ENDOCRINE PROJECT By: Katie Glaeser Melanie Olmedo 8th January 13, 2014 Female Gonads (ovaries) The female gonads (ovaries) are located in the pelvis, one on each side of the uterus. HORMONES • MAJOR: • ESTROGEN • PROMOTES THE DEVELOPMENT AND MAINTENANCE OF FEMALE SEXUAL CHARACTERISTICS • PROGESTERONE • PREPARE AND MAINTAIN THE BODY FOR PREGNANCY Minor: LH (luteinizing hormone) Hormones Continued triggers ovulation and development of the corpus luteum. FSH(follicle stimulating hormone) released by the anterior pituitary gland HCG (human chorionic gonadotrophin) produced during pregnancy GnRH (gonadotropin-releasing hormone) released during a menstrual cycle or giving birth Relaxin produced during pregnancy Steroid hormones: Estrogen and Progesterone Sex hormones: estrogen Hormones Affect on the Body The two hormones affect the body by controlling the development of female body characteristics such as: Breasts Body Shape Body Hair They also regulate the menstrual cycle and pregnancy. Increases growth of bones during adolescence that lead to adult height and proportions. Homeostasis Progesterone is most active in females during ovulation and pregnancy where it maintains appropriate conditions in the human body to support a developing fetus. Homeostasis Continued • Estrogens- A loss contributes to • Negative effects on the brain and homeostasis • Estrogen helps improve blood flow to the brain and prevents Alzheimer disease • Blocks the production of chemicals contributing to it. • Increases the level of serotonin • a chemical in the brain known to improve mood. • A loss of estrogen can not only affect womens physical health but mental health as well POSITIVE FEEDBACK: Causes Menstrual Cycles • OCCURS BEFORE OVULATION • ESTROGEN CAUSES THE RELEASE OF GNRH(GONADOTROPINRELEASING HORMONE) FROM THE HYPOTHALAMUS • LH(LUTEINIZING HORMONE) FROM THE ANTERIOR PITUITARY • LH CAUSES THE RELEASE OF ESTROGEN Negative Feedback: Stops Menstrual Cycles • Occurs after Ovulation • Corpus luteum secretes progesterone because of the LH hormone • Progesterone inhibits GnRH from the hypothalamus and LH from the anterior pituitary Animation • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/anima tion__positive_and_negative_feedback__quiz_2_.html OVARY FAILURE Hypogonadism • Causes: genetic disorders, infection, liver and kidney disease, radiation • Effects: no hormones are produced, no menstrual cycles • Treatments: Hormone based medicines usually come in pills or skin patches. Ovary Failure Continued DISEASES Diseases Continued Sources • http://www.medterms.com/script/main/art.asp?articlekey=8978 • http://faculty.stcc.edu/AandP/AP/AP2pages/reprod/female1.htm • http://www.healthywomen.org/condition/progesterone • http://www.menopauseatoz.com/00058.shtml • http://www.ovarydisease.com/> • http://www.medicinenet.com/ovarian_cancer/article.htm> • http://www.medicinenet.com/polycystic_ovary/article.htm> • http://www.nlm.nih.gov/medlineplus/ency/article/001195.htm