Research Methods for the Social Sciences: An Introductory Course January 19th, 2010 – Class Introduction Division on Addictions, Cambridge Health Alliance Harvard Medical School Course Objectives Learn to critically evaluate empirical research Learn to identify critical components and potential pitfalls of research designs Learn to determine the appropriate research design for a given research question Gain the foundation to begin to design own research Course Schedule 1/19: Course Introduction (Sarah Nelson, PhD) 1/26: Research Design Overview (Heather Gray, PhD) 2/2: Research Design Part II – Data Collection and Procedures (John Kleschinsky, MPH) 2/9: Measurement and Validity (Julia Braverman, PhD) 2/16: Crash Course in Statistics (Evelyn Chao, PhD) 2/23: More on Design – Causality (Nelson) 3/2: The Context of Research (Debi LaPlante, PhD) 3/9: Ethics (Ryan Martin, PhD) 3/16: Practical Notes (Course Faculty) 3/23: Conclusion (Nelson) Course Webpage www.divisiononaddictions.org/methodscours e.htm (also available through the education section of the Division’s website) Powerpoints and suggested readings will be posted. You will need a password to access the material. Password is “methods”. Website will be functional by the end of this week. Assignment By the end of this week, please select one scientific article from your area of specialty that you would be interested in reading critically as part of this class. Email the reference to snelson@hms.harvard.edu. “It ain't what you don't know that gets you in trouble; it's what you know for sure that ain't so.” Mark Twain Witt, P. N. (1956). Die wirkung von substanzen auf den netzbau der spinne als biologischer test. Berline-Gottinger-Heidelberg: Springer-Verlag. NAME THAT DRUG! 1) Hashish 2) LSD A. B. 3) Caffeine 4) Mescaline C. D. NAME THAT DRUG! 1) Hashish 2) LSD A. Hashish B. LSD 3) Caffeine 4) Mescaline C. Caffeine D. Mescaline Baseball & Science “Baseball—of all things—was an example of how an unscientific culture responds, or fails to respond, to the scientific method” Michael Lewis, Moneyball, 2003, p.xiv How Do Baseball Scouts Typically Identify “Talent”? “…there was a bias toward what people saw with their own eyes, or thought they had seen. The human mind played tricks on itself when it relied exclusively on what it saw… There was a lot you couldn’t see when you watched a baseball game” (Lewis, 2003, p.18) Revised Models of What Predicts Winning in Baseball Runs scored is best predictor of winning Best predictor of runs scored is on-base %, not batting average, ERA, defense, etc. What Does Baseball Have to Do with Research Methods? If our eyes can deceive us to thinking that certain key “baseball” factors are important, when often they are not, then… Our eyes can deceive us similarly to thinking that certain key factors are integral to other behaviors we observe or experiences we study, when often they are not A Bald Girl? Often our definitions of concepts rely on non-integral aspects of those concepts. Marlo Thomas and Friends, 1974. Free to Be, You and Me Flawed Research “Cute feet, small, dainty, yup, I’m a girl” – [No comparison group] “Bald – you’re bald, fella, bald as a ping pong ball” – [Predictive at one age, not all] “You’re bald, too!” “Yech, a bald girl – disgusting.” – [Dropping initial assumption in order to support theory] “You just shaved, right?” “Wrong!” “Exactly!” – [Could have used evidence either way] The Dangers of CHC 1. 2. 3. 4. More than 98 percent of convicted felons have tested positive for CHC. CHC is associated with all the major diseases of the body. For example, nearly all sick people have ingested CHC. The effects are obviously cumulative: 99.9% of all people who die from cancer have ingested CHC. 99.7% of the people involved in auto accidents used a substance containing CHC within 6 months preceding the accident. 93.1% of juvenile delinquents come from neighborhoods where CHC is used frequently. From Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) The Dangers of Bread 1. 2. 3. 4. More than 98 percent of convicted felons are bread users. Bread is associated with all the major diseases of the body. For example, nearly all sick people have eaten bread. The effects are obviously cumulative: 99.9% of all people who die from cancer have eaten bread. 99.7% of the people involved in auto accidents ate bread within 6 months preceding the accident. 93.1% of juvenile delinquents came from homes where bread is served frequently. From Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Konrad Lorenz (Austrian ethologist) “It is a good morning exercise for a research scientist to discard a pet hypothesis every day before breakfast. It keeps him young.” On Aggression, ch. 2 (1963; tr. 1966). Problems with Personal Experience We tend to seek information that is consistent with our beliefs and ignore inconsistent information (bald girl) We tend to base our inferences on little information (anecdote) Our expectations tend to influence what we see (bald girl, CHC) We’re not attentive to base rates and comparisons – We overlook the fact that inferences about contingencies require some kind of comparison or standard. (CHC) Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Problems with Personal Experience The confirmation bias helps to ensure that, once an expectation or theory has been developed, the belief will be selfperpetuating. Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) The Scientific Method The scientific method is a way of dealing with these concerns. Science is the process of constructing, testing, and refining theories about natural phenomena though the use of systematic empirical observation. Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method, Defined The collection of data through observation and experimentation and the formulation and testing of hypotheses. (Merriam-Webster’s Dictionary) Scientific Method as SelfCorrecting theory about how something works generate predictions testing: comparing the observations with the theory (what would the theory lead you to observe?) systematic empirical observations Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method as SelfCorrecting theory about how something works testing: comparing the observations with the theory ensures that inconsistent observations will be recorded generate predictions (what would the theory lead you to observe?) systematic empirical observations Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method as SelfCorrecting theory about how something works testing: comparing the observations with the theory ensures that inconsistent observations will be counted against the theory generate predictions (what would the theory lead you to observe?) systematic empirical observations Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method as SelfCorrecting theory about how something works testing: comparing the observations with the theory theory is revised in light of the tests, and, hopefully, becomes more accurate generate predictions (what would the theory lead you to observe?) systematic empirical observations Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method Theory – An organized set of principles that describes, predicts, and explains some phenomenon. Hypothesis – A specific testable prediction, often derived from a theory from Kassin, 1998, Psychology (2nd Edition). Scientific Method Science is a process for understanding the world. It is not a topic or subject matter. Some people believe that chemistry, for example, is inherently scientific. However, one can study chemical phenomena in scientific ways or in non-scientific ways. Adapted from Fraley, C. (http://www.uic.edu/classes/psych/psych242f/spring2004) Scientific Method Step 1. Observe behavior or other phenomena Induction – Involves using a relatively small set of specific observations as the basis for forming a general statement about a larger set of possible observations. People at Cambridge Health Alliance are not very interested in learning about research methods Adapted from research methods lecture by Julia Braverman Scientific Method Step 2. Form a Tentative answer or explanation Initial Hypothesis People at Cambridge Health Alliance do not sign up for research methods because they do not value science Adapted from research methods lecture by Julia Braverman Scientific Method Step 3. Use hypothesis to generate a testable prediction Deduction (From big to small) – Uses a general statement as the basis for reaching a conclusion about specific examples. If people at CHA do not sign up for research methods because they do not value science, then changing the date, time, or location of the class should not alter enrollment. Adapted from research methods lecture by Julia Braverman Scientific Method Step 4. Evaluate the prediction by making systematic planned observations – Compare the predictions with observations. Changing the date, time, and location increased enrollment significantly Lack of agreement: – Revise the hypothesis People at CHA do not sign up for research methods if it is not located at Cambridge Hospital Adapted from research methods lecture by Julia Braverman Scientific Theory Planned observations New prediction New hypothesis Planned observations Prediction Observation Adapted from research methods lecture by Julia Braverman Hypothesis Evaluating Research Is the evidence being forced to fit the hypothesis? Is the interpretation appropriate, given the results? What can the study tell us about the relationships it measures? What unmeasured variables might affect the results? Exercise: Jumping to Conclusions In each of the following situations, the conclusion may be erroneous or is not justified by the facts. In the space provided, describe the error or errors in thinking or methodology that invalidate the conclusion and suggest changes that could be made in the study that might allow for the conclusion given. A clinic sponsoring a Stop Smoking treatment program surveys all the people who completed the program during its first year. The survey revealed that 74% of the respondents were still not smoking three months after completing the program. In their next advertising campaign, they claim a 75% success rate for those who enroll in their program. Copyright © 1996 Andrew Geoghegan Exercise: Jumping to Conclusions In each of the following situations, the conclusion may be erroneous or is not justified by the facts. In the space provided, describe the error or errors in thinking or methodology that invalidate the conclusion and suggest changes that could be made in the study that might allow for the conclusion given. An investigator gave a personality test to a large number of crack cocaine addicts. The addicts scores on the trait of "emotionality" were significantly lower than the scores on that trait obtained from the general population. This caused the investigator to believe that highly unemotional people are more susceptible to crack cocaine addiction. Copyright © 1996 Andrew Geoghegan Media Headlines Soda consumption could lead to medical problems (wvec.com) 2. Kids' Urge To Drink Boosted By Outdoor Alcohol Ads (Medical News Today) 3. Teen Girls Using Pills, Smoking More Than Boys (Washington Post) 1. Soda consumption could lead to medical problems An all-American drink, soda, is now raising some real medical concerns according to a new study. A Framingham Heart study of more than 6,000 people was released Monday afternoon. According to it, if you’re middle-aged and drink more than one soda a day, you may have a more than 40% greater rate of either having or developing metabolic syndrome; a cluster of conditions that increase the risk of heart disease. Researchers discovered that people who drank one or more sodas each day had a 30% increased risk for obesity, a 25% greater risk for abnormal blood sugar levels and a 32% increase in the odds of having low levels of good cholesterol. All three contribute to heart disease. Former Ghent resident Tim Minger is already cutting back, which is why he and his wife didn’t drink soda at their Monday lunch. His wife, Agnes, say Tim's soft drink addiction was really bad. "Like a twelve pack, ok, every other day a twelve pack of Mountain Dew,” said Agnes Aldana. “I'm sort of addicted,” said Tim. “I drink at least everyday. I've recently switched to diet. That's my concession. Here's the clincher; researchers say even drinking diet soda may increase the risk of heart disease. They can't explain why. The researchers say it's worth noting that people who drink both regular and diet soft drinks have a tendency to eat the same kind of food. This study on soda is published in the on-line edition of the Journal of Circulation. Kids’ urge to drink boosted by outdoor ads In the world depicted in an alcohol billboard, bikini-clad babes clutch icy bottles, frothy beer flows over frosty mugs and the slogan reads, 'Life is good.' Ads like these may target adults, but children are getting the message too, a University of Florida and University of Minnesota study shows. Adolescents attending schools in neighborhoods where alcohol ads litter the landscape tend to want to drink more and, compared with other children, have more positive views of alcohol, researchers report in the Journal of Studies on Alcohol and Drugs. UF and UM researchers counted the number of alcohol ads within a two-block radius of 63 Chicago schools and compared students' opinions on drinking when they were in sixth grade and again two years later. The result - The more ads for alcohol there were in a neighborhood, the more students were interested in drinking alcohol, the findings show…. ….About half of all teens sample their first alcoholic drink by the time they are 15, according to the U.S. Surgeon General, which released a report on teen drinking earlier this year. Teens who start drinking this early are more likely to have trouble in school, become addicted to alcohol, smoke cigarettes and use drugs than adolescents who don't drink, the report states…. …."I think results from this study and studies like this study clearly indicate that there should be policies to ban alcohol advertising near the schools," Komro said. "It clearly shows that exposure is dangerous for our children." Teen girls using pills, smoking more than boys Teenage girls, having caught up to their male counterparts in illegal drug use and alcohol consumption, now have the dubious distinction of surpassing boys in smoking and prescription drug abuse. In the past two years, in fact, more young women than men started using marijuana, alcohol and cigarettes, according to government findings being released today. The results are doubly disturbing, researchers said, because they run counter to trends indicating an overall decline in teenage drug use and because young women appear to suffer more serious health consequences as a result. Critique found at stats.org For further information: • snelson@hms.harvard.edu • www.divisiononaddictions.org • A copy of this presentation will be available online (through the “Education” link) by January 22nd • www.basisonline.org • Online review of current research in addictions • (alcohol, tobacco, illicit drugs, gambling, and humanities) Addiction resources