CROHN’S DISEASE WHAT IS IT? A form of chronic inflammatory bowel disease, in which parts of the digestive tract become inflamed. This disease may affect either the small or large intestine. INCIDEN CE: Crohn’s disease occurs most commonly in men than women. Usually, the age of onset is between 10-35 years of age. About 7 of every 100,000 people in the USA have Crohn’s disease. RISK FACTORS: There are many risk factors that may contribute to Crohn’s disease, but the cause is unknown. Certain risk factors that can be identified include age, ethnicity, family history, cigarette smoking, area of residency (increased risk in urbanized areas), & one’s immune response to intestinal bacteria. PATHOPHYSIOLOGY: Crohn’s disease is an inflammatory disorder. This disease affects the digestive tract (small/large intestine, or colon) location varies greatly for each person. Inflammation is thought to begin in the sub mucosa and spreads to the mucosa and serosa. Tissue injury is due to the activated neutrophils and macrophages (white blood cells) in the body, which promote inflammation. This process of inflammation is thought to be caused from increased levels of interferon-gamma and tumor necrosis factor-alpha in one’s body . REFERENCES Crohn's disease - National Library of Medicine - PubMed Health. (2012, October 29). National Center for Biotechnology Information. Retrieved April 16, 2013, from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH 0001295/ Davidson, T., Newton, D., & Frey, R. (2011). Crohn's disease. In L. J. Fundukian (Ed.), Gale Encyclopedia of Medicine, Vol. 2. (4th ed.). Detroit: Gale. Retrieved April 19, 2013, from NRCX via Gale: http://-find.galegroup.com.libcat.ferris.edu /nrcx/start.do?prodId=NRC CROHN’S DISEASE STEPHANIE TWAIT NURS 300 Elsevier NCLEX Exam Practice Question of the Week: NCLEX Exam Practice Question of the Week - 03/16/11. (n.d.). Elsevier NCLEX Exam Practice Question of the Week. Retrieved April 16, 2013, from http://elseviernclexreview.blogspot.com/2011/03/ nclex-exam-practice-question-of-week_16.html Gastrointestinal Diseases NCLEX Review Questions Part 1 RNpedia.com . (n.d.). RNpedia.com . Retrieved April 16, 2013, from http://www.rnpedia.com/home/exams/nclexexam/gastrointestinal-diseases-nclex-reviewquestions-part-1 Huether, Sue E., and Kathryn L. McCance. "Alterations of Digestive Function." Understanding Pathophysiology. St. Louis, Mo: Elsevier, 2012. 909-10. Print. Ladwig, G., & Ackley, B. (2011). Mosbey’s guide to nursing diagnosis. (3 ed.). Maryland Heights, MS: Mosby Elsevier. Wexler, Barbara. "Crohn's disease." Gale Encyclopedia of Nursing and Allied Health. Ed. Jacqueline L. Longe. Vol. 1. 2nd ed. Detroit: Thomson Gale, 2006. Nursing Resource Center. Gale. Ferris State University Library. 19 Apr. 2013 http://0-find.galegroup.com.libcat.ferris.edu/ nrcx/infomark.do?&source=gale&prodId=NRC& userGroupName=lom_ferrissu&tabID=T001& docId=DB2621410216&type=retrieve&content Set=GREF&version=1.0 Image from The University of Florida Academic Health Center Website: https://ufandshands.org/crohns-disease CLINI CAL MANIFESTATI ONS: Diarrhea(persistent/watery) Bloody stool Abdominal Pain/cramping Fatigue Anorexia Loss of appetite Fever Joint pain Arthritis Mouth sores/ulcers Eye inflammation POTENTIAL COMPLICATI ONS: Fistulas (internal or external) Ulcers Bowel Obstruction Malnutrition Anal fissure Colon cancer LIFE SPAN: Crohn’s can interfere with growth and development in children. May affect school, social, and family life for children. CULTURAL CONSIDERATIONS More prevalent in whites, than African Americans or Asian Americans. 2 to 4 times more likely among Jewish people than any other ethnic group. POTENTIAL OUT COMES Outcomes expected for patients in relation to the previous diagnosis include maintaining a steady weight, identifying foods that negatively affect their GI system, identify nutritional requirements, identify own pain & establish a comfortable level, report pain regimens that alleviate pain to a comfortable level, identify uncontrollable factors related to their health, participate in planning, and verbalize hope for the future. No cure for Crohn’s disease. Treatment is supportive, not curative. Treatment varies greatly for each patient and depends on what part of digestive tract is affected. Goals of treatment are to manage symptoms, put the disease in remission, and avoid relapse. Recommended to eat a low-residual diet (low in fiber & hard to digest foods) Children with Crohn’s may need a high-caloric/nutrient diet due to vitamin and mineral deficiencies. Avoid foods that cause flare ups (specific to each person) Patient’s usually take medications to alleviate pain and discomfort. Surgery to remove diseased part of the digestive tract. HEALTH CARE PROFESSI ONALS ON YOUR TEAM Patient’s may want, need, or have many different health care professionals in dealing with Crohn’s disease. These professionals include: Imbalanced nutrition: less than body requirements r/t diarrhea and altered ability to digest and absorb food. Acute pain r/t increased peristalsis Powerlessness r/t chronic disease. 1. 2. TREATMENT NURSING D IAGNOSIS NCLEX QUESTIONS Primary health care provider or gastroenterologist: For diagnosis and check ups. Surgeon: If surgery is needed Nurse: For teaching & managing disease Dietician: Client teaching on managing diet Social Worker: Educating patient and providing support. 3. 4. Older patients with longstanding or severe Crohn’s disease can exhibit which of the following? a. Nausea and Vomiting b. Hypoalbuminemia c. Hyperalbuminemia d. Decreased sedimentation rate Crohn’s disease is a chronic relapsing disease. Which area of the GI tract is involved in this disease? a. Entire length of L intestine b. The sigmoid area only c. The S intestine & colon, the entire thickness of the bowel. d. The S intestine, mucosa only A 28-year-old client is admitted with inflammatory bowel syndrome (Crohn’s disease). Which therapies should the nurse expect to be part of the care plan? Select all that apply. a. Lactulose therapy b. High-fiber diet c. High-protein milkshakes d. Corticosteroid therapy e. Antidiarrheal medications The nurse is reviewing the record of a female client with Crohn’s disease. Which stool characteristics should the nurse expect to note documented in the client’s record? a. Diarrhea b. Chronic constipation c. Constipation alternating with diarrhea d. Stools constantly oozing from the rectum