PERIPHERAL NERVOUS SYSTEM PNS Provides the relays to the central nervous system. It picks up sensory information from the environment and translates it to the CNS. The stimulus received by the PNS can be classified into five types. Classification of stimulus Mechanoreceptors respond to mechanical force such as touch, pressure (including BP), vibration, and stretch. Thermo receptors- are sensitive to temperature changes. Photoreceptors- such as those of the retina and the eye, respond to light energy. Chemorecptors- respond to chemicals in chemical solutions. (molecules that can be smelled, or tasted, etc) Noicreceptors- respond to stimulus that result from pain. Such as loud noise, extreme cold, pressure, and inflammatory chemicals. Classification by location Exteroceptors- sensitive to stimuli that occurs outside of the body. Needless to say, these receptors are found mostly on the body surface. Interoceptors- respond to stimulus within the body. They monitor everything from chemical change, tissue stretch, and temperature. They can make us feel pain, hunger, and discomfort, but we are usually unaware of it. Proprioceptors- Located in the skeletal muscles and joints , tendons and ligaments, and in connective tissue that covers the skeleton and muscle only. They serve the same function as interoceptors. Complexity Most PNS structures are simple, meaning that they are usually just a modified dendritic cell. The Few that are complex however, are what we associated as our sensory organs like the eyes. Sensory Integration: from sensation to perception Human survival depends not only on sensation, but the perception of that sensation. For example If you get smacked on the arm, you sense pressure, but you perceive that pressure as pain. General organization of the somatosensory system The somatosensory system is a system that serves the limbs of the body. The three main levels at which this is operated is as follows: Receptor level: sensory receptors (tells you what) Circuit level: Ascending pathway (Sends impulse to proper channel) Perceptual level: Neuronal circuits in the cerebral cortex (tells you how to perceive the stimulus.) Structural Classification of nerves A nerve is a cordlike organ that is part of the peripheral nervous system. The consist of parallel bundles of peripheral axons, enclosed by successive wrappings of connective tissue. Regeneration of Nerve Fibers 1. When a nerve is severed or crushed, Wallerian degeneration (cell destruction and the destruction of cells around the severed cell) occurs. 2. After debris is disposed of, Shwann cells proliferate and macrophages are released into the injury site. 3. Then the regenerated axons will sprout across the gap and to their original contacts. Cranial nerves There are 12 sets of nerves that associate themselves with the brain. They are: Olfactoral Optic Oculomotor Trochlear Trigeminal Abducens Facial Vestibulocochlear Glossopharyngeal Vagus Accessory Hypoglossal Cranial Nerves: Olfactory Sensory nerves that control smell. Runs from the nasal mucosa to the olfactoral bulb. Cranial Nerves: Optic Because the sensory nerves of vision develops outside the brain, it is a brain tract. Cranial Nerves: Oculomotor Sensory nerve that supplies nerves that innervate muscles that control eye movement. Cranial Nerves: Trochlear Means “pulley” and innervates muscles that are in a pulley shaped muscle in the orbit (eye area). Cranial Nerves: Trigeminal Three branches that supply sensory fibers to the face and motor fibers to the to the chewing muscles. Cranial Nerves: Abducens Controls the muscles that abduct the eyeball (move it laterally) Cranial Nerves: Facial A large nerve that innervates the muscles of the face. (and other things as well) Cranial Nerves: Vestibulocochlear Sensory nerve for hearing and balance. A.K.A. the auditory nerve. Cranial Nerves: Glossopharyngeal Means “tongue and pharynx”. Innervates the tongue and throat. Cranial Nerves: Vagus Means “wanderer” The only cranial nerve that extends to the thorax and the abdomen. Cranial Nerves: Accessory An accesory (helper) nerve that assists the vagus nerve. Cranial Nerves: Hypoglossal Runs inferior to the tongue and innervates the tongue muscles. Spinal nerves There are 31 pairs of spinal nerves that innervate the body. Each of those spinal nerves contain thousands of nerves. There are 8 pairs of cervical spinal nerves There are 12 pairs of thoracic spinal nerves There are 5 pairs of lumbar spinal nerves There are 5 pairs of sacral spinal nerves There is 1 pair of coccygeal nerves. Nerve plexus Are bundles of nerves that occur in the cervical, thoracic, lumbar, and sacral regions that are designed to innervate primarily the limbs. Branches of the cervical plexus: Cutaneous branches Branch Lesser occipital C2, C3 Supraclavicular C2, C3 Transverse Cervical C2 Greater auricular C3, C4 Structure served Skin on posterolateral aspect of neck Skin of ear, skin over parotid gland Skin on the anterior aspect of neck Skin of the shoulder and the clavicular region Branches of the cervical plexus: motor branches Branch Ansa Cervicalis C1-C5 Phrenic C1-C3 Segmental and other muscular branches C3-C5 Structure Served Infrahyoid muscle of the neck Deep muscles of the neck, portions of the scalenes, levator, scapulae, trapezius, and sternonucleiodmastoid muscles Diaphragm Branches of the brachial plexus Nerve Musculocutaneous C5-C7 Median: (2) branches MedialC8-T1 lateral C5-C7 Structure served Muscular branches; flexor muscles in anterior arm In cutaneous branches: controls skin on arm. Flexor muscles of the forearm. Digits of the fingers. Cutaneous: skin of 2/3 of hand and palm. Nerve Ulnar C8-T1 Structure served Flexor muscles of the anterior forearm; interisitc muscles of the lateral palm. Cutaneous branches: skin of the posteriolateral surface of the entire limb Nerve Radial C5-C8, T1 Structure Served Posterior muscles of the arm and forearm; most intrinsic muscles of the hands. Cutaneous: posteriolateral surface of the hand. Nerve Axillary C5,C6 Dorsal Scapular C5 Structure Served Deltoid and teres minor muscles. Cutaneous: some skin of the shoulder Rhomboid muscles and levator scapulae. Nerve Long Thoracic C5, C6 Pectoralis C5, C6 Suprascapular Structure Served Serratus anterior muscle C5-C7 Subscapular C5-T1 Teres major and subscapularis muscle Shoulder joint; supraspinatus and infraspinas muscles Pectoralis major and minor muscles Branches of the Lumbar plexus Nerve Femoral L2-L4 Obturator L2-L4 Structure served Skin of anterior and medial thigh. Medial leg and foot. Hip, knees, and joints. Motor to adductor magnus, longus, and brevis, obturator, skin for medial thigh, and for hip and knee joints Nerve Lateral femoral cutaneous. L2, L3 Iliohypogastric L1 Structure served Skin of lateral thigh; some sensory branches to peritoneum. Skin of lower abdomen and hip; muscles of anterolateral abdominal wall Nerve Ilioiguinal L1 Structure Served Skin of external genitalia, and proximal medial aspect of the thigh; inferior abdominal muscles Nerve Genitofemoral Structure Served Skin of scrotum in males, of labia majora in females, and of anterior thigh; inferior to middle portion of inguinal region; cremaster muscles in males. Branches of sacral plexus Nerve Sciatic nerve (including sural, medial and lateral plantar, and medial calcaneal branches) Tibial L4-S3 Structure Served Cutaneous branches: to skin of posterior surface of leg and sole of foot Motor branches: posterior of adductor magnus, triceps surae, tibulis Common fibular (superficial and deep branches) L4-S2 Cutaneous: to skin of anterior and lateral surface of the leg and dorsum of foot Motor branches: short head of biceps femoralis of the thigh; extensor muscles of the toes. Nerve Superior Gluteal L4, L5, S1 Inferior Gluteal L5-S2 Structure served Motor branch to gluteus medius and minimus Motor branch to gluteus maximus Posterior femoral cutaneous Skin of the buttock, and posterior thigh S1-S3 Pudendal S2-S4 Supplies most of the skin muscles, anus, clitoris, labia, vaginal mucosa (females), scrotom and penis in males.