Tackling overdispersion in NHS performance indicators Robert Irons (Analyst – Statistician) Dr David Cromwell (Team Leader) 20/10/2004 Outline of presentation • • • • • NHS Star Ratings Model Criticism of some of the indicators The reason – overdispersion Options for tackling the problem Our solution – an additive random effects model • Effects on the ratings indicators 2 Performance Assessment in the UK •1990s: Government focused on efficiency •1997: Labour replaces Conservative government •Late 90s: Labour focus on quality & efficiency – Define Performance Assessment Framework – Publish NHS Plan in 2000 – Commission for Health Improvement (CHI) created – Performance ratings first published in 2001, responsibility passed to CHI for 2003 publication – Healthcare Commission replaces CHI on April 2004, has broader inspection role 3 NHS Performance Ratings • An ‘at a glance’ assessment of NHS trusts’ performance – – • Focus on how trusts deliver government priorities – • Performance rated as 0, 1, 2, or 3 stars Yearly publication Linked to implementation of key policies • Priorities and Planning framework • National Service Frameworks Have limited role in direct quality improvement – Modernisation agency helps trusts with low rating 4 Scope of NHS ratings 2001 2002 2003 2004 Mental health trusts Primary care trusts Acute trusts Ambulance trusts 5 The ratings model • • Overall rating derived from many different indicators – and affected by Clinical Governance Reviews Two types of indicators, organised in 4 groups – Key targets & Balanced Scorecard indicators – BS indicators grouped into 3 focus areas • Patient focus, clinical focus, capacity & capability Trust Type Acute Ambulance Mental Health Primary Care Trusts Key Targets 9 4 7 9 Balanced Scorecard 35 19 31 33 6 Combining the indicators • • Indicators are measured on different scales – Categorical (eg. Yes/No) – Proportional (eg. proportion of patients waiting longer than 15 months) – Rates (eg. mortality rate within 30 days following selected surgical procedures) Further complication – Performance on some indicators is measured against published targets – define thresholds – Performance on other indicators is based on relative differences between trusts 7 Combining the indicators • • • Indicators first transformed so they are all on an equivalent scale Key targets assigned to three levels: – – achieved under-achieved – significantly under-achieved Balanced scorecard indicators – – – – – 1 – significantly below average (worst performance) 2 – below average 3 – average 4 – above average 5 – significantly above average (best performance) 8 Transforming the indicators • • Key target indicators transformed using thresholds defined by government policy Balanced scorecard indicators transformed via several methods – Percentile method – Statistical method – Absolute method, if policy target exists – Mapping method (for indicators with ordinal scales) Trust type Acute trusts Ambulance trusts Mental health trusts Primary care trusts Percentile 11 3 9 11 Statistical 12 8 9 11 Absolute 8 3 5 4 Defined mapping 4 5 8 7 9 Transforming the indicators - the statistical method Trust type Indicators Acute trusts Ambulance trusts Mental health trusts Primary care trusts Clinical indicators 4 Patient survey 5 5 4 5 Staff survey 3 3 3 3 Change in rate indicators 2 3 10 The old statistical method • • • Based on simple confidence intervals 95% and 99% confidence intervals calculated for a trust’s indicator value Trust confidence interval compared with the overall national rate (effectively a single point) Significantly below average 1 no 99% confidence interval overlap: higher values Below average 2 no 95% confidence interval overlap: higher values Average 3 overlapping 95% confidence intervals, eg England: 5.51% to 5.55% Above average 4 no 95% confidence interval overlap: lower values Significantly above average 5 no 99% confidence interval overlap: lower values 11 The old statistical method - problematic • • • Not a proper statistical hypothesis test Differentiating between trusts based on differences that exceed levels of sampling variation On some indicators, this led to the assignment of too many NHS trust to the significantly good/ bad bands on some indicators 12 Working example - standardised readmission rate of patients within 28 days of initial discharge Trusts with > 50 readmissions 2 SAR 1.5 1 0.5 0 Significantly below average Below average Average Above average Significantly above average Total 32 6 40 13 49 140 13 Readmissions within 28 days of discharge - funnel plot (2003/04 data) Old band 99% limits 95% limits 2.14934 3 1 1 33 3 3 3 3 3 3 55 3 3 5 4 5 1 1 1 1 1 1 1 1 11 1 1 1 1 1 11 11 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 3 3 1 333 3 3 33 3 3 332 3 3 3 3 331 33 333 3 33 3 3 3 3 3 3 33 4 3 3 33 53 3 43 353335 5 3 3 4355 45 443 43 4 5 5 34 5 55 5 55 5 5 5 5 55 555 55 5 5 55 5 5 55 5 5 5 1 11 1 11 3 1 1 1 1 5 5 -.149339 2.5993 5607.48 Expected re-admissions 14 Mortality within 30 days of selected surgical procedures - funnel plot (2003/04 data) Old band 99% limits 95% limits 1.97137 2 3 2 1 2 3 3 3 3 3 1 1 1 2 3 3 1 3 2 2 3 33 33 3 1 3 2 3 3 3 3 23 3 3 33 3 3 3 3 3 3 3 3333 3 3 3 3 3 3 3 3 3 3 333 3 3 33 33 3 3 333 3 33 3 3 33 3 3 33 3 33 3 33 3 3 3 3 3 3 33 3 3333 3 3 33 3 3 3 3 3 3 3 3 3 3 3 3 3 3 4 33 3 33 33 333 3 4 4 5 3 4 44 444 3 5 4 5 5 5 3 3 3 3 3 5 4 5 5 3 3 5 5 5 5 0 55 .641582 348 exp 15 Z scores • • Standardised residual Z scores are used to summarise ‘extremeness’ of the indicators • Funnel plot limits approximate to the naïve Z score • Naïve Z score given by – Zi = (yi –t)/si – Where yi is the indicator value, and si is the local standard error 16 Dealing with over-dispersion • Three options were considered – Use of an ‘interval null hypothesis’ – Allow for over-dispersion using a ‘multiplicative variance model’ – …or a ‘random-effects additive variance model’ 17 Interval null hypothesis • • • • • • • • Similar to the naïve Z score or standard funnel limits Uses a judgement of what constitutes a normal range for the indicator Define normal range (eg percentiles, national rate ± x%) Funnel limits then defined as: – Upper/ lower limit = Range limit ± (x * si0) Reduces number of significant results But might be considered somewhat arbitrary Interval could be defined based on previous years’ data, or prior knowledge Makes minimal use of the sampling error 18 Interval null hypothesis -a funnel plot Old band 99% limits 95% limits 2.15319 3 1 1 33 3 3 3 3 3 3 55 3 3 5 4 5 1 1 1 1 1 1 1 1 11 1 1 1 1 11 11 11 1 1 1 1 1 1 1 2 312 3 1 13 2 1 11 1 33 1 1 333 33333 3 3 3 3 3 3 3 3 3 3 3 3 33 3 333 3 3 3 33 33 3333 3 33 4 53 3 44 443 43 4 5 5 5 5 3 3 455 5 5 34 5 55 5 55 5 5 5 5 55 555 55 5 5 5 5 5 55 5 5 5 5 1 11 1 11 3 1 1 1 1 5 5 -.136105 2.5993 5607.48 exp 19 Multiplicative variance model • • • • • • Inflates the variance associated with each observation by an over-dispersion factor ( ): – Zi2 = Pearson X2 – = X2 / I Limits on funnel plot are then expanded by Do not want to be influenced by the outliers we are trying to identify Data are first winsorised (shrinks the extreme zvalues in) Over dispersion factor could be provisionally defined based on previous years’ data Statistically respectable, based on a ‘quasilikelihood’ approach 20 Multiplicative over-dispersion -a funnel plot (not winsorised, = 21.45) Old band 99% limits 95% limits 2.19029 3 1 1 33 3 3 3 3 3 3 55 3 3 5 4 5 1 1 1 1 1 1 1 1 11 1 1 1 1 11 11 11 1 1 1 1 1 1 1 1 1 2 312 3 1 13 2 1 33333 3 3 333 3 33 3 313 13 3 331 33 3 3 3 3 3 3 33 3 3 33 33 333 3 33 4 3 53 3 43 43 4 5 5555 5 5 3 3 455 5 45 5544 5 55 5 554 5 5 5 5 5 5 5 5 55 5 5 55 5 5 5 1 11 1 11 3 1 1 1 1 5 5 -.190294 2.5993 5607.48 Expected re-admissions 21 Multiplicative over-dispersion -a funnel plot (10% winsorised, = 13.97) Old band 99% limits 95% limits 2.19144 3 1 1 33 3 3 3 3 3 3 55 3 3 5 4 5 1 1 1 1 1 1 1 1 11 1 1 1 1 11 11 11 1 1 1 1 1 1 1 1 1 2 312 3 1 13 2 1 33333 3 3 333 3 33 3 313 13 3 331 33 3 3 3 3 3 3 33 3 3 33 33 333 3 33 4 3 53 3 43 43 4 5 5555 5 5 3 3 455 5 45 5544 5 55 5 554 5 5 5 5 5 5 5 5 5 5 5 55 5 5 5 5 1 11 1 11 3 1 1 1 1 5 5 -.191437 2.5993 5607.48 Expected re-admissions 22 Winsorising • • Winsorising consists of shrinking in the extreme Zscores to some selected percentile, using the following method. 1. Rank cases according to their naive Z-scores. 2. Identify Zq and Z1-q, the (100*q)% most extreme top and bottom naive Z-scores, where q might, for example, be 0.1 3. Set the lowest (100*q)% of Z-scores to Zq, and the highest (100*q)% of Z-scores to Z1-q. These are the Winsorised statistics. This retains the same number of Z-scores but discounts the influence of outliers. 23 Winsorising .248555 • Non winsorised Fraction Winsorising 0 -14.909 11.148 zi .248555 Fraction 10% winsorised 0 -14.909 11.148 zi 24 Random effects additive variance model • • • • • • • Based on a technique developed for meta-analysis Originally designed for combining the results of disparate studies into the same effect In meta-analysis terms, consider the indicator value of each trust to be a separate study Essentially seeks to compare each trust to a ‘null distribution’ instead of a point 2 Assumes that E[yi] = i, and V[i] = ˆ Uses a method-of-moments method to estimate ˆ 2 (Dersimonian and Laird, 1986) Based on winsorised estimate of 25 Random effects additive variance model • • If ( I ) < ( I – 1) then – the data are not over-dispersed, and ˆ 2 = 0 – use standard funnel limits/ naïve Z scores Otherwise: Iˆ ( I 1) 2 ˆ 2 w w w i i • • k i i i Where wi = 1 / si2 The new random-effects Z score is then calculated as: z D i y s ˆ i 2 0 2 i 26 Comparing to a ‘null distribution’ Trusts with > 50 readmissions 2 SAR 1.5 1 0.5 0 27 Additive over-dispersion -a funnel plot (20% winsorised) Old band 99.8% limits 95% limits 1.99535 .004654 2.5993 5607.48 Expected re-admissions 28 Effects on the banding of trusts - Readmissions 2002/03 data Significantl y below average Below average Average Above average Significantly above average Previous banding method 32 6 40 13 49 Random-effects (20% winzorised) 3 9 101 21 6 29 Why we chose the additive variance method • • • • Generally avoids situations where two trusts which have the same value for the indicator get put in different bands because of precision A multiplicative model would increase the variance at some trusts more than at others – e.g. a small trust with large variance would be affected much more than a large trust with small variance By contrast, an additive model increases the variance at all trusts by the same amount Better conceptual fit with our understanding of the problem, that the factors inflating variance affect all trusts equally, so an additive model is preferable 30 References: DJ Spiegelhalter (2004) Funnel plots for comparing institutional performance. Statistics in Medicine, 24, (to appear) DJ Spiegelhalter (2004) Handling over-dispersion of performance indicators (submitted) R DerSimonian & N Laird (1986) Meta-analysis in clinical trials. Controlled Clinical Trials, 7:177-188 Acknowledgements: David Spiegelhalter Adrian Cook Theo Georghiou Thank you 31