Skeletal System Osteology – the study/science of bones Human Skeleton • comprised of approximately 206 bones • at birth approximate 270 • change due to fusion of separate bones during early growth • divided into axial and appendicular Axial • skull 22 bones • ear ossicles 6 • vertebrae 26 • hyoid 1 • rib cage 25 Appendicular • pectoral girdle 4 bones • upper extremities 60 • pelvic girdle 2 • lower extremities 60 **overhead and hand-out skeletal system Functions of the Skeleton • five functions of the human skeleton 1. Support •forms rigid framework to which the softer tissues and organs of the body are attached 2. Protection •skull and vertebral column enclose central nervous system (CNS) •rib cage protects heart, lungs, liver spleen •pelvic girdle protects pelvic viscera •even RBC production factory protected within each individual bone 1. Body Movement •serve as anchoring attachments for most skeletal muscles •act as levers 2. Hemopoiesis •red bone marrow produces WBC, RBC, and platelets •approximately 1,000,000 red blood cells/second produced here 3. Mineral Storage •primarily calcium and phosphorus •95% of these minerals found in bones and teeth Calcium •important in muscle contraction •blood clotting •ion movement across the cell Phosphorus •activities of nucleic acids (DNA/RNA) •ATP utilization AXIAL SKELETON SKULL • 8 bones • joined rigidly • protect brain and sense organs FACIAL BONES • framework for facial regoin and support of teeth HYOID BONE • supports tongue, and assists in swallowing EAR OSSICLES (malleus, incus and stapes) • transfer and amplify sound impulses to middle ear VERTEBRAE (vertebral column) • 26 vertebrae • enclose and protect spinal cord • support and permit movement of skull • provide attachment for trunk muscles RIB CAGE • directly involved in mechanics of breathing • protect vital organs APPENDICULAR SKELETON PECTORAL GIRDLE Clavicle and Scapula • serves as attachment for numerous muscles involved in movement of arms BRACHIUM Humerous • anatomically defined as the upper arm • humerous is the only bone FOREARM Ulna and raduis • ulna is the larger of the two bones in lower arm • radius is the small bone, it is located on the thumb side and is responsible for articulation of arm and wrist WRIST AND HAND • 27 bones Carpus • heel of hand Metacarpus • flat of hand Phalanges • fingers PELVIC GIRDLE Os coxae and symphysis pubis • support weight of upper body • protects and supports urinary bladder, reproductive organs, and developing fetus • shape of girdle differs in sexes THIGH Femur • femur is the only lone bone in the thigh • longest, heaviest and strongest bone in the body • major center for blood cell production and mineral storage Patella • protects the knee joint • also referred to as the “knee cap” LOWER LEG Tibia • larger of the two bones in the lower leg • found on medial side of the leg • bears weight of the entire body Fibula • small of the two lower leg bones • important for muscle attachment as opposed to support Ankle • 26 bones Tarsus • heel of the foot Metarsus • arch of the foot Phalanges • toes and distal flat portion of the foot JOINTS • The extent and type of movement determine the name applied to a joint. Bone structure limits the kind and amount of movement in each joint. Some joints are very limited whereas others have a variety of movement ranges. articulate • the interaction between two or more bones, i.e. Bones moving together flexibility • elasticity of the muscle tissue and tissue surrounding joints Types of Joints 1. diarthrotic joints (majority of joints in the body) 2. suture joints (found in skull and pelvic area) 3. disc joints (found in vertebral column) DIARTHROTIC JOINT GROUPS Gliding Joint • two plane or flat bony surfaces that butt against each other, permitting limited gliding movement • e.g. Carpal bones of the wrist Biaxial Ball and Socket Joints • the bones permit movement in two planes, without rotation • e.g. Wrist between the radius and the proximal row of the carpal bones Multiaxial Ball and Socket Joints • permits movement in all planes • e.g. Shoulder and hip joints Hinge Joints • permits a wide range of movement in only one place • e.g. Elbow, ankle, knee joints Saddle Joint • reciprocal reception is found only in the thumb at the carpometacarpal joint and permits ball and socket movements with the exception of rotation Pivot Joint • rotational movement around the long axis 18 • e.g. Rotation (pronation/suppination) of the radius at the radiolnar joint See page for handout Joint Disorders Injuries • dislocation • hyperextension • capsule tears • ligament tear • bone fracture • meniscus or cartilage damage Osteomylithis • infection due to bacteria or virus following an injury Osteoarthritis • due to aging/irritation, abrasion • no known cure Rheumatoid Arthritis • sever pain • affects women 3:1 over men • synovial membrane becomes swollen and inflamed • deformity → cartillage turns to calcium deposit Demineralization • due to lack of Vitamin D, aging and hormonal changes • astronauts often obtain this disorder Gout • usually in the feet, especially big toe Muscular System Myology • the science/study of muscles Muscles • contract when stimulated by electrical impulses • only have power when contracting → cannot push Functions of the Muscular System • three functions of the muscular system 1. • • • • Motion skeletal movement breathing movement of body fluids cardiac movement moves blood 2. Heat Production • muscles constitute approximately 40% of the body’s weight • the continuous fiber activity is important in producing heat in the body 3. • • • Posture and Support maintain posture/offer support around joints certain skeletal muscles even work without really knowing it e.g. neck/head all muscles are: • irritable → respond to stimulus • contractible → works by shortening • extensible → can be returned by opposing force • elastic → can be stretched and returned to original length Over 600 skeletal muscles in the body (most are paired) • the names suggest where the muscle is located TYPES OF MUSCLES I. Smooth Muscle • involuntary, include blood vessels, intestines and lungs II. Striated/Skeletal Muscle • responsible for the voluntary movement of the body III. Cardiac Muscle • only one in body, the heart Muscle System Actions Origin – where the muscle meets the bone that doesn’t move Insertion – where the muscle meets the bone that moves Flexors – muscle that bends joints pulls limbs towards body Extensors – straighten joints Agonist – prime mover → initiates the action Antagonist – relaxes or yields to agonist muscle Synergists – fixators → hold limb/joint steady during the action Hand-out diagrams of Muscle Types FACIAL Frontalis → over frontal bone (eyebrow movement) Orbicularis occuli → surrounds the eyes (blinking) Masseter → opens mouth Temporalis → closes mouth Zygomaticus → elevates the corner of the mouth (smiling) Sternocleidomastoid → turns head ABDOMINAL External oblique, rectus abdominus, internal oblique, transverse abdominus • aid in breathing, defecation, and stabilize spine while lifting PECTORAL GIRDLE Front Pectoralis major → adduct, flexes and rotates the brachium medially Serratus anterior → pulls scapula forward and down Back Trapezius → adducts, elevates scapula → hyperextends the head Latissimus dorsi →adducts arm, drawing it downward and back ward Brachia and Forearm Deltoid →abduct, extend and flex brachium Bicep brachi → two heads, flexes forearm Brachialis → works with bicep to flex forearm Brachioradialis → flexes forearm Tricep brachi → three heads, extends forearm Legs Gracilis, adductor longus, adductor magnus → adduct thigh and flex leg Sartorius → longest muscle in the body →crosses legs Quadricep femoris → four muscles in this group → rectus femoris, vastus lateralis, vastus medialis, vastusintermedius → extend legs Hamstrings → three muscles in this group → bicep femoris, semitendinosus, semimembranosus → flexion of leg at the knee Tibialis anterior → dorsi flexes the foot Peroneous Longus → plantar flexes the foot and eversion of foot Gastrocnemius → flexes knee, plantar flexes foot Soleus → plantar flexion of the foot • Textbook • p.40 Sliding Theory of Muscle Contraction • p.41 Diagrams – reproduce and understand • p.43 Reproduce Sliding Filament Theory of Contraction • stimulated muscle contracts as a result of the shortening of its individual fibres • shortening of these fibres is accomplished in turn by the shortening of their own myofbrils which is actually the shortening of distance between “z” lines • the thick myosin and thin actin filaments remain the same length during contraction → instead, the think “slide” over the thick MUSCLE TISSUE STRUCTURE Epimysium – a fibrous outer sheath of connective tissue surrounding a skeletal muscle Perimysium – fascia (connective tissue) surrounding a bundle of muscle fibres Endomysium – the connective tissue sheath the surrounds each skeletal muscle fibre, separating the muscle cell from one another Fasciculi – a small bundle of muscles or nerve fibres MUSCLE CELL STRUCTURE Sarcolemma – the cell membrane of a muscle fibre Sarcoplasm – the cytoplasm within a muscle fibre Myofibrils – a bundle of contractile fibres within a muscle cell (thick and thin) SARCOMERE STRUCTURE Sarcomere – the portion of a striated muscle fibre between the two adjacent “Z” lines that is considered the functional unit of a myofibril Myosin – “A” band – contain thick myofibrils – dark in appearance Actin – “I” band – contain thin myofibrils – light in appearance Z line – thin, dark center of each i-band. Basic sub-unit of striated muscle contraction Cross-bridge – sliding of the myofibrils produced by the action of cross-bridges that extend from the myosin toward the actin • pull actin from each side toward the middle of the cell • extend from the axis of the thick myofilaments to form “arms” that terminate in globular heads Isotonic Contraction – the force of contraction remains relatively constant throughout the shortening process CIRCULATORY SYSTEM Three functions of the circulatory system 1. • • • Transport respiratory – O2 and CO2 nutritional – absorbs products through liver excretory – waste processed through kidneys 2. Regulation • hormones carried to target tissues 3. Protection • clotting mechanisms • leukocytes (WBC) attack disease HEART • four-chambered, muscular organ • located in chest with 2/3 of the heart left of the midline with the point downward • upper right and left atria contract simultaneously and empty into ventricles • lower right and left ventricles also contract in synch to empty heart Right Atrium • collects venous blood from superior vena cava (upper body) and inferior vena cava (lower body) Left Atrium • received oxygenated blood from lungs through pulmonary veins (two from each lung) Right Ventricle • right atrial blood enters via tricuspid and is pumped to lungs through pulmonary arteries Left Ventricle • blood from left atrium enters via bicuspid valve • O2 blood leaves here via ascending aorta Cardiac Cycle contraction phase – systole, the “lub” relaxation phase – diastole, the “dub” 3/8 of time is spend in the “dub” phase above applies to ventricles, opposite is true for atrial systole and diastole Blood Vessels • blood leaving heart passes through vessels • these vessels diminish in size as they go • arteries-arterioles-capillaries Arteries • very elastic – stretch with the hearts contraction • carry oxygen rich blood Capillaries • “functional units” of the circulatory system • gas and nutrient exchange takes place here Veins • low pressure is insufficient to return blood to heart without venous valves Venules • performs similar function as capillaries Cardiac Output • measured in mL/min.=stroke vol/mL/beat X cardiac rat (beats/min) • average stroke volume=70-80mL/beat • average cardiac rate= 70 beats/min RESPIRATORY SYSTEM • Three functions of the respiratory system are all similar 1. Ventilation • breathing 2. Gas exchange • oxygen and carbon dioxide transfer in lungs 3. O2 utilization Major Passages Nasal Cavity – Nose • warms, moistens and cleans air • highly vascular, large surface area • also contains olfactory cells • provides sound resonance when speaking Pharynx • connects nasal cavity with larynx at the base of skull • has both respiratory and digestive functions Larynx • connects to trachea • prevents food and liquid from entering lungs • permits air passage Trachea (windpipe) • connects larynx to primary bronchi Bronchial Tree • gas exchange passages branch apart like branches of a tree Lungs • hold air for gas exchange • house the bronchi etc. Alveoli • functional units of respiration • gas exchange takes place here • enormous surface area