For sophomores and juniors interested in medical school and undergraduate opportunities: • A visit by Dr. Paul Catalana, Al Squire, and other guests from Greenville Hospital System University Medical Center. • In RMSC 122 (The Pit) starting at 6:30pm, Tuesday Oct 30th. • Presentation and discussion on the new medical school at Greenville and undergraduate opportunities through their MedEx program, including clinical experiences and preparation for medical school. 1QQ # 21 for 10:30 Write each letter, and circle each correct response. a) Small motor units typically consist of Type II B myofibers. b) A motor unit will have at least two of the three types of skeletal myofibers. c) Sphincters are classified as tonically contractile. d) Muscle contraction in multi-unit smooth muscle is synchronized by gap junctions. e) Smooth muscles can contract even without a change in membrane potential. 1QQ # 22 for 11:30 Write each letter, and circle each correct response. a) Small motor units typically consist of Type II A myofibers. b) Large motor units generate greater tension than small motor units and are recruited first. c) Sphincters are classified as phasically contractile. d) Muscle contraction in singleunit smooth muscle is synchronized by gap junctions. e) Cardiac myofibers have action potentials and twitch durations that last about 1-2 milliseconds. S1 29 October 2012 Chapter 10: Control of somatic motor systems Riding a bike, playing piano, swinging a bat or golf club…. Video of Trampoline Championship Benjamin Zander: Classical Music and Shining Eyes Eric Mongrain playing Air Tap S2 Fig. 10.10a Each region has a homunculus S3 Fig. 10.02 Formerly called “basal ganglia”, consist of caudate, putamen, and globus pallidus Decision to move S4 Fig. 10.01 Initiates motor command Coordinates secondary movements Corticospinal and corticobulbar tracts Balance and complex learned movements Pathways? Other inputs: Vestibular & Visual! Reflex Examples of motor disorders: Huntington’s Disease and Cerebellar Disorder S5 Jack Nicholson One Flew Over the Cuckoo’s Nest Frontal lobotomy S 16 Pyramidal tract Fig. 10.12 Corticospinal tract Corticobulbar tract Fine motor control, esp. of extremeties Extra-Pyramidal tracts Reticulospinal tract Vestibulospinal tract Originate in brainstem, more involved with posture and equilibrium Not monosynaptic! Descending Pathways S 17 Who Cares? Video of Huntington’s Chorea Video of Cerebellar Dysfunction Video of Trampoline Championship Locked-in Syndrome S6 Local control • Muscle spindle Spindle Afferent gamma motoneurons – Stretch receptor – Intrafusal muscle fiber • What is their role? • The stretch reflex… – Follow the reflex arc – Be able to differentiate function of afferent fibers, alpha motor neurons, and gamma motor neurons Motor units of alpha motoneurons S7 Fig. 10.05ab This doesn’t happen! S8 Fig. 10.05c Co-activation of alpha and gamma motoneurons insures that the stretch of muscle can be detected regardless of the initial length or state of contraction of that muscle. S9 Fig. 10.06 Proprioception pathway via dorsal column-medial lemniscus pathway One component of Stretch reflex is monosynaptic Most common example: patellar reflex = “knee jerk reflex” Synergistic & Antagonistic S 10 Stretch Reflex Monosynpatic excitation of motoneurons of that muscle and synergistic muscles and polysynaptic inhibition of motoneurons to antagonistic muscles. Recall frog reflex lab and existence of spinal reflexes in single-pithed frogs. Also, example Christopher Reeve and patellar reflex. S 11 Fig. 10.07 S 12 Golgi tendon organs involved in a reflex to oppose excessive muscle tension. Not monosynaptic. Not shown: ascending axons in dorsal column-medial lemniscus tract. S 13 Joint angle detectors and cutaneous mechanoreceptors contribute to sense of body position (proproiception.) Plus vision and vestibular inputs! S 14 Crossed-extensor reflex: Common sense… check the book! S 18 Lifting a load and contraction velocity