction,abduction,cicumduction,and rotation. • Ball like structure fits into a cup-like depression. 11.2.5 Describe the structure of the striated muscle fibers, including the myofibrils with light and dark bands, mitochondria, the sarcoplasma reticulum nuclei and the sarcolemma • Straited muscle is also called skeletal muscle.. It moves the skeleton. • Muscles are made up of muscle fibers. • Muscle fibers contain multiple nuclei lie just inside the plasma membranesarcolemma • Sarcoplasmic reticulum is a fluid- filled system of membranous sacs surrounding the muscle myofibrils • Myofibrils are rod-shaped bodies that run the length of the cell. There are many of them and they run parallel to one another. They are closely packed and numerous mitochondria are squeezed between them. * Myofibrils are the contractile elements of the muscle cells and they are the reason that striated muscle has a banded pattern Myofibrils in Muscles 11.2.6 Draw and label a diagram to show the structure of a sarcomere. • Identify: sarcomere, light and dark bands, actin (thin) filaments, myosin (thick) filaments, sarcoplasmic reticulum. 11.2.7 Explain how skeletal muscle contracts by the sliding of filaments. 1) Calcum ions flood sarcoplasmic reticulum. 2) Myosin binds to ATPADP +PMyosin in high energy configuration (SET). 3) Actin/myosin cross-bridge forms. 4) Myosin releases ADP + Prelaxes to low energy state, cross bridge moves actin filament. 5) Myosin binds to new ATP releases cross-bridge. 6) ATPADP + PMyosin back in high energy configuration. Muscle Contraction Cycle 11.2.8- Analyze electron micrographs to find the state of contraction of muscle fibers