Tetany By: Hannah Gilman What is it? • Muscle cramps, spasms or tremors • Can occur anywhere ▫ Face, fingers, calves • Due to low calcium levels: hypocalcemia ▫ Ca concentration in extracellular fluids drops ▫ Affects the nervous system ▫ Sending impulses to skeletal muscles Hyperventilation • Removes too much CO2: resulting in respiratory alkalosis (lower H+ and increased pH) • Increases Calcium proteinate and lowers free Ca++ • Increased excitability causes spontaneous tingling in fingers and toes due to increased sensitivity in the motor axons and peripheral nerves Parathyroid hormone regulates Ca++ Tetany is a major sign of hypoparathyroidism Causes • • • • • • • • Diarrhea Kidney disease Thyroid or pancreas problems Pregnancy and breast feeding Malnutrition Vitamin D deficiency Some medications Calcium deficiency Symptoms of Tetany Non-Severe Severe • • • • • • • • • • • Abdominal pain Chronic diarrhea Muscle pain Tingling in hands or feet Twitching fingers Loss of muscle coordination Loss/change in vision Paralysis Seizures Slurred speech Sudden difficulty with memory, thinking, talking, writing or reading • Sudden weakness or numbness on one side Who Does it Affect? • Anyone ▫ As a consequence of sustained hyperventilation or following excessive vomiting ▫ Often from an endocrine disorder • • • • • Neonatal, children, cows, chickens and dogs Occurs more in temperate zones/winter Marathoners Anorexic or bulimic Old people Treatment • Detection of low calcium levels is important ▫ Tetany can be fatal if it involves laryngeal or pharyngeal muscles; which blocks the airway • IV Treatment ▫ Calcium carbonate is used in the initial stage of Hypocalcemia ▫ Calcium gluconate is used for muscle cramps or nerve weakness ▫ Calcium chloride is for patients in serious condition Calcium Factors enhancing absorption Factors that limit absorption • • • • • Large amounts of phytic acid • Excess of phosphorus and magnesium in diet • Polyphenols in tea • Vitamin D deficiency • Diarrhea • Old age Parathyroid hormone Glucose and lactose Digestive motility Vitamin D & K Age 0-6 mo 7-12mo 1-3 yr Daily 210 mg Calcium Intake 270 mg * Upper limit 2500 mg 500 mg 4-8 yr 9-18 yr 19-50 yr Over 50 yr 800 mg 1300 mg 1000 mg 1200 mg How vitamin D & Calcium work together • Vitamin D facilitates Ca absorption in the intestine ▫ By going thru the intestine and into the blood stream • Helps reclaim Ca in kidneys • 1% of the body’s Ca is in the blood plasma, the rest is in the bones • RDA Calcium: ~1000mg • RDA vitamin D: ~600IU Where they can be found Calcium Vitamin D • • • • • • • • • The Sun: 400 IU/15min • Salmon: 238 IU • Sardines: 136 IU • Canned tuna: 136 IU • 1% milk: 99 IU • Mushrooms: 73 IU • Special K cereal: 30 IU • Others: cheeses, cereal, energy bars, eggs, butter, liver Yogurt: 450 mg Parmesan cheese: 390 mg 1% milk: 300 mg Spinach: 250 mg Salmon: 210 mg Chocolate pudding: 160 mg Tofu: 140 mg Others: cheese, kale, soy milk, energy bars Diet Plan: Day 1 Breakfast Food Ca VitD VitK Kcal (mg) (IU) (mg) Yogurt 419 0 537 208 Fortified milk 285 105 366 122 Food Ca VitD VitK Kcal (mg) (IU) (mg) Grape nut flakes 11 401 99 106 Shrimp cocktail 91 147 23 218 Banana 6 0 422 105 Spinach 500 0 334 14 TOTALS 721 506 1424 541 Swiss cheese 214 12 21 103 Mushrooms 1 27 110 8 Italian dressing 8 0 28 14 TOTALS 814 186 516 357 Snack Food Ca VitD (mg) (IU) Chocolate 188 milkshake 58 VitK Kcal (mg) 250 211 Lunch Diet Plan: Day 1 Dinner Food Ca VitD VitK Kcal (mg) (IU) (mg) Brown Rice 0 0 0 160 Salmon 420 476 704 254 Kale 90 0 299 34 Yam 26 0 1224 176 Sour cream 40 0 0 60 Fortified milk 570 210 732 244 TOTALS 1146 686 2959 928 Totals for the Day Ca VitD VitK Kcal (mg) (IU) (mg) 2869 1436 5149 2037 Diet Plan: Day 2 Breakfast Food Ca VitD VitK Kcal (mg) (IU) (mg) Cocoa Pebbles 40 40 42 115 Chocolate soy milk 300 120 350 140 Kiwi 60 0 552 108 Honey 100 peanut bar 80 115 TOTALS 240 Snack 500 1059 Lunch Food Ca VitD VitK (mg) (IU) (mg) Kcal 439 11 264 431 200 Grilled cheese on whole wheat 120 0 934 287 563 Chili w/beans TOTALS 559 11 1198 718 Food Ca VitD VitK Kcal (mg) (IU) (mg) Vanilla milkshake 203 61 290 185 Diet Plan: Day 2 Dinner Food Ca VitD (mg) (IU) VitK Kcal (mg) Tuna 28 272 620 312 Spinach 500 0 334 14 Muenster cheese 203 0 38 104 Bell Peppers 8 0 158 20 Mushrooms 1 27 110 8 Fortified milk 285 105 366 122 TOTALS 1025 404 1626 580 Totals Ca VitD for the (mg) (IU) Day 2287 716 VitK (mg) Kcal 4173 2046 Diet Plan: Day 3 Lunch Food Ca VitD VitK (mg) (IU) (mg) Kcal Power Boost smoothie 600 240 810 280 Tuna salad sandwich 76 72 168 326 Mushrooms 3 73 301 21 Ranch 9 1 18 137 TOTALS 688 386 1297 764 VitK (mg) Kcal 260 170 Breakfast Food Ca VitD VitK Kcal (mg) (IU) (mg) Omelet w/ sausage 64 Fortified milk 285 105 366 122 Whole wheat biscuit 155 10 200 199 Orange 52 0 237 62 TOTALS 556 168 965 550 53 162 167 Food Snack Ca VitD (mg) (IU) Banana 200 crème yogurt 80 Diet Plan: Day 3 Dinner Totals Ca for the (mg) Day Food Ca VitD VitK Kcal (mg) (IU) (mg) Salmon 420 476 704 254 Baked potato 0 0 0 70 Swiss cheese 224 13 22 103 Spinach 250 0 167 7 Mushrooms 3 73 301 21 Fortified milk 285 105 366 122 TOTALS 1182 667 1560 577 2626 VitD (IU) VitK (mg) Kcal 1301 4082 2061 Questions 1. What two components must work together to prevent tetany and osteoporosis? 1. Calcium & Vitamin D 2. What is the best source of vitamin D? 2. Sunshine! 3. What percent of Ca is in the blood plasma? Where is the majority held? 3. 1% in the blood plasma & 99% in the bones Bibliography "Tetany." - Symptoms, Causes, Treatments. Healthgrades, 02 May 2011. Web. 03 Mar. 2012. <http://www.bettermedicine.com/article/tetany>. Blakemore, Colin. "Tetany." Encyclopedia.com. The Oxford Companion to the Body, 2001. Web. 03 Mar. 2012. <http://www.encyclopedia.com/topic/tetany.aspx>. Dr.John. "Hypocalcemia - Causes, Symptoms and Treatment." Current Health Articles and Tips. Howshealth, 04 Sept. 2010. Web. 03 Mar. 2012. <http://howshealth.com/hypocalcemia/>. "Calcium Rich Foods, Foods With Calcium." , Calcium Deficiency Symptoms. Fat Free Kitchen, 2005. Web. 03 Mar. 2012. <http://www.fatfreekitchen.com/nutrition/calcium.html>. Food Composition Table. Boston: McGraw-Hill Higher Education, 2009. Print. Wardlaw, Gordon M., and Anne M. Smith. Contemporary Nutrition. New York: McGraw-Hill, 2009. Print. Drezner, Marc, and Kimberly Hoben. "Vitamin D and Calcium Absorption." Sunset Tan. Sunsettan, 17 Sept. 2010. Web. 07 Mar. 2012. <http://www.sunsettan.ca/vitamin-dand-calcium-absorption/>.